D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 50 Citations 7,704 92 World Ranking 3709 National Ranking 49

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Cell biology, VAV1, GTPase, Tyrosine phosphorylation and Signal transduction are his primary areas of study. His research related to GTP-binding protein regulators and Syk might be considered part of Cell biology. His VAV1 research is multidisciplinary, incorporating elements of Molecular biology, Proto-Oncogene Proteins c-vav, RHOA and Mitogen-activated protein kinase.

His GTPase research is multidisciplinary, incorporating perspectives in RhoG, GTP', Small GTPase and Rac GTP-Binding Proteins. His work carried out in the field of Tyrosine phosphorylation brings together such families of science as Tyrosine kinase and Receptor tyrosine kinase. Xosé R. Bustelo works mostly in the field of Phosphorylation, limiting it down to concerns involving VAV2 and, occasionally, Cell signaling.

His most cited work include:

  • Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. (853 citations)
  • S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells (713 citations)
  • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product (705 citations)

What are the main themes of his work throughout his whole career to date?

Xosé R. Bustelo spends much of his time researching Cell biology, GTPase, Signal transduction, Cancer research and VAV1. His studies in Cell biology integrate themes in fields like Proto-Oncogene Proteins c-vav and Cytoskeleton. His study in GTPase is interdisciplinary in nature, drawing from both Molecular biology, RhoG, GTP', RHOA and Rac GTP-Binding Proteins.

As a member of one scientific family, Xosé R. Bustelo mostly works in the field of Molecular biology, focusing on Gene expression and, on occasion, Complementary DNA. His Signal transduction research includes themes of Autocrine signalling and Effector. His Cancer research study incorporates themes from Carcinogenesis, Gene, Oncogene and Lymphoma.

He most often published in these fields:

  • Cell biology (59.63%)
  • GTPase (31.06%)
  • Signal transduction (26.71%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (59.63%)
  • Cancer research (19.88%)
  • Carcinogenesis (11.18%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Cancer research, Carcinogenesis, MAPK/ERK pathway and GTPase. His Cell biology research includes elements of VAV1, Ribosome biogenesis and Activator. His VAV1 research entails a greater understanding of T cell.

Xosé R. Bustelo combines subjects such as Pathogenesis, VAV2, Metastasis, Regulation of gene expression and PI3K/AKT/mTOR pathway with his study of Cancer research. His MAPK/ERK pathway research incorporates themes from Computational biology and Protein–protein interaction. His GTPase study frequently draws connections to other fields, such as Cancer cell.

Between 2017 and 2021, his most popular works were:

  • CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets. (31 citations)
  • RHO GTPases in cancer: known facts, open questions, and therapeutic challenges. (28 citations)
  • Ribosome biogenesis and cancer: basic and translational challenges (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His main research concerns Cell biology, MAPK/ERK pathway, Computational biology, Protein–protein interaction and Kinase. The various areas that he examines in his Cell biology study include Antigen, Affinity maturation and CD40. Xosé R. Bustelo conducts interdisciplinary study in the fields of MAPK/ERK pathway and Anti-Tumor Drugs through his works.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

Z Songyang;S E Shoelson;J McGlade;P Olivier.
Molecular and Cellular Biology (1994)

1141 Citations

S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells

Wolf-Dietrich Hardt;Li-Mei Chen;Kornel E Schuebel;Xosé R Bustelo.
Cell (1998)

984 Citations

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

Piero Crespo;Piero Crespo;Kornel E. Schuebel;Amy A. Ostrom;J. Silvio Gutkind.
Nature (1997)

927 Citations

GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

Xosé R. Bustelo;Vincent Sauzeau;Inmaculada M. Berenjeno.
BioEssays (2007)

777 Citations

Regulatory and Signaling Properties of the Vav Family

Xosé R. Bustelo.
Molecular and Cellular Biology (2000)

609 Citations

Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

Akhilesh Pandey;Alexandre V. Podtelejnikov;Blagoy Blagoev;Xosé R. Bustelo.
Proceedings of the National Academy of Sciences of the United States of America (2000)

534 Citations

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

Xosé R. Bustelo;Jeffrey A. Ledbetter;Mariano Barbacid.
Nature (1992)

327 Citations

Phosphorylation‐dependent and constitutive activation of Rho proteins by wild‐type and oncogenic Vav‐2

Kornel E. Schuebel;Nieves Movilla;José Luis Rosa;Xosé R. Bustelo.
The EMBO Journal (1998)

295 Citations

Biological and Regulatory Properties of Vav-3, a New Member of the Vav Family of Oncoproteins

Nieves Movilla;Xosé R. Bustelo.
Molecular and Cellular Biology (1999)

294 Citations

Vav proteins, adaptors and cell signaling.

Xosé R Bustelo.
Oncogene (2001)

242 Citations

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