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Francesco Di Virgilio

Francesco Di Virgilio

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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
115
Citations
49363
World Ranking
787
National Ranking
8

Medicine

D-Index
115
Citations
49341
World Ranking
4540
National Ranking
138

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award
  • 2016 - Member of Academia Europaea

Overview

Francesco Di Virgilio was affiliated with the University of Ferrara in Italy. Their research primarily focused on biochemistry, genetics, molecular biology, and medicine, with significant contributions in physiology, molecular biology, immunology, neurology, and surgery.

Their work extensively covered topics such as adenosine and purinergic signaling, neuroscience of respiration and sleep, adolescent and pediatric healthcare, vagus nerve stimulation research, COVID-19 impact on reproduction, extracellular vesicles in disease, and neurological complications and syndromes.

Among the recent publications were:

  • From purines to purinergic signalling: molecular functions and human diseases (2021, Signal Transduction and Targeted Therapy)
  • Apoptotic cell death in disease-Current understanding of the NCCD 2023 (2023, Cell Death and Differentiation)
  • Update of P2X receptor properties and their pharmacology: IUPHAR Review 30 (2020, British Journal of Pharmacology)
  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels (2021, British Journal of Pharmacology)
  • Extracellular ATP: A Feasible Target for Cancer Therapy (2020, Cells)

Their frequent co-authors included:

  • Simonetta Falzoni
  • Valentina Vultaggio-Poma
  • Elena Adinolfi
  • Anna Lisa Giuliani
  • Alba Clara Sarti

The scientist published repeatedly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Purinergic Signalling
  • British Journal of Pharmacology
  • Cell Death and Disease
  • IUPHAR/BPS Guide to Pharmacology CITE

Francesco Di Virgilio was recognized as a Member of Academia Europaea in 2016. Their research contributed to a broad understanding of biochemical signaling mechanisms and their roles in various human diseases and physiological processes throughout their career.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice.

    Mickaël Michaud;Mickaël Michaud;Mickaël Michaud;Isabelle Martins;Isabelle Martins;Isabelle Martins;Abdul Qader Sukkurwala;Abdul Qader Sukkurwala;Abdul Qader Sukkurwala;Sandy Adjemian;Sandy Adjemian;Sandy Adjemian

  • The P2X7 receptor: a key player in IL-1 processing and release.

    Davide Ferrari;Cinzia Pizzirani;Elena Adinolfi;Roberto M. Lemoli

  • Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation

    M.J.L. Bours;E.L.R. Swennen;F. Di Virgilio;B.N. Cronstein

  • The P2X7 Receptor in Infection and Inflammation

    Francesco Di Virgilio;Diego Dal Ben;Alba Clara Sarti;Anna Lisa Giuliani

  • Nucleotide receptors: an emerging family of regulatory molecules in blood cells.

    Francesco Di Virgilio;Paola Chiozzi;Davide Ferrari;Simonetta Falzoni

  • The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

    Paolo Pinton;Davide Ferrari;Elena Rapizzi;Francesco Di Virgilio

  • Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

    Patrizia Pellegatti;Lizzia Raffaghello;Giovanna Bianchi;Federica Piccardi

  • Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells.

    Marco Idzko;Hamida Hammad;Menno van Nimwegen;Mirjam Kool

  • Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.

    P Arslan;F Di Virgilio;M Beltrame;R Y Tsien

  • Calcium and apoptosis: facts and hypotheses.

    Rosario Rizzuto;Paolo Pinton;Davide Ferrari;Mounia Chami

  • Purinergic Modulation of Interleukin-1β Release from Microglial Cells Stimulated with Bacterial Endotoxin

    Davide Ferrari;Paola Chiozzi;Simonetta Falzoni;Stefania Hanau

  • Extracellular ATP and P2 purinergic signalling in the tumour microenvironment

    Francesco Di Virgilio;Alba Clara Sarti;Simonetta Falzoni;Elena De Marchi

  • Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

    Paolo Pinton;Davide Ferrari;Paulo Magalhães;Klaus Schulze-Osthoff

  • Liaisons dangereuses : P2X7 and the inflammasome

    Francesco Di Virgilio

  • Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

    Federico Pietrocola;Federico Pietrocola;Jonathan Pol;Erika Vacchelli;Erika Vacchelli;Shuan Rao

  • Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

    Konrad Wilhelm;Jayanthi Ganesan;Tobias Müller;Christoph Dürr

  • The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

    Francesco Di Virgilio

  • Inhibition of Fura-2 sequestration and secretion with organic anion transport blockers.

    F Di Virgilio;T.H Steinberg;S.C Silverstein

  • Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells.

    Juana M. Sanz;Francesco Di Virgilio

Frequent Co-Authors

Davide Ferrari
Davide Ferrari University of Ferrara
Simonetta Falzoni
Simonetta Falzoni University of Ferrara
Marco Idzko
Marco Idzko Medical University of Vienna
Johannes Norgauer
Johannes Norgauer Friedrich Schiller University Jena
Paolo Pinton
Paolo Pinton University of Ferrara
Rosario Rizzuto
Rosario Rizzuto University of Padua
Tullio Pozzan
Tullio Pozzan University of Padua
Romeo Romagnoli
Romeo Romagnoli University of Ferrara
Francesco Bertolini
Francesco Bertolini European Institute of Oncology
Giampiero Girolomoni
Giampiero Girolomoni University of Verona

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