Emilio Hirsch mostly deals with Cell biology, PI3K/AKT/mTOR pathway, Immunology, Internal medicine and Signal transduction. His Cell biology study combines topics from a wide range of disciplines, such as Integrin and Cellular differentiation. His PI3K/AKT/mTOR pathway research is multidisciplinary, incorporating elements of Receptor, Receptor tyrosine kinase, T-cell receptor, Synapse and Phosphatidylinositol.
His biological study spans a wide range of topics, including Cancer and Cancer research. His work is dedicated to discovering how Internal medicine, Endocrinology are connected with Protein kinase B and other disciplines. His Signal transduction study combines topics in areas such as Muscle hypertrophy, Insulin receptor and Phosphorylation.
His primary areas of study are Cell biology, Internal medicine, PI3K/AKT/mTOR pathway, Signal transduction and Immunology. Emilio Hirsch interconnects Receptor and Integrin in the investigation of issues within Cell biology. His Internal medicine study incorporates themes from Endocrinology and Cardiology.
Emilio Hirsch combines subjects such as Cardiac function curve and Phosphodiesterase with his study of Endocrinology. His study explores the link between PI3K/AKT/mTOR pathway and topics such as Cancer research that cross with problems in Pancreatic cancer. His is doing research in Inflammation, Immune system and Chemokine, both of which are found in Immunology.
His primary scientific interests are in Cell biology, Cancer research, PI3K/AKT/mTOR pathway, Internal medicine and Inflammation. His study brings together the fields of Enzyme and Cell biology. His PI3K/AKT/mTOR pathway research is multidisciplinary, incorporating elements of Cell, Protein kinase B, Disease, Kinase and Gene isoform.
The various areas that he examines in his Internal medicine study include Endocrinology and Cardiology. His Inflammation research is multidisciplinary, incorporating perspectives in Diabetes mellitus, Fibrosis, Pulmonary fibrosis, Pharmacology and In vivo. His research integrates issues of Immunology and Phosphorylation in his study of Signal transduction.
The scientist’s investigation covers issues in Cell biology, PI3K/AKT/mTOR pathway, Signal transduction, Cancer and Phosphorylation. His study looks at the relationship between Cell biology and topics such as Enzyme, which overlap with Gene isoform. The study incorporates disciplines such as Disease and Second messenger system in addition to PI3K/AKT/mTOR pathway.
He focuses mostly in the field of Second messenger system, narrowing it down to topics relating to Protein kinase B and, in certain cases, Kinase. His studies deal with areas such as Regulator, Cofilin, Actin cytoskeleton and Hyperphosphorylation as well as Signal transduction. The concepts of his Genetically modified mouse study are interwoven with issues in Endocrinology and Internal medicine.
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Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation
Emilio Hirsch;Vladimir L. Katanaev;Cecilia Garlanda;Ornella Azzolino.
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
Montserrat Camps;Thomas Rückle;Hong Ji;Vittoria Ardissone.
Nature Medicine (2005)
PI3K/AKT signaling pathway and cancer: an updated review.
Miriam Martini;Maria Chiara De Santis;Laura Braccini;Federico Gulluni.
Annals of Medicine (2014)
Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways
Michael A. Crackower;Gavin Y. Oudit;Ivona Kozieradzki;Ivona Kozieradzki;Renu Sarao;Renu Sarao.
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response
Cecilia Garlanda;Emilio Hirsch;Silvia Bozza;Antonietta Salustri.
PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects
Enrico Patrucco;Antonella Notte;Laura Barberis;Giulio Selvetella.
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.
Antonietta Salustri;Cecilia Garlanda;Emilio Hirsch;Marika De Acetis.
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.
Thomas Eschenhagen;Thomas Force;Michael S. Ewer;Gilles W. De Keulenaer.
European Journal of Heart Failure (2011)
Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins.
Emilio Hirsch;Antonio Iglesias;Alexandra J. Potocnik;Ursula Hartmann.
Phosphoinositide 3-Kinase γ Is an Essential Amplifier of Mast Cell Function
Muriel Laffargue;Ronan Calvez;Peter Finan;Alexandre Trifilieff.
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