World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
85
Citations
22777
World Ranking
1351
National Ranking
680

Biology and Biochemistry

D-Index
86
Citations
23013
World Ranking
3028
National Ranking
1539

Research.com Recognitions

  • 2005 - Fellow of Alfred P. Sloan Foundation
  • 1979 - Fellow of Alfred P. Sloan Foundation

Overview

Seth Blackshaw is affiliated with Johns Hopkins University School of Medicine in the United States. Their primary research areas include biochemistry, genetics, molecular biology, and neuroscience, with a significant focus on molecular biology and cellular and molecular neuroscience.

The scientist's work covers several main topics, including:

  • Retinal Development and Disorders
  • Single-cell and spatial transcriptomics
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Zebrafish Biomedical Research Applications
  • CRISPR and Genetic Engineering
  • Sleep and Wakefulness Research

Frequent coauthors collaborating with Seth Blackshaw include Dong Won Kim, Thanh Hoang, Jiang Qian, Clayton P. Santiago, and Isabella Palazzo.

Among notable recent publications are:

  • Gene regulatory networks controlling vertebrate retinal regeneration (2020) published in Science
  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development (2020) published in Developmental Cell
  • The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development (2020) published in Nature Communications
  • ASCOT identifies key regulators of neuronal subtype-specific splicing (2020) published in Nature Communications
  • Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina (2021) published in Cell Reports

Seth Blackshaw has published extensively in several journals and venues, frequently contributing to bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, eLife, SSRN Electronic Journal, and Glia.

The scientist has also contributed to book publications, including a title named Developmental Neuroendocrinology published in 2020 by Springer International Publishing.

Among awards, Seth Blackshaw has been named a Fellow of the Alfred P. Sloan Foundation twice, once in 1979 and again in 2005.

Best Publications

  • RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

    Christopher J. Donnelly;Ping-Wu Zhang;Jacqueline T. Pham;Aaron R. Haeusler

  • Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission.

    Herman Wolosker;Seth Blackshaw;Solomon H. Snyder

  • Genomic Analysis of Mouse Retinal Development

    Seth Blackshaw;Sanjiv Harpavat;Jeff Trimarchi;Li Cai

  • Single cell RNA-Seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification.

    Brian S. Clark;Genevieve L. Stein-O’Brien;Fion Shiau;Gabrielle H. Cannon

  • Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

    Daniel A Lee;Joseph L Bedont;Thomas Pak;Hong Wang

  • Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.

    Shaohui Hu;Zhi Xie;Akishi Onishi;Xueping Yu

  • Gene regulatory networks controlling vertebrate retinal regeneration

    Thanh Hoang;Jie Wang;Patrick Boyd;Fang Wang

  • The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.

    Guy Barry;J. A. Briggs;D. P. Vanichkina;E. M. Poth

  • A genomic atlas of mouse hypothalamic development

    Tomomi Shimogori;Daniel A Lee;Ana Miranda-Angulo;Yanqin Yang

  • Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

    Andrew A. Pieper;Daniel J. Brat;Daniel J. Brat;David K. Krug;Crystal C. Watkins

  • A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

    Yingfei Wang;Ran An;Ran An;George K. Umanah;Hyejin Park

  • Comprehensive Analysis of Photoreceptor Gene Expression and the Identification of Candidate Retinal Disease Genes

    Seth Blackshaw;Rebecca E. Fraioli;Takahisa Furukawa;Constance L. Cepko

  • Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain.

    Mikael J. L. Eliasson;Seth Blackshaw;Michael J. Schell;Solomon H. Snyder

  • Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis.

    Melanie M. Sohocki;Sara J. Bowne;Lori S. Sullivan;Seth Blackshaw

  • Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy.

    Crystal C. Watkins;Akira Sawa;Samie Jaffrey;Seth Blackshaw

  • Encephalopsin: A Novel Mammalian Extraretinal Opsin Discretely Localized in the Brain

    Seth Blackshaw;Solomon H. Snyder

  • Cain, a novel physiologic protein inhibitor of calcineurin.

    Michael M. Lai;Patrick E. Burnett;Herman Wolosker;Seth Blackshaw

  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development

    Yufeng Lu;Fion Shiau;Wenyang Yi;Suying Lu

  • Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa

    Sara J. Bowne;Lori S. Sullivan;Susan H. Blanton;Constance L. Cepko

  • The long noncoding RNA RNCR2 directs mouse retinal cell specification

    Nicole A Rapicavoli;Erin M Poth;Seth Blackshaw

  • Interaction of RAFT1 with Gephyrin Required for Rapamycin-Sensitive Signaling

    David M. Sabatini;Roxanne K. Barrow;Seth Blackshaw;Patrick E. Burnett

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Jiang Qian
Jiang Qian Johns Hopkins University School of Medicine
Heng Zhu
Heng Zhu Johns Hopkins University School of Medicine
Constance L. Cepko
Constance L. Cepko Harvard University
Samer Hattar
Samer Hattar National Institutes of Health
Randy J. Nelson
Randy J. Nelson West Virginia University
G. William Wong
G. William Wong Johns Hopkins University School of Medicine
Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Stephen P. Daiger
Stephen P. Daiger The University of Texas Health Science Center at Houston
Jef D. Boeke
Jef D. Boeke New York University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students considering a future in neuroscience, online education offers flexible options tailored to diverse needs and goals. Many accredited institutions now provide accelerated bachelor degree programs that let you complete coursework and enter the workforce faster. These programs can be ideal if you want to move quickly into research roles or further graduate studies.

Choosing the right major is also crucial for career success. Resources like what bachelors degree should I get and most profitable majors offer insights into which programs can lead to higher-paying positions in science, healthcare, and beyond. Neuroscience often overlaps with these areas, opening doors to both clinical and research-based careers.

Affordability is a key concern for many students. Fortunately, there are fafsa-approved online certificate programs that provide recognized credentials at a lower cost. Exploring these pathways can help you manage expenses while pursuing meaningful roles in neuroscience and related fields.

Best Scientists Citing Seth Blackshaw

Trending Scientists

Recently Published Articles