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Medicine

D-Index
101
Citations
39647
World Ranking
7946
National Ranking
4132

Overview

George Kunos is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on medicine with significant contributions in biochemistry, genetics, and molecular biology. The scientist's work spans several subfields including pharmacology, molecular biology, pathology and forensic medicine, epidemiology, and physiology.

The research topics addressed by George Kunos cover:

  • Cannabis and Cannabinoid Research
  • Alcohol Consumption and Health Effects
  • Liver Disease Diagnosis and Treatment
  • Diet and Metabolism Studies
  • Pancreatic Function and Diabetes
  • Regulation of Appetite and Obesity
  • Neuroscience and Neuropharmacology Research

Frequent publication venues for George Kunos include:

  • Journal of Clinical Investigation
  • Hepatology
  • eGastroenterology
  • Nature Communications
  • Biomedicine & Pharmacotherapy

Among the recent scientific papers authored or co-authored by George Kunos are:

  • Myeloid-Cell-Specific IL-6 Signaling Promotes MicroRNA-223-Enriched Exosome Production to Attenuate NAFLD-Associated Fibrosis (2020, Hepatology)
  • Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223-enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis (2020, Journal of Clinical Investigation)
  • The therapeutic potential of second and third generation CB1R antagonists (2020, Pharmacology & Therapeutics)
  • Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models (2023, Journal of Clinical Investigation)
  • Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist (2021, ACS Pharmacology & Translational Science)

Frequent co-authors who have collaborated with George Kunos include:

  • Reşat Çınar
  • Malliga R. Iyer
  • Bin Gao
  • Dechun Feng
  • Grzegorz Godlewski

Best Publications

  • The Endocannabinoid System as an Emerging Target of Pharmacotherapy

    Pál Pacher;Sándor Bátkai;George Kunos

  • Leptin-regulated endocannabinoids are involved in maintaining food intake

    Vincenzo Di Marzo;Sravan K. Goparaju;Lei Wang;Lei Wang;Jie Liu;Jie Liu

  • International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

    Roger Guy Pertwee;A. C. Howlett;M. E. Abood;S. P. H. Alexander

  • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

    Douglas Osei-Hyiaman;Michael DePetrillo;Pál Pacher;Jie Liu

  • Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration

    Lisa Walter;Allyn Franklin;Anke Witting;Christian Wade

  • Endocannabinoid signaling at the periphery: 50 years after THC

    Mauro Maccarrone;Itai Bab;Tamás Bíró;Guy A. Cabral

  • Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.

    Zoltán Járai;Jens A. Wagner;Jens A. Wagner;Károly Varga;Kristy D. Lake

  • Presynaptic Specificity of Endocannabinoid Signaling in the Hippocampus

    Rachel I. Wilson;George Kunos;Roger A. Nicoll

  • Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

    Nitin Agarwal;Pal Pacher;Irmgard Tegeder;Fumimasa Amaya

  • A biosynthetic pathway for anandamide

    Jie Liu;Lei Wang;Judith Harvey-White;Douglas Osei-Hyiaman

  • Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

    Joseph Tam;V. Kiran Vemuri;Jie Liu;Sándor Bátkai

  • Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension

    Karoly Varga;Jens A. Wagner;D. Troy Bridgen;George Kunos

  • Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice.

    Douglas Osei-Hyiaman;Jie Liu;Liang Zhou;Grzegorz Godlewski

  • Evidence for novel cannabinoid receptors.

    Malcolm Begg;Pál Pacher;Sándor Bátkai;Douglas Osei-Hyiaman

  • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis

    Sándor Bátkai;Zoltán Járai;Jens A. Wagner;Sravan K. Goparaju

  • Modulating the endocannabinoid system in human health and disease--successes and failures.

    Pál Pacher;George Kunos

  • Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves.

    Edward J.N. Ishac;Liu Jiang;Kristy D. Lake;Karoly Varga

  • Functional CB1 cannabinoid receptors in human vascular endothelial cells.

    Jie Liu;Bin Gao;Faridoddin Mirshahi;Arun J. Sanyal

  • Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock.

    Jens A. Wagner;Kàroly Varga;Earl F. Ellis;Beverly A. Rzigalinski

  • Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.

    Tony Jourdan;Grzegorz Godlewski;Resat Cinar;Adeline Bertola

Frequent Co-Authors

Pal Pacher
Pal Pacher National Institutes of Health
Bin Gao
Bin Gao National Institutes of Health
Jie Liu
Jie Liu National Institutes of Health
Sandor Batkai
Sandor Batkai Cardior Pharmaceuticals
Ken Mackie
Ken Mackie Indiana University
Raj K. Razdan
Raj K. Razdan Organix (United States)
Alexandros Makriyannis
Alexandros Makriyannis Northeastern University
Adil Mardinoglu
Adil Mardinoglu Royal Institute of Technology
Billy R. Martin
Billy R. Martin Virginia Commonwealth University
Jerome E. Groopman
Jerome E. Groopman Beth Israel Deaconess Medical Center

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