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Ludwig Missiaen

Ludwig Missiaen

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Biology and Biochemistry
Belgium
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
21511
World Ranking
4546
National Ranking
74

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

Ludwig Missiaen is affiliated with KU Leuven in Belgium and focuses research efforts on areas spanning pharmacology, toxicology, pharmaceutics, medicine, and biochemistry, genetics, and molecular biology. Their work integrates these disciplines to address complex biomedical questions related to drug metabolism, genetic diseases, and cellular mechanisms.

Their recent scholarly contributions include two papers: "CYP2D6 polymorphism may contribute to Trazodone-induced hepatotoxicity: a rare case of drug-drug-gene induced liver injury" (2024, Acta Gastro Enterologica Belgica) and "The molecular landscape of polycystic kidneys is marked by common alterations in purine metabolism" (2025, bioRxiv (Cold Spring Harbor Laboratory)).

Research themes in Missiaen's work focus notably on:

  • Drug-Induced Hepatotoxicity and Protection
  • Pharmacogenetics and Drug Metabolism
  • Drug Transport and Resistance Mechanisms
  • Genetic and Kidney Cyst Diseases
  • Renal and related cancers
  • Pediatric Urology and Nephrology Studies

Missiaen collaborates frequently with several colleagues, including:

  • K Ferdinande
  • L. DeClerck
  • Cristina Melis
  • L Seynhaeve
  • C De Vloo

Publications appear most often in the following venues:

  • Acta Gastro Enterologica Belgica
  • bioRxiv (Cold Spring Harbor Laboratory)

Fields of study encompass:

  • Pharmacology, Toxicology and Pharmaceutics
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specific subfields include:

  • Pharmacology
  • Oncology
  • Genetics
  • Molecular Biology
  • Pediatrics, Perinatology and Child Health

Best Publications

  • Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+.

    M D Bootman;L Missiaen;J B Parys;H De Smedt

  • Endoplasmic-Reticulum Calcium Depletion and Disease

    Djalila Mekahli;Geert Bultynck;Jan B. Parys;Humbert De Smedt

  • Molecular physiology of the SERCA and SPCA pumps

    Frank Wuytack;Luc Raeymaekers;Ludwig Missiaen

  • Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores

    Ludwig Missiaen;Colin W. Taylor;Michael J. Berridge

  • Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells

    Ludwig Missiaen;Humbert De Smedt;Guillaume Droogmans;Rik Casteels

  • Abnormal intracellular ca(2+)homeostasis and disease.

    L. Missiaen;W. Robberecht;L.Van Den Bosch;G. Callewaert

  • Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy

    Esther Buytaert;Geert Callewaert;Nico Hendrickx;Luca Scorrano

  • 2-Aminoethoxydiphenyl borate affects the inositol 1,4,5-trisphosphate receptor, the intracellular Ca2+pump and the non-specific Ca2+leak from the non-mitochondrial Ca2+stores in permeabilized A7r5 cells

    L. Missiaen;G. Callewaert;H. De Smedt;J.B. Parys

  • Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction

    H De Smedt;L Missiaen;J B Parys;M D Bootman

  • Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.

    Veerle Vanderheyden;Benoit Devogelaere;Ludwig Missiaen;Humbert De Smedt

  • Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.

    Eva Sammels;Jan B. Parys;Ludwig Missiaen;Humbert De Smedt

  • The IP(3) receptor-mitochondria connection in apoptosis and autophagy.

    Jean-Paul Decuypere;Giovanni Monaco;Geert Bultynck;Ludwig Missiaen

  • Expression and function of ryanodine receptors in nonexcitable cells.

    Deborah L. Bennett;Timothy R. Cheek;Michael J. Berridge;Humbert De Smedt

  • Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

    Jean-Paul Decuypere;Kirsten Welkenhuyzen;Tomas Luyten;Raf Ponsaerts

  • Deletion of the ryanodine receptor type 3 (RyR3) impairs forms of synaptic plasticity and spatial learning

    Detlef Balschun;David P. Wolfer;Federica Bertocchini;Virginia Barone

  • Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.

    Nael Nadif Kasri;Anthony M Holmes;Geert Bultynck;Jan B Parys

  • Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival☆

    Hristina Ivanova;Tim Vervliet;Ludwig Missiaen;Jan B. Parys

  • Molecular and Functional Evidence for Multiple Ca2+-binding Domains in the Type 1 Inositol 1,4,5-Trisphosphate Receptor

    Ilse Sienaert;Ludwig Missiaen;Humbert De Smedt;Jan B. Parys

  • Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

    G Monaco;Elke Decrock;H Akl;Raf Ponsaerts

  • Caspase-3-induced Truncation of Type 1 Inositol Trisphosphate Receptor Accelerates Apoptotic Cell Death and Induces Inositol Trisphosphate-independent Calcium Release during Apoptosis

    Zerihun Assefa;Geert Bultynck;Karolina Szlufcik;Nael Nadif Kasri

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