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Medicine

D-Index
115
Citations
46849
World Ranking
4564
National Ranking
2479

Overview

Simon C. Robson is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research spans multiple interdisciplinary domains, primarily focused on medicine and biochemistry, genetics, and molecular biology.

The scientist's work includes significant publications in fields such as immunology, physiology, surgery, epidemiology, and molecular biology. Their research interests cover a range of key topics including adenosine and purinergic signaling, immune cell function and interaction, immune cells in cancer, neuroinflammation and neurodegeneration mechanisms, diabetes and associated disorders, COVID-19 clinical research studies, and liver diseases and immunity.

Simon C. Robson has contributed to numerous influential papers. Selected recent publications include:

  • Negative feedback control of neuronal activity by microglia, 2020, Nature
  • Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity, 2022, Nature Immunology
  • Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation, 2020, Cell Reports
  • Conversion of extracellular ATP into adenosine: a master switch in renal health and disease, 2020, Nature Reviews Nephrology
  • Control of Metastases via Myeloid CD39 and NK Cell Effector Function, 2020, Cancer Immunology Research

The scientist frequently collaborates with other researchers, including:

  • Maria Serena Longhi
  • Eva Csizmadia
  • Marta Vuerich
  • Harshal Nandurkar
  • Robina Matyal

Simon C. Robson's work has been published repeatedly in several leading scientific journals and venues. Most frequently, they have published in:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Circulation
  • International Journal of Molecular Sciences

The scientist's main fields of study include medicine, where they have contributed extensively, and biochemistry, genetics, and molecular biology. Their subfields of study emphasize immunology, physiology, surgery, epidemiology, and molecular biology.

Best Publications

  • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

    Silvia Deaglio;Karen M. Dwyer;Wenda Gao;David J Friedman

  • The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

    Simon Christopher Robson;Jean Sévigny;Herbert Zimmermann

  • Negative feedback control of neuronal activity by microglia

    Ana Badimon;Hayley J. Strasburger;Pinar Ayata;Xinhong Chen

  • The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.

    Bertrand Allard;Maria Serena Longhi;Simon C. Robson;John Stagg

  • Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience.

    Kenji Kuwaki;Yau Lin Tseng;Frank J.M.F. Dor;Akira Shimizu

  • Purinergic Signaling during Inflammation

    Holger K. Eltzschig;Michail V. Sitkovsky;Simon C. Robson

  • Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase

    Elzbieta Kaczmarek;Katarzyna Koziak;Jean Sévigny;Jonathan B. Siegel

  • Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

    Keiichi Enjyoji;Jean Sévigny;Yuan Lin;Paul S. Frenette

  • Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

    K. Sato;J. Balla;L. Otterbein;R. N. Smith

  • Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium Role of Ectonucleotidases and Adenosine A2B Receptors

    Holger K. Eltzschig;Juan C. Ibla;Glenn T. Furuta;Martin O. Leonard

  • Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

    Maisa C. Takenaka;Galina Gabriely;Veit Rothhammer;Ivan D. Mascanfroni

  • Delayed xenograft rejection

    Fritz H. Bach;Hans Winkler;Christiane Ferran;Wayne W. Hancock

  • CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

    Prakash K. Gupta;Prakash K. Gupta;Jernej Godec;Jernej Godec;David Wolski;Emily Adland

  • Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

    Ivan D Mascanfroni;Maisa C Takenaka;Ada Yeste;Bonny Patel

  • ATP Release From Activated Neutrophils Occurs via Connexin 43 and Modulates Adenosine-Dependent Endothelial Cell Function

    Holger K. Eltzschig;Tobias Eckle;Alice Mager;Natalie Küper

  • Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.

    Holger K. Eltzschig;Linda F. Thompson;Jorn Karhausen;Richard J. Cotta

  • CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness

    Norikatsu Mizumoto;Tadashi Kumamoto;Simon C. Robson;Jean Sévigny

  • IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

    Ivan D Mascanfroni;Ada Yeste;Silvio M Vieira;Evan J Burns

  • Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression.

    Fanny Chalmin;Grégoire Mignot;Mélanie Bruchard;Mélanie Bruchard;Angélique Chevriaux

  • Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8.

    F. Kukulski;S. A. Lévesque;É. G. Lavoie;J. Lecka

Frequent Co-Authors

Peter J. Cowan
Peter J. Cowan University of Melbourne
Jean Sévigny
Jean Sévigny Université Laval
Fritz H. Bach
Fritz H. Bach Harvard Medical School
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
David H. Sachs
David H. Sachs Columbia University
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania
Wolfgang G. Junger
Wolfgang G. Junger Beth Israel Deaconess Medical Center
Herbert Zimmermann
Herbert Zimmermann Goethe University Frankfurt
Leo E. Otterbein
Leo E. Otterbein Beth Israel Deaconess Medical Center
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School

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