World's Best Scientists 2026 revealed!
Award Badge
Best Scientists
2025
Award Badge
Biology and Biochemistry
Canada
2026

D-Index & Metrics

Best Scientists

D-Index
184
Citations
162560
World Ranking
519
National Ranking
12

Biology and Biochemistry

D-Index
185
Citations
169041
World Ranking
60
National Ranking
3

Medicine

D-Index
188
Citations
170724
World Ranking
271
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2026 - Research.com Medicine in Canada Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2025 - Research.com Medicine in Canada Leader Award
  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2023 - Research.com Medicine in Canada Leader Award
  • 2022 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2014 - Wittgenstein Award
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2009 - Member of Academia Europaea
  • 2004 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Academy of Sciences and Arts
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Josef M. Penninger is affiliated with the University of British Columbia in Canada. Their research spans multiple disciplines, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these broad fields, their work delves into molecular biology, infectious diseases, immunology, neurology, and oncology.

The scientist has contributed extensively to research on SARS-CoV-2 and COVID-19, including clinical research studies and investigations into the long-term effects of COVID-19. Other significant topics in their work include glycosylation and glycoproteins research, RNA modifications and cancer, RNA research and splicing, as well as pain mechanisms and treatments.

Recent notable publications by Josef M. Penninger include:

  • Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target, 2020, Intensive Care Medicine
  • Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2, 2020, Cell
  • Autophagy in major human diseases, 2021, The EMBO Journal
  • Human recombinant soluble ACE2 in severe COVID-19, 2020, The Lancet Respiratory Medicine
  • Ferritinophagy and ferroptosis in the management of metabolic diseases, 2021, Trends in Endocrinology and Metabolism

Their frequent co-authors include Astrid Hagelkrüys, Alì Mirazimi, Vanessa Monteil, Shane J. F. Cronin, and Gerald Wirnsberger. Josef M. Penninger has published prolifically in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cell, EMBO Molecular Medicine, and Scientific Reports.

Josef M. Penninger's contributions to science have been recognized through various awards and memberships. They received the Wittgenstein Award in 2014 and were named a Fellow of the American Association for the Advancement of Science in 2011. They became a member of Academia Europaea in 2009 and joined the German National Academy of Sciences Leopoldina in 2004 for contributions in microbiology and immunology. Additionally, they hold membership in the European Academy of Sciences and Arts and the European Molecular Biology Organization (EMBO).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Molecular characterization of mitochondrial apoptosis-inducing factor

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Cerebral organoids model human brain development and microcephaly

    Madeline A. Lancaster;Magdalena Renner;Carol Anne Martin;Daniel Wenzel

  • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

    Young-Yun Kong;Hiroki Yoshida;Ildiko Sarosi;Hong-Lin Tan

  • A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

    Keiji Kuba;Yumiko Imai;Shuan Rao;Hong Gao

  • Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4

    Paul Waterhouse;Josef M. Penninger;Emma Timms;Andrew Wakeham

  • Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

    Vuk Stambolic;Vuk Stambolic;Akira Suzuki;Akira Suzuki;José Luis de la Pompa;José Luis de la Pompa

  • Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.

    Haibo Zhang;Haibo Zhang;Haibo Zhang;Josef M. Penninger;Josef M. Penninger;Yimin Li;Nanshan Zhong

  • Angiotensin-converting enzyme 2 protects from severe acute lung failure

    Yumiko Imai;Keiji Kuba;Shuan Rao;Yi Huan

  • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

    Young-Yun Kong;Ulrich Feige;Iidiko Sarosi;Brad Bolon

  • Angiotensin-converting enzyme 2 is an essential regulator of heart function

    Michael A. Crackower;Renu Sarao;Renu Sarao;Gavin Y. Oudit;Gavin Y. Oudit;Chana Yagil

  • Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.

    Vanessa Monteil;Hyesoo Kwon;Patricia Prado;Astrid Hagelkrüys

  • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

    Nicholas Joza;Nicholas Joza;Santos A. Susin;Eric Daugas;William L. Stanford

  • Evidence for osteocyte regulation of bone homeostasis through RANKL expression

    Tomoki Nakashima;Mikihito Hayashi;Takanobu Fukunaga;Kosaku Kurata

  • Mitogen-activated protein kinases in apoptosis regulation.

    Teiji Wada;Josef M Penninger

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Differential requirement for caspase 9 in apoptotic pathways in vivo

    Razqallah Hakem;Razqallah Hakem;Anne Hakem;Anne Hakem;Gordon S Duncan;Gordon S Duncan;Jeffrey T Henderson

  • Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

    Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami

  • TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

    Mark A. Lomaga;Wen Chen Yeh;Ildiko Sarosi;Gordon S. Duncan

Frequent Co-Authors

Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Gavin Y. Oudit
Gavin Y. Oudit University of Alberta
Guido Kroemer
Guido Kroemer Université Paris Cité
Takehiko Sasaki
Takehiko Sasaki Tokyo Medical and Dental University
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
John C. Roder
John C. Roder University of Toronto
Janet Rossant
Janet Rossant University of Toronto
Hiroshi Nishina
Hiroshi Nishina Tokyo Medical and Dental University
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Josef M. Penninger

Trending Scientists

Recently Published Articles