D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 133 Citations 62,739 447 World Ranking 153 National Ranking 113

Research.com Recognitions

Awards & Achievements

2016 - Fellow of the American Academy of Arts and Sciences

2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His main research concerns Biochemistry, Fatty acid amide hydrolase, Anandamide, Endocannabinoid system and Cannabinoid receptor. Biochemistry is closely attributed to In vivo in his research. Benjamin F. Cravatt interconnects AM404, Hydrolase, Neocortex, Fatty acid and URB597 in the investigation of issues within Fatty acid amide hydrolase.

Benjamin F. Cravatt combines subjects such as Fatty acid amide, Cannabinoid, Endogeny, JZL184 and Pharmacology with his study of Anandamide. Benjamin F. Cravatt studies Endocannabinoid system, namely Monoacylglycerol lipase. His Proteome study combines topics from a wide range of disciplines, such as Amino acid, Molecular probe, Proteomics, Cysteine and Small molecule.

His most cited work include:

  • Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides (1738 citations)
  • Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase (1096 citations)
  • Quantitative reactivity profiling predicts functional cysteines in proteomes (884 citations)

What are the main themes of his work throughout his whole career to date?

Benjamin F. Cravatt mainly investigates Biochemistry, Fatty acid amide hydrolase, Endocannabinoid system, Anandamide and Enzyme. His study connects In vivo and Biochemistry. His research integrates issues of Oleamide, Amidase, Fatty acid, Stereochemistry and URB597 in his study of Fatty acid amide hydrolase.

His Endocannabinoid system research is multidisciplinary, relying on both Endocrinology, Pharmacology and Cannabinoid receptor. His research in Cannabinoid receptor intersects with topics in Cannabinoid and Neuroscience. The study incorporates disciplines such as Cysteine, Activity-based proteomics and Cell biology in addition to Proteome.

He most often published in these fields:

  • Biochemistry (40.10%)
  • Fatty acid amide hydrolase (27.03%)
  • Endocannabinoid system (24.49%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (12.69%)
  • Biochemistry (40.10%)
  • Endocannabinoid system (24.49%)

In recent papers he was focusing on the following fields of study:

Cell biology, Biochemistry, Endocannabinoid system, Monoacylglycerol lipase and Pharmacology are his primary areas of study. His Biochemistry study focuses mostly on Enzyme, Cysteine, Serine, In vitro and Metabolism. His work carried out in the field of Endocannabinoid system brings together such families of science as Fatty acid amide hydrolase, Anandamide, Cannabinoid receptor type 1 and Cannabinoid receptor.

Internal medicine covers Benjamin F. Cravatt research in Fatty acid amide hydrolase. His Cannabinoid receptor research includes elements of Cannabinoid and Neuroscience. The various areas that Benjamin F. Cravatt examines in his Pharmacology study include Proinflammatory cytokine, Neuroinflammation and Nicotine.

Between 2016 and 2021, his most popular works were:

  • How many human proteoforms are there (219 citations)
  • Ligand and Target Discovery by Fragment-Based Screening in Human Cells (165 citations)
  • Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 (155 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Benjamin F. Cravatt spends much of his time researching Cell biology, Biochemistry, Cysteine, Endocannabinoid system and Monoacylglycerol lipase. His Cell biology study combines topics in areas such as Receptor, Caenorhabditis elegans and Immune system. His Biochemistry study frequently links to related topics such as Biomarker.

His studies in Endocannabinoid system integrate themes in fields like Anandamide, Endocrinology, Fatty acid amide hydrolase and AM251. His Anandamide study is related to the wider topic of Cannabinoid receptor. His Monoacylglycerol lipase research is multidisciplinary, incorporating perspectives in Inflammation and Pharmacology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Benjamin F. Cravatt;Dan K. Giang;Stephen P. Mayfield;Dale L. Boger.
Nature (1996)

2288 Citations

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

Benjamin F. Cravatt;Kristin Demarest;Matthew P. Patricelli;Michael H. Bracey.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1750 Citations

Activity-based protein profiling: The serine hydrolases

Yongsheng Liu;Matthew P. Patricelli;Benjamin F. Cravatt.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1233 Citations

Activity-Based Protein Profiling in Vivo Using a Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

Anna E. Speers;Gregory C. Adam;Benjamin F. Cravatt.
Journal of the American Chemical Society (2003)

1208 Citations

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

Lindsey J. Macpherson;Adrienne E. Dubin;Michael J. Evans;Felix Marr;Felix Marr.
Nature (2007)

1111 Citations

Quantitative reactivity profiling predicts functional cysteines in proteomes

Eranthie Weerapana;Chu Wang;Gabriel M. Simon;Florian Richter.
Nature (2010)

1105 Citations

A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2-Arachidonoylglycerol

Jacqueline Lorayne Blankman;Gabriel M. Simon;Benjamin F. Cravatt.
Chemistry & Biology (2007)

1051 Citations

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

Benjamin F. Cravatt;Aaron T. Wright;John W. Kozarich.
Annual Review of Biochemistry (2008)

1044 Citations

Profiling Enzyme Activities In Vivo Using Click Chemistry Methods

Anna E Speers;Benjamin F Cravatt.
Chemistry & Biology (2004)

1013 Citations

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

Jonathan Z Long;Weiwei Li;Lamont Booker;James J Burston.
Nature Chemical Biology (2009)

891 Citations

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