World's Best Scientists 2026 revealed!

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Immunology

D-Index
67
Citations
15024
World Ranking
2680
National Ranking
109

Genetics

D-Index
65
Citations
12452
World Ranking
2719
National Ranking
108

Overview

Nobuhisa Mizuki is affiliated with Yokohama City University in Japan and has an extensive research portfolio primarily within the field of medicine, with a focus on ophthalmology. Their work encompasses a broad range of subfields including radiology, nuclear medicine, epidemiology, public health, environmental and occupational health, and rheumatology.

The scientist's research topics cover several critical areas related to ocular health, including ocular diseases and Behçet's syndrome, corneal surgery and disorders, glaucoma and retinal disorders, ocular surface and contact lens applications, intraocular surgery and lenses, retinal and optic conditions, and treatments for nasolacrimal duct obstruction.

Mizuki has contributed to numerous studies published across various journals. Notable recent papers include:

  • New vaccine production platforms used in developing SARS-CoV-2 vaccine candidates, 2020, Vaccine
  • Evidence-based diagnosis and clinical practice guidelines for intestinal Behçet's disease 2020 edited by Intractable Diseases, the Health and Labour Sciences Research Grants, 2020, Journal of Gastroenterology
  • Changes in the proportion of clinical clusters contribute to the phenotypic evolution of Behçet's disease in Japan, 2021, Arthritis Research & Therapy
  • Pathogenesis of Non-Infectious Uveitis Elucidated by Recent Genetic Findings, 2021, Frontiers in Immunology
  • Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia, 2021, JAMA Ophthalmology

Frequent coauthors working alongside Mizuki include Masaki Takeuchi, Akira Meguro, Takeshi Teshigawara, Jutaro Nakamura, and Yuki Mizuki. Collaboration with these researchers has been consistent, reflecting shared scientific interests.

The scientist's research has been frequently published in venues such as:

  • Research Square (Research Square)
  • Scientific Reports
  • Clinical Ophthalmology
  • Ophthalmology and Therapy
  • Japanese Journal of Ophthalmology

Best Publications

  • Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

    Yohei Kirino;George Bertsias;George Bertsias;Yoshiaki Ishigatsubo;Nobuhisa Mizuki

  • Genome-wide association studies identify IL23R - IL12RB2 and IL10 as Behçet's disease susceptibility loci

    Nobuhisa Mizuki;Akira Meguro;Masao Ota;Shigeaki Ohno

  • Triplet repeat polymorphism in the transmembrane region of the MICA gene: A strong association of six GCT repetitions with Behçet disease

    Nobuhisa Mizuki;Masao Ota;Minoru Kimura;Shigeaki Ohno

  • Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth

    Romulo J C Albuquerque;Takahiko Hayashi;Won Gil Cho;Mark E Kleinman

  • Effects of Astaxanthin on Lipopolysaccharide-Induced Inflammation In Vitro and In Vivo

    Kazuhiro Ohgami;Kenji Shiratori;Satoshi Kotake;Tomomi Nishida

  • High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population.

    Yoshiki Itoh;Nobuhisa Mizuki;Tsuyako Shimada;Fumihiro Azuma

  • HLA class II molecules and autoimmune hepatitis susceptibility in Japanese patients.

    Takeshi Seki;Takeshi Seki;Takeshi Seki;Masao Ota;Masao Ota;Masao Ota;Seiichi Furuta;Seiichi Furuta;Seiichi Furuta;Hirohumi Fukushima;Hirohumi Fukushima;Hirohumi Fukushima

  • Modified PCR‐RFLP method for HLA‐DPB1 and ‐DQA1 genotyping

    Ota M;Seki T;Nomura N;Sugimura K

  • Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain-related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian

    M. Ota;Y. Katsuyama;N. Mizuki;H. Ando

  • Allelic repertoire of the human MHC class I MICA gene.

    Nassima Fodil;Laurent Laloux;Valérie Wanner;Philippe Pellet

  • Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

    Ching-Yu Cheng;Ching-Yu Cheng;Maria Schache;M. Kamran Ikram;M. Kamran Ikram;M. Kamran Ikram;Terri L. Young;Terri L. Young

  • Genetics of Behçet disease inside and outside the MHC

    Akira Meguro;Hidetoshi Inoko;Masao Ota;Yoshihiko Katsuyama

  • NUCLEOTIDE SEQUENCE OF THE HUMAN MHC CLASS I MICA GENE

    Seiamak Bahram;Nobuhisa Mizuki;Hidetoshi Inoko;Thomas Spies

  • Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility.

    Masaki Takeuchi;Masaki Takeuchi;Nobuhisa Mizuki;Akira Meguro;Michael J Ombrello

  • Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease

    Yohei Kirino;Qing Zhou;Yoshiaki Ishigatsubo;Nobuhisa Mizuki

  • Immunology and functional genomics of Behçet's disease.

    M. Zierhut;N. Mizuki;S. Ohno;H. Inoko

  • Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

    Qiao Fan;Qiao Fan;Virginie J M Verhoeven;Robert Wojciechowski;Robert Wojciechowski;Veluchamy A. Barathi

  • Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.

    Akira Meguro;Hidetoshi Inoko;Masao Ota

  • Nucleotide sequence analysis of the HLA class I region spanning the 237-kb segment around the HLA-B and -C genes.

    Nobuhisa Mizuki;Nobuhisa Mizuki;Hitoshi Ando;Minoru Kimura;Shigeaki Ohno

  • A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region.

    Masao Ota;Yoshihiko Katsuyama;Akinori Kimura;Kuniyoshi Tsuchiya

  • Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behçet's disease

    Yun Jong Lee;Yukihiro Horie;Graham R Wallace;Yong Seok Choi

Frequent Co-Authors

Hidetoshi Inoko
Hidetoshi Inoko Tokai University
Shigeaki Ohno
Shigeaki Ohno Hokkaido University
Masao Ota
Masao Ota Shinshu University
Yoshihiko Katsuyama
Yoshihiko Katsuyama Shinshu University
Seiamak Bahram
Seiamak Bahram University of Strasbourg
Elaine F. Remmers
Elaine F. Remmers National Institutes of Health
Ahmet Gül
Ahmet Gül Istanbul University
Teruo Nishida
Teruo Nishida Yamaguchi University
Daniel L. Kastner
Daniel L. Kastner National Institutes of Health
Chiea Chuen Khor
Chiea Chuen Khor Agency for Science, Technology and Research

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