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Medicine

D-Index
137
Citations
66813
World Ranking
1912
National Ranking
1086

Overview

Pal Pacher is a researcher affiliated with the National Institutes of Health in the United States. Their scientific contributions span multiple disciplines, with a primary focus on medicine and biochemistry, genetics, and molecular biology. Their work particularly emphasizes physiology, pharmacology, molecular biology, surgery, and epidemiology as notable subfields of study.

The research topics that Pal Pacher has extensively investigated include:

  • Cannabis and Cannabinoid Research
  • Alcohol Consumption and Health Effects
  • Adenosine and Purinergic Signaling
  • Liver Disease Diagnosis and Treatment
  • Pancreatic function and diabetes
  • Biochemical effects in animals
  • Lipoproteins and Cardiovascular Health

Among recent publications, the following papers represent significant contributions to their research portfolio:

  • Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223-enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis, 2020, Journal of Clinical Investigation
  • PARPs in lipid metabolism and related diseases, 2021, Progress in Lipid Research
  • Interplay of cardiovascular mediators, oxidative stress and inflammation in liver disease and its complications, 2020, Nature Reviews Cardiology
  • Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, 2020, Nature Chemical Biology
  • Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following liver injury, 2021, Journal of Clinical Investigation

Pal Pacher has collaborated frequently with several scientists, including:

  • György Haskó (23 coauthored publications)
  • János Pálóczi (14 coauthored publications)
  • Uwe Grether (13 coauthored publications)
  • Partha Mukhopadhyay (11 coauthored publications)
  • Mario van der Stelt (10 coauthored publications)

The main publication venues for Pal Pacher's research include:

  • GeroScience (8 publications)
  • American Journal Of Pathology (3 publications)
  • Journal of Clinical Investigation (2 publications)
  • Nature Communications (2 publications)
  • The FASEB Journal (2 publications)

In addition to journal articles, Pal Pacher has contributed to book publications. One notable work is the 2022 publication titled Therapeutic Potential of the Cannabinoid CB2 Receptor, published by Frontiers Media.

Best Publications

  • Nitric Oxide and Peroxynitrite in Health and Disease

    Pál Pacher;Joseph S. Beckman;Lucas Liaudet

  • The Endocannabinoid System as an Emerging Target of Pharmacotherapy

    Pál Pacher;Sándor Bátkai;George Kunos

  • Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol

    Pál Pacher;Alex Nivorozhkin;Csaba Szabó;Csaba Szabó

  • Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

    György Haskó;Joel Linden;Bruce Cronstein;Pál Pacher

  • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

    Douglas Osei-Hyiaman;Michael DePetrillo;Pál Pacher;Jie Liu

  • CD39 and CD73 in immunity and inflammation

    Luca Antonioli;Pál Pacher;E. Sylvester Vizi;E. Sylvester Vizi;György Haskó

  • NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

    Oleg V. Evgenov;Pál Pacher;Peter M. Schmidt;György Haskó

  • Activation of the peripheral endocannabinoid system in human obesity.

    Stefan Engeli;Jana Böhnke;Mareike Feldpausch;Kerstin Gorzelniak

  • Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats

    Pál Pacher;Takahiro Nagayama;Partha Mukhopadhyay;Sándor Bátkai

  • Immunity, inflammation and cancer: a leading role for adenosine

    Luca Antonioli;Corrado Blandizzi;Pál Pacher;György Haskó;György Haskó

  • Endocannabinoid signaling at the periphery: 50 years after THC

    Mauro Maccarrone;Itai Bab;Tamás Bíró;Guy A. Cabral

  • Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

    Nitin Agarwal;Pal Pacher;Irmgard Tegeder;Fumimasa Amaya

  • Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity

    Matthias Blüher;Stefan Engeli;Nora Klöting;Janin Berndt

  • Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

    Johannes-Peter Stasch;Pál Pacher;Oleg V. Evgenov

  • Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

    Mohanraj Rajesh;Partha Mukhopadhyay;Sándor Bátkai;Vivek Patel

  • Is lipid signaling through cannabinoid 2 receptors part of a protective system

    P. Pacher;R. Mechoulam

  • Evidence for novel cannabinoid receptors.

    Malcolm Begg;Pál Pacher;Sándor Bátkai;Douglas Osei-Hyiaman

  • Cardiovascular Side Effects of New Antidepressants and Antipsychotics: New Drugs, old Concerns?

    Pal Pacher;Pal Pacher;Valeria Kecskemeti

  • Drug-induced mitochondrial dysfunction and cardiotoxicity.

    Zoltán V Varga;Peter Ferdinandy;Lucas Liaudet;Pál Pacher

  • Basic Science for Clinicians Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

    Johannes-Peter Stasch;Pal Pacher;Oleg V. Evgenov

Frequent Co-Authors

György Haskó
György Haskó Columbia University
Csaba Szabó
Csaba Szabó University of Fribourg
Lucas Liaudet
Lucas Liaudet University of Lausanne
Sandor Batkai
Sandor Batkai Cardior Pharmaceuticals
George Kunos
George Kunos National Institutes of Health
Zoltan Ungvari
Zoltan Ungvari University of Oklahoma Health Sciences Center
Bin Gao
Bin Gao National Institutes of Health
Anna Csiszar
Anna Csiszar University of Oklahoma Health Sciences Center
László Virág
László Virág University of Debrecen
Ken Mackie
Ken Mackie Indiana University

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