What is he best known for?
The fields of study he is best known for:
Cell biology, Signal transduction, Cancer research, G protein-coupled receptor and Protein kinase B are his primary areas of study. His Cell biology research includes themes of Semaphorin, Biochemistry and Angiogenesis. His Signal transduction research incorporates themes from Carcinogenesis, Kaposi's sarcoma-associated herpesvirus and GTPase.
His Cancer research research integrates issues from Cancer, Tumor progression, Wnt signaling pathway, Head and neck squamous-cell carcinoma and Immunology. J. Silvio Gutkind has researched G protein-coupled receptor in several fields, including Rhodopsin-like receptors, Neuroscience and G protein. The study incorporates disciplines such as Cell signaling and Cell growth in addition to PI3K/AKT/mTOR pathway.
His most cited work include:
- The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway (1508 citations)
- Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. (1306 citations)
- G-protein-coupled receptors and cancer. (959 citations)
What are the main themes of his work throughout his whole career to date?
J. Silvio Gutkind mainly focuses on Cancer research, Cell biology, Signal transduction, Cancer and PI3K/AKT/mTOR pathway. His studies in Cancer research integrate themes in fields like Cell, Carcinogenesis, Head and neck squamous-cell carcinoma, Immunology and Pathology. His Head and neck squamous-cell carcinoma study combines topics from a wide range of disciplines, such as Cancer cell, Immune system, Immunotherapy and Oncology.
The concepts of his Cell biology study are interwoven with issues in Receptor and Biochemistry. His research in Signal transduction intersects with topics in GTPase, Angiogenesis and Phosphorylation. His PI3K/AKT/mTOR pathway research includes elements of Tumor suppressor gene, Protein kinase B, Head and neck cancer and Sirolimus.
He most often published in these fields:
- Cancer research (39.59%)
- Cell biology (36.12%)
- Signal transduction (23.47%)
What were the highlights of his more recent work (between 2018-2021)?
- Cancer research (39.59%)
- Head and neck squamous-cell carcinoma (15.10%)
- Cell biology (36.12%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cancer research, Head and neck squamous-cell carcinoma, Cell biology, Cancer and Immunotherapy. J. Silvio Gutkind has included themes like Cell, Tumor microenvironment, Carcinogenesis and PI3K/AKT/mTOR pathway, Signal transduction in his Cancer research study. J. Silvio Gutkind is interested in Focal adhesion, which is a branch of Signal transduction.
His work carried out in the field of Head and neck squamous-cell carcinoma brings together such families of science as Cancer cell, Blockade, Cetuximab and Immune system. His is doing research in Heterotrimeric G protein, G protein-coupled receptor, Effector, G protein and Cell signaling, both of which are found in Cell biology. The various areas that he examines in his Cancer study include Melanoma, Computational biology and Gene.
Between 2018 and 2021, his most popular works were:
- Illuminating G-Protein-Coupling Selectivity of GPCRs. (122 citations)
- A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK. (70 citations)
- Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy (48 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Cancer research, Head and neck squamous-cell carcinoma, Receptor, Cell biology and Signal transduction. His Cancer research research is multidisciplinary, relying on both Cell, Cell growth, Gene knockdown, Farnesyltransferase and HRAS. His Head and neck squamous-cell carcinoma research is multidisciplinary, incorporating perspectives in Tumor microenvironment and Immune system.
His research integrates issues of Biophysics, PDZ domain, Gene and Docking in his study of Receptor. His work on Cell biology is being expanded to include thematically relevant topics such as Tube formation. His Signal transduction study frequently links to adjacent areas such as Carcinogenesis.
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