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Biology and Biochemistry

D-Index
64
Citations
10812
World Ranking
9916
National Ranking
177

Overview

Christophe Erneux is affiliated with the Université Libre de Bruxelles in Belgium. Their research spans across several domains within biochemistry, genetics, molecular biology, and medicine, with notable contributions in subfields such as molecular biology, cell biology, physiology, immunology, and pulmonary and respiratory medicine.

The main topics that Christophe Erneux has focused on during their academic career include:

  • Alzheimer's disease research and treatments
  • Cellular transport and secretion
  • Protein Kinase Regulation and GTPase Signaling
  • Renal Diseases and Glomerulopathies
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Complement system in diseases
  • Neuroscience and Neuropharmacology Research

Their research output features studies published in various scientific venues. Frequent publication venues include:

  • Cell Reports
  • Frontiers in Molecular Neuroscience
  • Cancers
  • Frontiers in Neuroscience
  • Acta Neuropathologica

Recent papers authored or co-authored by Christophe Erneux are as follows:

  • APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin (2020) in Cell Reports
  • Alzheimer's Disease: Tau Pathology and Dysfunction of Endocytosis (2021) in Frontiers in Molecular Neuroscience
  • Ferroptosis Induction and YAP Inhibition as New Therapeutic Targets in Gastrointestinal Stromal Tumors (GISTs) (2022) in Cancers
  • Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease (2021) in Frontiers in Neuroscience
  • Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer's disease pathology progression (2024) in Acta Neuropathologica

Christophe Erneux has collaborated frequently with several co-authors:

  • Ana Raquel Ramos
  • Kunié Ando
  • Jean-Pierre Brion
  • Karelle Leroy
  • Tomas Luyten

Best Publications

  • The lipid phosphatase SHIP2 controls insulin sensitivity

    Serge Clément;Ulrike Krause;Florence Desmedt;Jean-François Tanti

  • IDENTIFICATION OF A SECOND SH2-DOMAIN-CONTAINING PROTEIN CLOSELY RELATED TO THE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE SHIP

    Xavier Pesesse;Sandrine Deleu;Florence De Smedt;Lyndsay Drayer

  • Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression.

    Marily Theodoropoulou;Jing Zhang;Sandra Laupheimer;Marcelo Paez-Pereda

  • Involvement of inositol 1,4,5-trisphosphate and calcium in the action of adenine nucleotides on aortic endothelial cells.

    Sabine Pirotton;Eric Raspé;Dominique Demolle;Christophe Erneux

  • The diversity and possible functions of the inositol polyphosphate 5-phosphatases.

    Christophe Erneux;Cédric Govaerts;David Communi;Xavier Pesesse

  • A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).

    Erika Rosivatz;Jonathan G. Matthews;Neil Q. McDonald;Neil Q. McDonald;Xavier Mulet

  • Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminus.

    Michael J. Schell;Christophe Erneux;Robin F. Irvine

  • The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells.

    Christophe Erneux;S Cohen;D L Garbers

  • Xestospongin C is an equally potent inhibitor of the inositol 1,4,5-trisphosphate receptor and the endoplasmic-reticulum Ca(2+) pumps.

    P De Smet;Jb Parys;G Callewaert;Af Weidema

  • Distribution of the src-homology-2-domain-containing inositol 5-phosphatase SHIP-2 in both non-haemopoietic and haemopoietic cells and possible involvement of SHIP-2 in negative signalling of B-cells.

    Eric Muraille;Xavier Pesesse;Céline Kuntz;Christophe Erneux

  • The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity

    Xavier Pesesse;Colette Moreau;A.Lyndsay Drayer;Rüdiger Woscholski;Rüdiger Woscholski

  • Chemoattractant and guanosine 5'-[gamma-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in Dictyostelium cells that are labelled with [3H]inositol by electroporation.

    P J M Van Haastert;M J De Vries;L C Penning;E Roovers

  • Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development.

    Valérie Pouillon;Romana Hascakova-Bartova;Bernard Pajak;Emmanuelle Adam

  • The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases.

    Katrien Backers;Daniel Blero;Nathalie Paternotte;Jing Zhang

  • Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets.

    Sylvie Giuriato;Bernard Payrastre;Anneke Lyndsay Drayer;M Plantavid

  • The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells.

    Xavier Pesesse;Valérie Dewaste;Florence De Smedt;Muriel Laffargue

  • Simulations of the effects of inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase activities on Ca2+ oscillations.

    Geneviève Dupont;Christophe Erneux

  • Specificity of Cyclic GMP Activation of a Multi-substrate Cyclic Nucleotide Phosphodiesterase from Rat Liver

    Christophe Erneux;Dominique Couchie;Jacques E. Dumont;Janina Baraniak

  • Phosphoinositide phosphatases in a network of signalling reactions

    Daniel Blero;Bernard Payrastre;Stéphane Schurmans;Christophe Erneux

  • Rat brain inositol 1,4,5-trisphosphate 3-kinase. Ca2(+)-sensitivity, purification and antibody production.

    Kazunaga Takazawa;Manuela Lemos;Anne Delvaux;Christophe Lejeune

Frequent Co-Authors

Jacques Emile Dumont
Jacques Emile Dumont Université Libre de Bruxelles
Jean-Marie Boeynaems
Jean-Marie Boeynaems Université Libre de Bruxelles
Barry V. L. Potter
Barry V. L. Potter University of Oxford
Bernd Jastorff
Bernd Jastorff University of Bremen
Peter J.M. van Haastert
Peter J.M. van Haastert University of Groningen
Takehiko Sasaki
Takehiko Sasaki Tokyo Medical and Dental University
Jan B. Parys
Jan B. Parys KU Leuven
Serge N. Schiffmann
Serge N. Schiffmann Université Libre de Bruxelles

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