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Biology and Biochemistry

D-Index
90
Citations
34924
World Ranking
2407
National Ranking
1277

Overview

Shyam Biswal is affiliated with Johns Hopkins University in the United States and has an extensive research portfolio primarily in medicine and environmental science. Their work spans several subfields, including health, toxicology and mutagenesis, molecular biology, pulmonary and respiratory medicine, physiology, and public health, environmental and occupational health.

Their research covers multiple main topics related to environmental and respiratory health, with a focus on air quality and health impacts, climate change and health impacts, genomics, phytochemicals, and oxidative stress, allergic rhinitis and sensitization, inhalation and respiratory drug delivery, indoor air quality and microbial exposure, and neonatal respiratory health research.

Some of Shyam Biswal's recent papers include:

  • "Environmental determinants of cardiovascular disease: lessons learned from air pollution," 2020, Nature Reviews Cardiology
  • "NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes," 2020, Clinical Cancer Research
  • "Association Between E-Cigarette Use and Chronic Obstructive Pulmonary Disease by Smoking Status: Behavioral Risk Factor Surveillance System 2016 and 2017," 2020, American Journal of Preventive Medicine
  • "Metabolic effects of air pollution exposure and reversibility," 2020, Journal of Clinical Investigation
  • "Prenatal Environmental Metal Exposure and Preterm Birth: A Scoping Review," 2021, International Journal of Environmental Research and Public Health

Frequent coauthors in their research include Murugappan Ramanathan, Zhenyu Zhang, Bongsoo Park, Sanjay Rajagopalan, and Nyall R. London.

Shyam Biswal has published widely in journals such as bioRxiv (Cold Spring Harbor Laboratory), Indian Journal of Animal Research, International Forum of Allergy & Rhinology, Scientific Reports, and International Journal of Infectious Diseases.

Best Publications

  • Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway

    Thomas W. Kensler;Nobunao Wakabayashi;Shyam Biswal

  • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.

    Rajesh K. Thimmulappa;Kim H. Mai;Sorachai Srisuma;Thomas W. Kensler

  • Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.

    Anju Singh;Vikas Misra;Rajesh K Thimmulappa;Hannah Lee

  • Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

    Rajesh K. Thimmulappa;Hannah Lee;Tirumalai Rangasamy;Sekhar P. Reddy

  • Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

    Tirumalai Rangasamy;Chung Y. Cho;Rajesh K. Thimmulappa;Lijie Zhen

  • Multiple-laboratory comparison of microarray platforms

    Rafael A Irizarry;Daniel Warren;Forrest Spencer;Irene F Kim

  • Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

    Deepti Malhotra;Elodie Portales-Casamar;Anju Singh;Siddhartha Srivastava

  • Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice.

    Tirumalai Rangasamy;Jia Guo;Wayne A. Mitzner;Jessica Roman

  • The Molecular Effects of Acrolein

    James P. Kehrer;Shyam S. Biswal

  • Environmental determinants of cardiovascular disease: lessons learned from air pollution.

    Sadeer G. Al-Kindi;Robert D. Brook;Shyam Biswal;Sanjay Rajagopalan

  • Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

    C.J. Harvey;R.K. Thimmulappa;A. Singh;D.J. Blake

  • Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model

    Thomas E. Sussan;Sachin Gajghate;Rajesh K. Thimmulappa;Jinfang Ma

  • Nrf2 and Keap1 Abnormalities in Non–Small Cell Lung Carcinoma and Association with Clinicopathologic Features

    Luisa M. Solis;Carmen Behrens;Wenli Dong;Milind Suraokar

  • Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

    Anju Singh;Sreedhar Venkannagari;Kyu H. Oh;Ya Qin Zhang

  • Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

    Deepti Malhotra;Rajesh Thimmulappa;Ana Navas-Acien;Andrew Sandford

  • RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.

    Anju Singh;Swetlana Boldin-Adamsky;Rajesh K. Thimmulappa;Srikanta K. Rath

  • Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

    Ping Zhang;Anju Singh;Srinivasan Yegnasubramanian;David Esopi

  • Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

    Rajesh K. Thimmulappa;Catherine Scollick;Kassim Traore;Melinda Yates

  • Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.

    Thomas E. Sussan;Tirumalai Rangasamy;Tirumalai Rangasamy;David J. Blake;Deepti Malhotra

  • NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.

    Soona Shin;Nobunao Wakabayashi;Vikas Misra;Shyam Biswal

Frequent Co-Authors

Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Thomas W. Kensler
Thomas W. Kensler Johns Hopkins University
Rubin M. Tuder
Rubin M. Tuder University of Colorado Denver
Robert A. Wise
Robert A. Wise Johns Hopkins University School of Medicine
Sekhar P. Reddy
Sekhar P. Reddy University of Illinois at Chicago
James P. Kehrer
James P. Kehrer University of Alberta
Edward Gabrielson
Edward Gabrielson Johns Hopkins University School of Medicine
Patrick N. Breysse
Patrick N. Breysse Johns Hopkins University
Virinder S. Parmar
Virinder S. Parmar City University of New York
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia

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