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J. Silvio Gutkind

D-Index & Metrics

Biology and Biochemistry

D-Index
139
Citations
71432
World Ranking
283
National Ranking
191

Medicine

D-Index
138
Citations
70616
World Ranking
1832
National Ranking
1046

J. Silvio Gutkind publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where J. Silvio Gutkind sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 577 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

J. Silvio Gutkind D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where J. Silvio Gutkind sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 139 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

J. Silvio Gutkind is affiliated with the University of California, San Diego, in the United States. Their research spans multiple fields within the life sciences, with a strong emphasis on biochemistry, genetics, and molecular biology, as well as medicine.

The scientist has a substantial publication record across various specialized topics including:

  • Cancer Immunotherapy and Biomarkers
  • Hippo pathway signaling and YAP/TAZ
  • Immunotherapy and Immune Responses
  • Receptor Mechanisms and Signaling
  • Ubiquitin and proteasome pathways
  • PI3K/AKT/mTOR signaling in cancer
  • Cancer-related gene regulation

Their research contributions have been published in several prominent venues. The most frequent publication outlets include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research
  • Nature Communications
  • International Journal of Radiation Oncology*Biology*Physics

Among their recent papers are:

  • "B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade" (2020), Clinical Cancer Research
  • "Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC" (2022), Nature Communications
  • "G Protein-Coupled receptors and heterotrimeric G proteins as cancer drivers" (2020), FEBS Letters
  • "Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer" (2022), Nature Communications
  • "Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas" (2020), Molecular Cancer Therapeutics

Collaborations are a notable part of their work, with frequent coauthors including:

  • Zhiyong Wang
  • Robert Saddawi-Konefka
  • Joseph A. Califano
  • Alfredo Molinolo
  • Ezra E.W. Cohen

Gutkind's subfields of study highlight a multidisciplinary approach, with significant involvement in:

  • Molecular Biology
  • Oncology
  • Cell Biology
  • Immunology
  • Pulmonary and Respiratory Medicine

Best Publications

  • The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

    Omar A. Coso;Mario Chiariello;Jin-Chen Yu;Hidemi Teramoto

  • Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate.

    Olivier Cuvillier;Grisha Pirianov;Burkhard Kleuser;Philip G. Vanek

  • G-protein-coupled receptors and cancer.

    Robert T. Dorsam;J. Silvio Gutkind

  • Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

    S Miyamoto;H Teramoto;O A Coso;J S Gutkind

  • G-protein-coupled receptors and signaling networks: emerging paradigms.

    Maria Julia Marinissen;J.Silvio Gutkind

  • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin.

    Julie Gavard;J. Silvio Gutkind

  • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

    Maria Domenica Castellone;Hidemi Teramoto;Bart O. Williams;Kirk M. Druey

  • Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits

    P. Crespo;Ningzhi Xu;W. F. Simonds;J. S. Gutkind

  • G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

    Carlos Bais;Bianca Santomasso;Omar Coso;Leandros Arvanitakis;Leandros Arvanitakis

  • Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery.

    Ashwin A. Bhirde;Vyomesh Patel;Julie Gavard;Guofeng Zhang

  • Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors.

    S Miyamoto;H Teramoto;J S Gutkind;K M Yamada

  • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

    Piero Crespo;Piero Crespo;Kornel E. Schuebel;Amy A. Ostrom;J. Silvio Gutkind

  • Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ

    Marco Lopez-Ilasaca;Piero Crespo;P. Giuseppe Pellici;J. Silvio Gutkind

  • Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging

    Hongjun Liu;Maria M Fergusson;Rogerio M. Castilho;Jie Liu

  • Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers.

    Xin Yu;Bernard Munge;Vyomesh Patel;Gary Jensen

  • G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension.

    Angela Wirth;Zoltán Benyó;Zoltán Benyó;Martina Lukasova;Barbara Leutgeb;Barbara Leutgeb

  • Cbl-b regulates the CD28 dependence of T-cell activation

    Yungping J. Chiang;Hemanta K. Kole;Karen Brown;Mayumi Naramura

  • Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

    James F. Rusling;James F. Rusling;James F. Rusling;Challa V. Kumar;J. Silvio Gutkind;Vyomesh Patel

  • The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer

    Morgan O'Hayre;José Vázquez-Prado;Irina Kufareva;Eric W. Stawiski

  • Ultrasensitive Immunosensor for Cancer Biomarker Proteins using Gold Nanoparticle Film Electrodes and Multienzyme-Particle Amplification

    Vigneshwaran Mani;Bhaskara V. Chikkaveeraiah;Vyomesh Patel;J. Silvio Gutkind

Frequent Co-Authors

Alfredo A. Molinolo
Alfredo A. Molinolo University of California, San Diego
James F. Rusling
James F. Rusling University of Connecticut
Joseph A. Califano
Joseph A. Califano University of California, San Diego
Qianming Chen
Qianming Chen Sichuan University
Julie Gavard
Julie Gavard University of Nantes
Asuka Inoue
Asuka Inoue Tohoku University
Shigetomo Fukuhara
Shigetomo Fukuhara Nippon Medical School
Thomas H. Bugge
Thomas H. Bugge National Institutes of Health
Scott M. Lippman
Scott M. Lippman University of California, San Diego
Piero Crespo
Piero Crespo Spanish National Research Council

External Links

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These online programs offer a flexible and accessible way to prepare for diverse careers, whether your goal is front-line patient care, scientific research, or healthcare leadership.

Best Scientists Citing J. Silvio Gutkind

Stefan Offermanns

Stefan Offermanns

Max Planck Society

Publications: 148

Sarah Spiegel

Sarah Spiegel

Virginia Commonwealth University

Publications: 109

James F. Rusling

James F. Rusling

University of Connecticut

Publications: 83

Sheldon Milstien

Sheldon Milstien

Virginia Commonwealth University

Publications: 61

Thomas H. Bugge

Thomas H. Bugge

National Institutes of Health

Publications: 60

Julie Gavard

Julie Gavard

University of Nantes

Publications: 58

Josef M. Penninger

Josef M. Penninger

University of British Columbia

Publications: 58

Jennifer R. Grandis

Jennifer R. Grandis

University of California, San Francisco

Publications: 55

Xosé R. Bustelo

Xosé R. Bustelo

University of Salamanca

Publications: 54

Huangxian Ju

Huangxian Ju

Nanjing University

Publications: 52

Channing J. Der

Channing J. Der

University of North Carolina at Chapel Hill

Publications: 48

Martine J. Smit

Martine J. Smit

Vrije Universiteit Amsterdam

Publications: 45

Lina M. Obeid

Lina M. Obeid

Stony Brook University

Publications: 44

Asuka Inoue

Asuka Inoue

Tohoku University

Publications: 44

Jonathan Chernoff

Jonathan Chernoff

Fox Chase Cancer Center

Publications: 43

Husseini K. Manji

Husseini K. Manji

National Institutes of Health

Publications: 41

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Oguz Okay

Oguz Okay

Istanbul Technical University

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Sebastián Feliu

Spanish National Research Council

Eric R. Morgan

Eric R. Morgan

Queen's University Belfast

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Georges Pelletier

INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement

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Elena Paoletti

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