World's Best Scientists 2026 revealed!
Xosé R. Bustelo

Xosé R. Bustelo

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
16469
World Ranking
1515
National Ranking
18

Xosé R. Bustelo publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Xosé R. Bustelo sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 167 publications — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Xosé R. Bustelo D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Xosé R. Bustelo sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 68 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Xosé R. Bustelo is affiliated with the University of Salamanca in Spain and has a research portfolio spanning over a hundred publications. Their work mainly intersects the fields of biochemistry, genetics, molecular biology, and medicine, with significant contributions to subfields such as molecular biology, oncology, cell biology, genetics, and immunology.

The scientist's research covers multiple topics including cancer-related molecular pathways, protein kinase regulation and GTPase signaling, chronic lymphocytic leukemia research, ubiquitin and proteasome pathways, RNA research and splicing, Hippo pathway signaling and YAP/TAZ, and RNA modifications in cancer.

Frequent publication venues for Bustelo include:

  • Cancers
  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Oncogene

Among recent papers are the following notable publications:

  • "Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia" (2022, Molecular Cancer)
  • "Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis" (2021, The EMBO Journal)
  • "HERC Ubiquitin Ligases in Cancer" (2020, Cancers)
  • "VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma" (2020, Nature Communications)
  • "A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors" (2022, Cell Reports)

The scientist has collaborated frequently with other researchers, including:

  • L. Francisco Lorenzo-Martín
  • Balbino Alarcón
  • Isabel Fernández-Pisonero
  • Mercedes Dosil
  • Myriam Cuadrado

Xosé R. Bustelo's research contributions include extensive exploration of molecular signaling mechanisms and pathways critical to cancer biology and cellular proliferation. Their work on GTPase signaling and ubiquitin ligases contributes to understanding cellular regulation and oncogenic processes.

Best Publications

  • Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

    Z Songyang;S E Shoelson;J McGlade;P Olivier

  • S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells

    Wolf Dietrich Hardt;Li Mei Chen;Kornel E. Schuebel;Xosé R. Bustelo

  • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

    Piero Crespo;Piero Crespo;Kornel E. Schuebel;Amy A. Ostrom;J. Silvio Gutkind

  • GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

    Xosé R. Bustelo;Vincent Sauzeau;Inmaculada M. Berenjeno

  • Regulatory and Signaling Properties of the Vav Family

    Xosé R. Bustelo

  • Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

    Akhilesh Pandey;Alexandre V. Podtelejnikov;Blagoy Blagoev;Xosé R. Bustelo

  • Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

    Xosé R. Bustelo;Jeffrey A. Ledbetter;Mariano Barbacid

  • Phosphorylation‐dependent and constitutive activation of Rho proteins by wild‐type and oncogenic Vav‐2

    Kornel E. Schuebel;Nieves Movilla;José Luis Rosa;Xosé R. Bustelo

  • Biological and Regulatory Properties of Vav-3, a New Member of the Vav Family of Oncoproteins

    Nieves Movilla;Xosé R. Bustelo

  • Vav proteins, adaptors and cell signaling.

    Xosé R Bustelo

  • Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins

    Daniela Poppe;Imke Tiede;Gerhard Fritz;Christoph Becker

  • Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.

    Crespo P;Bustelo Xr;Aaronson Ds;Coso Oa

  • Tyrosine Phosphorylation Mediates Both Activation and Downmodulation of the Biological Activity of Vav

    Miguel López-Lago;Hyunmi Lee;Cristina Cruz;Nieves Movilla

  • The 90S Preribosome Is a Multimodular Structure That Is Assembled through a Hierarchical Mechanism

    Jorge Pérez-Fernández;Ángel C. Román;Javier De Las Rivas;Xosé R. Bustelo

  • The Vav–Rac1 Pathway in Cytotoxic Lymphocytes Regulates the Generation of Cell-mediated Killing

    Daniel D. Billadeau;Kathryn M. Brumbaugh;Christopher J. Dick;Renee A. Schoon

  • Rac1 function is required for Src-induced transformation: Evidence of a role for Tiam1 and Vav2 in Rac activation by Src

    Joan Marc Servitja;Maria Julia Marinissen;Akrit Sodhi;Xosé R. Bustelo

  • T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.

    Nuria Martínez-Martín;Elena Fernández-Arenas;Saso Cemerski;Pilar Delgado

  • Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.

    Kornel E. Schuebel;Xose R. Bustelo;Xose R. Bustelo;David A. Nielsen;Byoung Joon Song

  • Rac1 mediates STAT3 activation by autocrine IL-6

    Tatjana R. Faruqi;Dolores Gomez;Xosé R. Bustelo;Dafna Bar-Sagi

  • Human Proteinpedia enables sharing of human protein data.

    Suresh Mathivanan;Suresh Mathivanan;Mukhtar Ahmed;Natalie G Ahn;Hainard Alexandre

Frequent Co-Authors

Mariano Barbacid
Mariano Barbacid Spanish National Cancer Research Centre
Piero Crespo
Piero Crespo Spanish National Research Council
Balbino Alarcón
Balbino Alarcón Spanish National Research Council
Eugenio Santos
Eugenio Santos University of Salamanca
Pedro M. Fernandez-Salguero
Pedro M. Fernandez-Salguero University of Extremadura
J. Silvio Gutkind
J. Silvio Gutkind University of California, San Diego
Miguel Vicente-Manzanares
Miguel Vicente-Manzanares University of Salamanca
Oscar Llorca
Oscar Llorca Spanish National Research Council
Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center

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