What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His main research concerns Amyotrophic lateral sclerosis, Neuroscience, Glutamate receptor, Motor neuron and Cell biology.
The study incorporates disciplines such as Degenerative disease, Neurodegeneration and Spinal cord in addition to Amyotrophic lateral sclerosis.
His work deals with themes such as Disease and Stem cell, which intersect with Neuroscience.
Jeffrey D. Rothstein combines subjects such as NMDA receptor, Pharmacology and Excitatory postsynaptic potential with his study of Glutamate receptor.
His Motor neuron research includes themes of Neurotrophic factors, Neuron, Transplantation and Nervous system.
His Cell biology research is multidisciplinary, relying on both Transporter, Neurite, Glutamate Plasma Membrane Transport Proteins, Biochemistry and Glutamate aspartate transporter.
His most cited work include:
- A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD (2859 citations)
- Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate (2133 citations)
- Localization of neuronal and glial glutamate transporters (1481 citations)
What are the main themes of his work throughout his whole career to date?
Jeffrey D. Rothstein spends much of his time researching Neuroscience, Amyotrophic lateral sclerosis, Glutamate receptor, Cell biology and Motor neuron.
The concepts of his Neuroscience study are interwoven with issues in AMPA receptor and Disease.
His Amyotrophic lateral sclerosis study combines topics in areas such as Motor cortex, Neurodegeneration and Spinal cord.
His research in Glutamate receptor intersects with topics in Endocrinology and Transporter.
His Cell biology study also includes fields such as
- Glutamate aspartate transporter which connect with Excitatory Amino Acid Transporter 3 and Metabotropic glutamate receptor 6,
- C9orf72 which intersects with area such as C9orf72 Protein and Genetics.
His research integrates issues of Neurotrophic factors and Neuroprotection in his study of Motor neuron.
He most often published in these fields:
- Neuroscience (36.19%)
- Amyotrophic lateral sclerosis (33.70%)
- Glutamate receptor (29.28%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (26.52%)
- Amyotrophic lateral sclerosis (33.70%)
- C9orf72 (9.12%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Amyotrophic lateral sclerosis, C9orf72, Neuroscience and Neurodegeneration.
Jeffrey D. Rothstein has included themes like Monocarboxylate transporter 1, Nucleocytoplasmic Transport, Nuclear transport and Microphthalmia-associated transcription factor in his Cell biology study.
His Amyotrophic lateral sclerosis study integrates concerns from other disciplines, such as Molecular biology and Immunology.
His C9orf72 research includes elements of RNA, Genetics, Cancer research and Mutation.
His work carried out in the field of Neuroscience brings together such families of science as Disease and Induced pluripotent stem cell.
Jeffrey D. Rothstein interconnects Autophagy, Transgene, Ran, HEK 293 cells and Stress granule in the investigation of issues within Neurodegeneration.
Between 2014 and 2021, his most popular works were:
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport (559 citations)
- Human endogenous retrovirus-K contributes to motor neuron disease (221 citations)
- C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins (166 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
His primary areas of study are Cell biology, C9orf72, Neurodegeneration, Neuroscience and Amyotrophic lateral sclerosis.
His studies deal with areas such as Myelin and Adenosine triphosphate as well as Cell biology.
His C9orf72 research integrates issues from RNA, Genetics and Mutation.
The study incorporates disciplines such as Stress granule and Nucleocytoplasmic Transport in addition to Neurodegeneration.
The study of Neuroscience is intertwined with the study of Response to injury in a number of ways.
Jeffrey D. Rothstein usually deals with Amyotrophic lateral sclerosis and limits it to topics linked to Motor neuron and Denervation and Neuroglia.
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