World's Best Scientists 2026 revealed!
Rosario Rizzuto

Rosario Rizzuto

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Biology and Biochemistry
Italy
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
131
Citations
85797
World Ranking
385
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Italy Leader Award
  • 2025 - Research.com Biology and Biochemistry in Italy Leader Award
  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award
  • 2022 - Research.com Biology and Biochemistry in Italy Leader Award
  • 2009 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Mitochondrion

Rosario Rizzuto focuses on Cell biology, Mitochondrion, Calcium signaling, Cytosol and Endoplasmic reticulum. Rosario Rizzuto has researched Cell biology in several fields, including Apoptosis, Biochemistry and Programmed cell death. His Biochemistry research is multidisciplinary, relying on both Biophysics and Calcium.

His Mitochondrion research is multidisciplinary, incorporating elements of Mitochondrial matrix, Cytoplasm, Organelle and Voltage-dependent calcium channel. His research in Calcium signaling intersects with topics in Molecular biology and Cellular homeostasis. His Endoplasmic reticulum research includes elements of Membrane contact site and Chaperone.

His most cited work include:

  • Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca2+ Responses (1778 citations)
  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter (1257 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Mitochondrion, Calcium signaling, Endoplasmic reticulum and Biochemistry. His work deals with themes such as Apoptosis, Programmed cell death, Calcium and Cytosol, which intersect with Cell biology. His studies in Programmed cell death integrate themes in fields like Autophagy and Signal transduction.

The various areas that Rosario Rizzuto examines in his Mitochondrion study include Uniporter, Mitochondrial matrix, Organelle and Homeostasis. His Biochemistry research incorporates themes from Molecular biology and Skeletal muscle. In his research on the topic of Aequorin, Photoprotein is strongly related with Biophysics.

He most often published in these fields:

  • Cell biology (62.69%)
  • Mitochondrion (44.04%)
  • Calcium signaling (22.80%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (62.69%)
  • Mitochondrion (44.04%)
  • Skeletal muscle (8.03%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Mitochondrion, Skeletal muscle, Calcium and Homeostasis. His studies deal with areas such as Calcium metabolism and Mitochondrial calcium uptake as well as Cell biology. He interconnects Uniporter, Cytosol, Programmed cell death and Organelle in the investigation of issues within Mitochondrion.

His work carried out in the field of Cytosol brings together such families of science as Aequorin and Intracellular. Rosario Rizzuto combines subjects such as Autophagy and Neuroscience with his study of Programmed cell death. The concepts of his Calcium study are interwoven with issues in Biochemistry and Disease.

Between 2014 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (591 citations)
  • Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB (587 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Mitochondrion, Cell biology, Organelle, Calcium and Homeostasis are his primary areas of study. His Mitochondrion research is multidisciplinary, incorporating perspectives in Loss function, Protein subunit and Skeletal muscle. The study incorporates disciplines such as Oxidative phosphorylation, Disease and Programmed cell death in addition to Cell biology.

His Organelle study combines topics in areas such as Endoplasmic reticulum and Cytosol. His research in Calcium focuses on subjects like Inner mitochondrial membrane, which are connected to Biophysics, Antiporter and Mitochondrial matrix. His research integrates issues of Cellular homeostasis and Cellular respiration in his study of Calcium signaling.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca2+ Responses

    Rosario Rizzuto;Paolo Pinton;Paolo Pinton;Walter Carrington;Walter Carrington;Frederic S. Fay;Frederic S. Fay

  • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

    Diego De Stefani;Anna Raffaello;Enrico Teardo;Ildikò Szabò

  • Mitochondria as sensors and regulators of calcium signalling

    Rosario Rizzuto;Diego De Stefani;Anna Raffaello;Cristina Mammucari

  • Molecular and cellular physiology of intracellular calcium stores

    T. Pozzan;R. Rizzuto;P. Volpe;J. Meldolesi

  • Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria

    Rosario Rizzuto;Marisa Brini;Marta Murgia;Tullio Pozzan

  • Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

    György Szabadkai;Katiuscia Bianchi;Péter Várnai;Diego De Stefani

  • Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

    Rosario Rizzuto;Tullio Pozzan

  • Regulation of autophagy by cytoplasmic p53

    Ezgi Tasdemir;M. Chiara Maiuri;M. Chiara Maiuri;M. Chiara Maiuri;Lorenzo Galluzzi;Lorenzo Galluzzi;Lorenzo Galluzzi;Ilio Vitale;Ilio Vitale;Ilio Vitale

  • Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

    Marco Giorgio;Enrica Migliaccio;Francesca Orsini;Demis Paolucci

  • Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

    P Pinton;C Giorgi;C Giorgi;R Siviero;E Zecchini

  • Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

    Diego L. Medina;Simone Di Paola;Ivana Peluso;Andrea Armani

  • Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2

    Maria Høyer-Hansen;Lone Bastholm;Piotr Szyniarowski;Michelangelo Campanella

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin.

    Rosario Rizzuto;Alec W. M. Simpson;Alec W. M. Simpson;Marisa Brini;Tullio Pozzan

  • Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

    Laurence S. Jouaville;Paolo Pinton;Carlo Bastianutto;Guy A. Rutter

  • MAM: more than just a housekeeper

    Teruo Hayashi;Rosario Rizzuto;Gyorgy Hajnoczky;Tsung-Ping Su

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

    Verfaillie T;Rubio N;Rubio N;Garg Ad;Bultynck G

Frequent Co-Authors

Paolo Pinton
Paolo Pinton University of Ferrara
Tullio Pozzan
Tullio Pozzan University of Padua
Marisa Brini
Marisa Brini University of Padua
Gyorgy Szabadkai
Gyorgy Szabadkai University College London
Carlotta Giorgi
Carlotta Giorgi University of Ferrara
Guy A. Rutter
Guy A. Rutter Imperial College London
Mariusz R. Wieckowski
Mariusz R. Wieckowski Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
Eric A. Schon
Eric A. Schon Columbia University Medical Center
Ildikò Szabò
Ildikò Szabò University of Padua
Guido Kroemer
Guido Kroemer Université Paris Cité

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