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Medicine

D-Index
107
Citations
42078
World Ranking
6257
National Ranking
3339

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Holger K. Eltzschig is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research spans primarily across the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular attention to subfields such as Physiology, Cancer Research, Molecular Biology, Pulmonary and Respiratory Medicine, and Immunology.

The scientific work of Holger K. Eltzschig focuses on several main topics, including:

  • Adenosine and Purinergic Signaling
  • Cancer, Hypoxia, and Metabolism
  • MicroRNA in disease regulation
  • Respiratory Support and Mechanisms
  • Axon Guidance and Neuronal Signaling
  • Adipose Tissue and Metabolism
  • RNA Interference and Gene Delivery

Recent peer-reviewed publications authored by or involving Holger K. Eltzschig include:

  • "Circadian rhythm as a therapeutic target" (2021), published in Nature Reviews Drug Discovery
  • "Targeting hypoxia-inducible factors: therapeutic opportunities and challenges" (2023), published in Nature Reviews Drug Discovery
  • "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine" (2022), published in Nature
  • "Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity" (2020), published in Cell Metabolism
  • "Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis" (2021), published in Journal of Clinical Investigation

Frequent coauthors collaborating with Holger K. Eltzschig include:

  • Xiaoyi Yuan
  • Tingting Mills
  • Wei Ruan
  • Yafen Liang
  • Jennifer M. Bailey

Common publication venues for Holger K. Eltzschig's work consist of:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • JCI Insight
  • Frontiers in Immunology
  • The Journal of Immunology
  • Anesthesiology

Holger K. Eltzschig has received professional recognition as a member of the Association of American Physicians, an affiliation indicating engagement with esteemed peers in the medical research community.

Best Publications

  • Ischemia and reperfusion—from mechanism to translation

    Holger K Eltzschig;Tobias Eckle

  • Hypoxia and Inflammation

    Holger K Eltzschig;Peter Carmeliet

  • Adenosine receptors as drug targets — what are the challenges?

    Jiang-Fan Chen;Holger K. Eltzschig;Bertil B. Fredholm

  • Nucleotide signalling during inflammation

    Marco Idzko;Davide Ferrari;Holger K. Eltzschig

  • Purinergic Signaling during Inflammation

    Holger K. Eltzschig;Michail V. Sitkovsky;Simon C. Robson

  • Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

    Kristin Synnestvedt;Glenn T. Furuta;Katrina M. Comerford;Nancy Louis

  • Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia

    Linda F. Thompson;Holger K. Eltzschig;Juan C. Ibla;Juan C. Ibla;C. Justin Van De Wiele

  • Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

    Eric T. Clambey;Eóin N. McNamee;Joseph A. Westrich;Louise E. Glover

  • Vascular ischaemia and reperfusion injury.

    Holger K. Eltzschig;Charles D. Collard

  • Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium Role of Ectonucleotidases and Adenosine A2B Receptors

    Holger K. Eltzschig;Juan C. Ibla;Glenn T. Furuta;Martin O. Leonard

  • Hypoxia-Inducible Factor-1 Is Central to Cardioprotection A New Paradigm for Ischemic Preconditioning

    Tobias Eckle;David Köhler;Rainer Lehmann;Karim C. El Kasmi

  • Safety of Transesophageal Echocardiography

    Jan N. Hilberath;Daryl A. Oakes;Stanton K. Shernan;Bernard E. Bulwer

  • Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A2B Adenosine Receptors

    Tobias Eckle;Thomas Krahn;Almut Grenz;David Köhler

  • Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases

    Holger K. Eltzschig;Donna L. Bratton;Sean P. Colgan

  • Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.

    Peter Rosenberger;Jan M Schwab;Valbona Mirakaj;Eva Masekowsky

  • ATP Release From Activated Neutrophils Occurs via Connexin 43 and Modulates Adenosine-Dependent Endothelial Cell Function

    Holger K. Eltzschig;Tobias Eckle;Alice Mager;Natalie Küper

  • Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.

    Holger K. Eltzschig;Linda F. Thompson;Jorn Karhausen;Richard J. Cotta

  • Regional Anesthesia and Analgesia for Labor and Delivery

    Holger K Eltzschig;Ellice S Lieberman;William R Camann

  • HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia

    Holger K. Eltzschig;Parween Abdulla;Edgar Hoffman;Kathryn E. Hamilton

  • A2B adenosine receptor dampens hypoxia-induced vascular leak

    Tobias Eckle;Marion Faigle;Almut Grenz;Stefanie Laucher

Frequent Co-Authors

Michael R. Blackburn
Michael R. Blackburn The University of Texas Health Science Center at Houston
Sean P. Colgan
Sean P. Colgan University of Colorado Anschutz Medical Campus
Yang Xia
Yang Xia The University of Texas Health Science Center at Houston
Rodney E. Kellems
Rodney E. Kellems The University of Texas Health Science Center at Houston
Glenn T. Furuta
Glenn T. Furuta University of Colorado Denver
Simon C. Robson
Simon C. Robson Beth Israel Deaconess Medical Center
Linda F. Thompson
Linda F. Thompson Oklahoma Medical Research Foundation
Katya Ravid
Katya Ravid Boston University
Karin Klingel
Karin Klingel University of Tübingen
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver

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