World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
32415
World Ranking
12245
National Ranking
940

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Irina Petrache is affiliated with the University of Cambridge in the United Kingdom and has contributed extensively to the field of medicine, with a focus on pulmonary and respiratory medicine. Their research spans multiple subfields including molecular biology, physiology, epidemiology, and immunology, reflecting a comprehensive approach to respiratory health and disease mechanisms.

The main topics addressed in their work include chronic obstructive pulmonary disease (COPD) research, pulmonary hypertension research and treatments, neonatal respiratory health research, sphingolipid metabolism and signaling, respiratory support and mechanisms, asthma and respiratory diseases, and health and medical research impacts.

Irina Petrache has published in several notable scientific venues. Frequent publication venues include:

  • American Journal of Respiratory and Critical Care Medicine
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • American Journal of Respiratory Cell and Molecular Biology
  • Annals of the American Thoracic Society
  • Metabolites

They have collaborated with various researchers in their field, with frequent co-authors including:

  • Kelly S. Schweitzer
  • Karina A. Serban
  • Evgeny Berdyshev
  • Hong Wei Chu
  • Jesse Roman

Recent publications by Irina Petrache focus on respiratory health and related metabolic dysfunctions. Selected papers include:

  • Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC), 2022, Metabolites
  • Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells, 2021, European Respiratory Journal
  • Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells, 2020, Journal of Inflammation Research
  • Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension, 2020, Scientific Reports
  • Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation, 2020, Molecular Metabolism

Irina Petrache has been recognized as a Member of the Association of American Physicians. Their body of work primarily contributes to understanding respiratory diseases, metabolic signaling, and pulmonary vascular remodeling.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

    Tirumalai Rangasamy;Chung Y. Cho;Rajesh K. Thimmulappa;Lijie Zhen

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Pathogenesis of chronic obstructive pulmonary disease

    Rubin M. Tuder;Irina Petrache

  • Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.

    Irina Petrache;Viswanathan Natarajan;Lijie Zhen;Terry R Medler

  • Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts

    Irina Petrache;Leo E. Otterbein;Leo E. Otterbein;Jawed Alam;Gordon W. Wiegand

  • The role of the microtubules in tumor necrosis factor-α-induced endothelial cell permeability

    Irina Petrache;Anna Birukova;Sarah I. Ramirez;Joe G. N. Garcia

  • α-1 Antitrypsin Inhibits Caspase-3 Activity, Preventing Lung Endothelial Cell Apoptosis

    Irina Petrache;Iwona Fijalkowska;Terry R. Medler;Jarrett Skirball

  • Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures

    Kelly S Schweitzer;Steven X Chen;Sarah Law;Mary J Van Demark

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Differential effect of MLC kinase in TNF-α-induced endothelial cell apoptosis and barrier dysfunction

    Irina Petrache;Alexander Dmitriyevich Verin;Michael T. Crow;Anna Birukova

  • Apoptosis and emphysema: the missing link.

    Rubin M. Tuder;Irina Petrache;Jack A. Elias;Norbert F. Voelkel

  • Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke–induced pulmonary injury and emphysema

    Toshinori Yoshida;Igor Mett;Anil K Bhunia;Joel Bowman

  • Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective

    Rubin M. Tuder;Toshinori Yoshida;Wadih Arap;Renata Pasqualini

  • A Novel Antiapoptotic Role for α1-Antitrypsin in the Prevention of Pulmonary Emphysema

    Irina Petrache;Iwona Fijalkowska;Lijie Zhen;Terry R. Medler

  • Adipose Stem Cell Treatment in Mice Attenuates Lung and Systemic Injury Induced by Cigarette Smoking

    Kelly S. Schweitzer;Brian H. Johnstone;Jana Garrison;Natalia I. Rush

  • 17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

    Tim Lahm;Marjorie Albrecht;Amanda J. Fisher;Mona Selej

  • Progress In Solving The Sex Hormone Paradox In Pulmonary Hypertension

    Tim Lahm;Rubin M. Tuder;Irina Petrache

  • Pathogenesis of chronic obstructive pulmonary disease (Journal of Clinical Investigation (2012) 122, 11 (4300) DOI: 10.1172/JCI66725)

    Rubin M. Tuder;Irina Petrache

Frequent Co-Authors

Rubin M. Tuder
Rubin M. Tuder University of Colorado Denver
Matthias Clauss
Matthias Clauss Indiana University
Russell P. Bowler
Russell P. Bowler Cleveland Clinic
Augustine M. K. Choi
Augustine M. K. Choi Cornell University
Patty J. Lee
Patty J. Lee Duke University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Robert Bittman
Robert Bittman City University of New York
Sergio Lavandero
Sergio Lavandero University of Chile
Joe G.N. Garcia
Joe G.N. Garcia University of Arizona
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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