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D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
56650
World Ranking
3409
National Ranking
256

Overview

Martin D. Bootman is affiliated with The Open University in the United Kingdom. Their research focuses primarily on the field of Biochemistry, Genetics and Molecular Biology, with a specific emphasis on Molecular Biology, Physiology, Genetics, Plant Science, and Epidemiology as subfields of study.

The scientist's work encompasses several main topics, including:

  • Protein Kinase Regulation and GTPase Signaling
  • Ion channel regulation and function
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Genetics and Neurodevelopmental Disorders
  • Ion Channels and Receptors
  • Mitochondrial Function and Pathology

Recent papers by Martin D. Bootman include:

  • Calcium signalling pathways in prostate cancer initiation and progression, 2023, Nature Reviews Urology
  • Off-target inhibition of NGLY1 by the polycaspase inhibitor Z-VAD-fmk induces cellular autophagy, 2022, FEBS Journal
  • A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca2+ signalling through IP3 receptors, 2022, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Cellular effects of BAPTA: Are they only about Ca2+ chelation?, 2023, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells, 2023, Cell Death and Disease

Their frequent co-authors include:

  • Geert Bultynck (7 publications)
  • Fernanda O. Lemos (3 publications)
  • Martijn Kerkhofs (3 publications)
  • Jan B. Parys (3 publications)
  • Flore Sneyers (3 publications)

Martin D. Bootman has published multiple papers in various venues. The most frequent publication venues include:

  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • Nature Reviews Urology (1 publication)
  • FEBS Journal (1 publication)
  • Cell Death and Disease (1 publication)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • The versatility and universality of calcium signalling

    Michael J. Berridge;Peter Lipp;Martin D. Bootman

  • Calcium signalling: dynamics, homeostasis and remodelling

    Michael J. Berridge;Martin D. Bootman;H. Llewelyn Roderick

  • Calcium - a life and death signal

    Michael J. Berridge;Martin D. Bootman;Peter Lipp

  • Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+.

    M D Bootman;L Missiaen;J B Parys;H De Smedt

  • 2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release.

    Martin D. Bootman;Tony J. Collins;Lauren Mackenzie;H. Llewelyn Roderick

  • Calcium signalling—an overview

    Martin D Bootman;Tony J Collins;Claire M Peppiatt;Larissa S Prothero

  • Mitochondria are morphologically and functionally heterogeneous within cells

    Tony J. Collins;Michael J. Berridge;Peter Lipp;Martin D. Bootman;Martin D. Bootman

  • The elemental principles of calcium signaling.

    Martin D. Bootman;Michael J. Berridge

  • The organisation and functions of local Ca(2+) signals.

    Martin D. Bootman;Peter Lipp;Michael J. Berridge

  • Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate

    Rui-rui Chen;Ignacio Valencia;Fei Zhong;Karen S McColl

  • A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals.

    D. Thomas;S.C. Tovey;T.J. Collins;M.D. Bootman;M.D. Bootman

  • Cooking with Calcium: The Recipes for Composing Global Signals from Elementary Events

    Martin D Bootman;Martin D Bootman;Michael J Berridge;Peter Lipp

  • 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels

    Claire M. Peppiatt;Tony J. Collins;Lauren Mackenzie;Stuart J. Conway

  • Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells. A Potential Mechanism in Atherosclerotic Plaque Destabilization

    Alexandra E. Ewence;Martin D. Bootman;H. Llewelyn Roderick;Jeremy N. Skepper

  • Calcium signalling: more messengers, more channels, more complexity

    Martin D Bootman;Michael J Berridge;H.Llewelyn Roderick

  • Imaging the hierarchical Ca2+ signalling system in HeLa cells.

    Martin Bootman;Ernst Niggli;Michael Berridge;Peter Lipp

  • The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

    Yi Ping Rong;Geert Bultynck;Ademuyiwa S. Aromolaran;Fei Zhong

  • Calcium Signaling in Cardiac Myocytes

    Claire J. Fearnley;H. Llewelyn Roderick;Martin D. Bootman

  • The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.

    Martin D. Bootman;Colin W. Taylor;Michael J. Berridge

Frequent Co-Authors

Michael J. Berridge
Michael J. Berridge Babraham Institute
Jan B. Parys
Jan B. Parys KU Leuven
Andrew B. Holmes
Andrew B. Holmes University of Melbourne
Rik Casteels
Rik Casteels KU Leuven
Colin W. Taylor
Colin W. Taylor University of Cambridge
David D. Thomas
David D. Thomas University of Minnesota

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