1997 - Sheila Essey Award for ALS Research, American Academy of Neurology
Member of the Association of American Physicians
His main research concerns Amyotrophic lateral sclerosis, Neuroscience, Glutamate receptor, Motor neuron and Cell biology. The study incorporates disciplines such as Degenerative disease, Neurodegeneration and Spinal cord in addition to Amyotrophic lateral sclerosis. His work deals with themes such as Disease and Stem cell, which intersect with Neuroscience.
Jeffrey D. Rothstein combines subjects such as NMDA receptor, Pharmacology and Excitatory postsynaptic potential with his study of Glutamate receptor. His Motor neuron research includes themes of Neurotrophic factors, Neuron, Transplantation and Nervous system. His Cell biology research is multidisciplinary, relying on both Transporter, Neurite, Glutamate Plasma Membrane Transport Proteins, Biochemistry and Glutamate aspartate transporter.
Jeffrey D. Rothstein spends much of his time researching Neuroscience, Amyotrophic lateral sclerosis, Glutamate receptor, Cell biology and Motor neuron. The concepts of his Neuroscience study are interwoven with issues in AMPA receptor and Disease. His Amyotrophic lateral sclerosis study combines topics in areas such as Motor cortex, Neurodegeneration and Spinal cord.
His research in Glutamate receptor intersects with topics in Endocrinology and Transporter. His Cell biology study also includes fields such as
His primary areas of investigation include Cell biology, Amyotrophic lateral sclerosis, C9orf72, Neuroscience and Neurodegeneration. Jeffrey D. Rothstein has included themes like Monocarboxylate transporter 1, Nucleocytoplasmic Transport, Nuclear transport and Microphthalmia-associated transcription factor in his Cell biology study. His Amyotrophic lateral sclerosis study integrates concerns from other disciplines, such as Molecular biology and Immunology.
His C9orf72 research includes elements of RNA, Genetics, Cancer research and Mutation. His work carried out in the field of Neuroscience brings together such families of science as Disease and Induced pluripotent stem cell. Jeffrey D. Rothstein interconnects Autophagy, Transgene, Ran, HEK 293 cells and Stress granule in the investigation of issues within Neurodegeneration.
His primary areas of study are Cell biology, C9orf72, Neurodegeneration, Neuroscience and Amyotrophic lateral sclerosis. His studies deal with areas such as Myelin and Adenosine triphosphate as well as Cell biology. His C9orf72 research integrates issues from RNA, Genetics and Mutation.
The study incorporates disciplines such as Stress granule and Nucleocytoplasmic Transport in addition to Neurodegeneration. The study of Neuroscience is intertwined with the study of Response to injury in a number of ways. Jeffrey D. Rothstein usually deals with Amyotrophic lateral sclerosis and limits it to topics linked to Motor neuron and Denervation and Neuroglia.
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
Alan E. Renton;Elisa Majounie;Adrian James Waite;Javier Simón-Sánchez;Javier Simón-Sánchez.
Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate
Jeffrey D Rothstein;Margaret Dykes-Hoberg;Carlos A Pardo;Lynn A Bristol.
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
Oleg Butovsky;Mark P Jedrychowski;Craig S Moore;Ron Cialic.
Nature Neuroscience (2014)
Localization of neuronal and glial glutamate transporters
Jeffrey D. Rothstein;Lee Martin;Allan I. Levey;Margaret Dykes-Hoberg.
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
Jeffrey D. Rothstein;Marleen Van Kammen;Allan I. Levey;Lee J. Martin.
Annals of Neurology (1995)
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Jeffrey D. Rothstein;Sarjubhai Patel;Melissa R. Regan;Christine Haenggeli.
From charcot to lou gehrig: deciphering selective motor neuron death in als
Don W. Cleveland;Jeffrey D. Rothstein.
Nature Reviews Neuroscience (2001)
ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
L. I. Bruijn;M. W. Becher;M. K. Lee;K. L. Anderson.
Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis
Jeffrey D. Rothstein;Lee J. Martin;Ralph W. Kuncl.
The New England Journal of Medicine (1992)
Oligodendroglia metabolically support axons and contribute to neurodegeneration
Youngjin Lee;Brett M. Morrison;Yun Li;Sylvain Lengacher.
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