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Overview

Seiamak Bahram is a researcher affiliated with the University of Strasbourg in France. Their scientific work primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these domains, they have focused on specialized subfields including Immunology, Molecular Biology, Genetics, Hematology, and Epidemiology.

Their research covers a range of topics, notably:

  • Immune Cell Function and Interaction
  • Systemic Lupus Erythematosus Research
  • Autoimmune and Inflammatory Disorders Research
  • Platelet Disorders and Treatments
  • COVID-19 Clinical Research Studies
  • Immunodeficiency and Autoimmune Disorders
  • Genetic and Kidney Cyst Diseases

Seiamak Bahram has contributed to numerous scientific publications throughout their career. Some recent examples include:

  • Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort, 2021, published in Science Translational Medicine
  • NCKAP1Ldefects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation, 2020, The Journal of Experimental Medicine
  • Refining "Long-COVID" by a Prospective Multimodal Evaluation of Patients with Long-Term Symptoms Attributed to SARS-CoV-2 Infection, 2021, Infectious Diseases and Therapy
  • JAK-STAT Targeting Offers Novel Therapeutic Opportunities in Sepsis, 2020, Trends in Molecular Medicine
  • Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria, 2023, Science Immunology

Their frequent co-authors include the following collaborators:

  • Raphaël Carapito
  • Anne Molitor
  • Angélique Pichot
  • Nicodème Paul
  • Jean Sibilia

Seiamak Bahram often publishes in venues such as:

  • Genes and Immunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Revue du Rhumatisme
  • Cell

Best Publications

  • Complete sequence and gene map of a human major histocompatibility complex

    S Beck;D Geraghty;H Inoko;L Rowen

  • Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

    Veronika Groh;Seiamak Bahram;Stefan Bauer;Andrew Herman

  • Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

    Emmanuel Treiner;Livine Duban;Seiamak Bahram;Mirjana Radosavljevic

  • A second lineage of mammalian major histocompatibility complex class I genes

    Seiamak Bahram;Maureen Bresnahan;Daniel E. Geraghty;Thomas Spies

  • A Direct Role for NKG2D/MICA Interaction in Villous Atrophy during Celiac Disease

    Sophie Hüe;Jean Jacques Mention;Renato C. Monteiro;Shao Ling Zhang

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Genome-wide association studies identify IL23R - IL12RB2 and IL10 as Behçet's disease susceptibility loci

    Nobuhisa Mizuki;Akira Meguro;Masao Ota;Shigeaki Ohno

  • Triplet repeat polymorphism in the transmembrane region of the MICA gene: A strong association of six GCT repetitions with Behçet disease

    Nobuhisa Mizuki;Masao Ota;Minoru Kimura;Shigeaki Ohno

  • Effect of hepcidin on intestinal iron absorption in mice.

    Abas H. Laftah;Bala Ramesh;Robert J. Simpson;Nita Solanky

  • Allelic variants of the human putative peptide transporter involved in antigen processing.

    Marco Colonna;Maureen Bresnahan;Seiamak Bahram;Jack L. Strominger

  • MIC genes: from genetics to biology.

    Seiamak Bahram

  • The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice.

    Philippe Georgel;Mirjana Radosavljevic;Cécile Macquin;Seiamak Bahram

  • Association Analysis Using Refined Microsatellite Markers Localizes a Susceptibility Locus for Psoriasis Vulgaris Within a 111 kb Segment Telomeric to the HLA-C Gene

    Akira Oka;Gen Tamiya;Maiko Tomizawa;Masao Ota

  • Genomics, Isoforms, Expression, and Phylogeny of the MHC Class I-Related MR1 Gene

    Patricia Riegert;Valérie Wanner;Seiamak Bahram

  • Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region.

    Seiamak Bahram;Daniele Arnold;Maureen Bresnahan;Jack L. Strominger

  • Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain-related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian

    M. Ota;Y. Katsuyama;N. Mizuki;H. Ando

  • Experimental hemochromatosis due to MHC class I HFE deficiency: Immune status and iron metabolism

    Seiamak Bahram;Susan Gilfillan;Lukas C. Kühn;Rémy Moret

  • Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region.

    Takashi Shiina;Gen Tamiya;Akira Oka;Nobusada Takishima

  • A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

    Mirjana Radosavljevic;Benoı̂t Cuillerier;Michael J. Wilson;Oliver Clément

  • Allelic repertoire of the human MHC class I MICA gene.

    Nassima Fodil;Laurent Laloux;Valérie Wanner;Philippe Pellet

Frequent Co-Authors

Hidetoshi Inoko
Hidetoshi Inoko Tokai University
Philippe Georgel
Philippe Georgel University of Strasbourg
Masao Ota
Masao Ota Shinshu University
Jean Sibilia
Jean Sibilia University of Strasbourg
Nobuhisa Mizuki
Nobuhisa Mizuki Yokohama City University
Yoshihiko Katsuyama
Yoshihiko Katsuyama Shinshu University
Shigeaki Ohno
Shigeaki Ohno Hokkaido University
Dominique Charron
Dominique Charron Grenoble Alpes University
Samira Fafi-Kremer
Samira Fafi-Kremer University of Strasbourg
Jerzy K. Kulski
Jerzy K. Kulski University of Western Australia

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