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Bernard Payrastre

Bernard Payrastre

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
20688
World Ranking
3753
National Ranking
95

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Bernard Payrastre is a researcher affiliated with Inserm in France, with a substantial body of work centered in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans subfields such as Molecular Biology, Hematology, Cell Biology, Epidemiology, and Infectious Diseases.

Their investigations focus on key topics including Platelet Disorders and Treatments, Cellular transport and secretion, Venous Thromboembolism Diagnosis and Management, Pancreatic function and diabetes, Erythrocyte Function and Pathophysiology, COVID-19 Clinical Research Studies, and Blood properties and coagulation.

Payrastre has contributed to multiple peer-reviewed papers published across various scientific journals. Recent papers include:

  • Thromboembolic events and Covid-19, 2020, Advances in Biological Regulation
  • Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation, 2020, Cell Reports
  • Strengths and Weaknesses of Light Transmission Aggregometry in Diagnosing Hereditary Platelet Function Disorders, 2020, Journal of Clinical Medicine
  • Dysregulation of myelin synthesis and actomyosin function underlies aberrant myelin in CMT4B1 neuropathy, 2021, Proceedings of the National Academy of Sciences
  • Platelet activation and partial desensitization are associated with viral xenophagy in patients with severe COVID-19, 2022, Blood Advances

These publications illustrate a focus on hematological disorders and infectious disease interactions, particularly studied through cellular and molecular mechanisms.

Payrastre frequently collaborates with a number of researchers, including:

  • Gaëtan Chicanne
  • Cédric Garcia
  • Agnès Ribes
  • Julien Viaud
  • Marie-Pierre Gratacap

Their work appears regularly in several established scientific journals such as:

  • Research and Practice in Thrombosis and Haemostasis
  • Advances in Biological Regulation
  • Platelets
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Methods in molecular biology

Best Publications

  • Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

    Georgine Agullo;Laurence Gamet-Payrastre;Stéphane Manenti;Cécile Viala

  • The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

    Or Gozani;Philip Karuman;David R. Jones;Dmitri Ivanov

  • Conversion of PtdIns(4,5)P2 into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

    Kirsten Niebuhr;Sylvie Giuriato;Thierry Pedron;Dana J. Philpott

  • Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

    Maud de Saint-Jean;Vanessa Delfosse;Dominique Douguet;Gaëtan Chicanne

  • Antileukemic activity of rapamycin in acute myeloid leukemia.

    Christian Récher;Odile Beyne-Rauzy;Cécile Demur;Gaëtan Chicanne

  • A role for phosphoinositide 3-kinase in bacterial invasion.

    Keith Ireton;Bernard Payrastre;Hugues Chap;Wataru Ogawa

  • A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix.

    B. Payrastre;M. Nievers;J. Boonstra;M. Breton

  • Flavonoids and the inhibition of PKC and PI 3-kinase.

    Laurence Gamet-Payrastre;Stéphane Manenti;Marie-Pierre Gratacap;Jacques Tulliez

  • Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation

    Rémi Lasserre;Xiao-Jun Guo;Fabien Conchonaud;Fabien Conchonaud;Yannick Hamon;Yannick Hamon

  • Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions

    Marie Levade;Elodie David;Cédric Garcia;Pierre-Alexandre Laurent

  • Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase.

    C Guinebault;B Payrastre;C Racaud-Sultan;H Mazarguil

  • A Key Role of Adenosine Diphosphate in the Irreversible Platelet Aggregation Induced by the PAR1-Activating Peptide Through the Late Activation of Phosphoinositide 3-Kinase

    Catherine Trumel;Bernard Payrastre;Monique Plantavid;Béatrice Hechler

  • Phosphoinositides: key players in cell signalling, in time and space.

    Bernard Payrastre;Karine Missy;Sylvie Giuriato;Stéphane Bodin

  • Phosphoinositide signaling disorders in human diseases.

    Caroline Pendaries;Hélène Tronchère;Monique Plantavid;Bernard Payrastre

  • PtdIns(5)P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection

    Caroline Pendaries;Hélène Tronchère;Laurence Arbibe;Joelle Mounier

  • Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

    François Blondeau;Jocelyn Laporte;Stephane Bodin;Giulio Superti-Furga

  • Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor.

    B Payrastre;P M P Van Bergen En Henegouwen;M Breton;J C Den Hartigh

  • Constitutive Macropinocytosis in Oncogene-transformed Fibroblasts Depends on Sequential Permanent Activation of Phosphoinositide 3-Kinase and Phospholipase C

    Mustapha Amyere;Bernard Payrastre;Ulrike Krause;Patrick Van Der Smissen

  • Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis.

    L. Ysebaert;G. Chicanne;C. Demur;F. De Toni

  • Origin, originality, functions, subversions and molecular signalling of macropinocytosis

    Mustapha Amyere;Marcel Mettlen;Patrick Van Der Smissen;Anna Platek

Frequent Co-Authors

Hugues Chap
Hugues Chap Grenoble Alpes University
Christian Recher
Christian Recher Federal University of Toulouse Midi-Pyrénées
Georges Delsol
Georges Delsol Federal University of Toulouse Midi-Pyrénées
Philippe J. Sansonetti
Philippe J. Sansonetti Institut Pasteur
Bart Vanhaesebroeck
Bart Vanhaesebroeck University College London
Christophe Erneux
Christophe Erneux Université Libre de Bruxelles
Pascale Cossart
Pascale Cossart Institut Pasteur
Christian Gachet
Christian Gachet University of Strasbourg
Jean-Louis Mandel
Jean-Louis Mandel Institute of Genetics and Molecular and Cellular Biology
Odile Burlet-Schiltz
Odile Burlet-Schiltz Federal University of Toulouse Midi-Pyrénées

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