What is she best known for?
The fields of study she is best known for:
Her primary areas of study are Cell biology, Transcription factor, Biochemistry, Gene and KEAP1.
Her Cell biology study combines topics in areas such as Autophagy, Oxidative phosphorylation, Carcinogenesis and Enzyme.
The various areas that Hozumi Motohashi examines in her Transcription factor study include Regulation of gene expression and Downregulation and upregulation.
Hozumi Motohashi works mostly in the field of Biochemistry, limiting it down to topics relating to Cancer cell and, in certain cases, Anabolism, Signal transduction and Cytoprotection, as a part of the same area of interest.
Her work in Gene tackles topics such as Molecular biology which are related to areas like Gene expression profiling.
Her KEAP1 research is multidisciplinary, relying on both Phenotype and Cancer research.
Her most cited work include:
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 (1386 citations)
- A promoter-level mammalian expression atlas (1307 citations)
- Nrf2-Keap1 defines a physiologically important stress response mechanism. (1222 citations)
What are the main themes of her work throughout her whole career to date?
Cell biology, Transcription factor, Molecular biology, KEAP1 and Biochemistry are her primary areas of study.
Her biological study spans a wide range of topics, including Autophagy and Cell growth.
Her Transcription factor study integrates concerns from other disciplines, such as Regulation of gene expression and Cellular differentiation.
The study incorporates disciplines such as Gene expression, Transgene, MafG Transcription Factor, Mutant and Transcription in addition to Molecular biology.
Her work carried out in the field of Transgene brings together such families of science as Haematopoiesis and Immunology.
Her studies deal with areas such as Cancer research, Endocrinology, Cytoprotection, Cancer cell and Internal medicine as well as KEAP1.
She most often published in these fields:
- Cell biology (28.86%)
- Transcription factor (26.87%)
- Molecular biology (25.87%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (28.86%)
- Cancer research (14.43%)
- KEAP1 (16.92%)
In recent papers she was focusing on the following fields of study:
Hozumi Motohashi mostly deals with Cell biology, Cancer research, KEAP1, Carcinogenesis and Oxidative stress.
Her Cell biology study combines topics from a wide range of disciplines, such as Regulation of gene expression, Oxidative phosphorylation and Transcription factor.
Her Transcription factor research incorporates elements of Ubiquitin and Proteasome.
Her KEAP1 research focuses on Cytoprotection and how it connects with Hyperactivation and Cellular differentiation.
Her Carcinogenesis research incorporates themes from Cancer cell and Cancer Model.
The Oxidative stress study combines topics in areas such as Biogenesis, ATP synthase and Antioxidant.
Between 2017 and 2021, her most popular works were:
- The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis (338 citations)
- The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis (338 citations)
- NRF2 addiction in cancer cells. (102 citations)
In her most recent research, the most cited papers focused on:
Hozumi Motohashi mainly investigates Cell biology, Cancer research, Carcinogenesis, Cancer cell and Oxidative phosphorylation.
Hozumi Motohashi frequently studies issues relating to Ubiquitin and Cell biology.
Her research investigates the connection between Cancer research and topics such as Cancer that intersect with issues in Cytoprotection and Cell growth.
Her work on KEAP1 expands to the thematically related Carcinogenesis.
She has researched Cancer cell in several fields, including Transcription factor, NRF1, Proteasome, HEK 293 cells and Beta-Transducin Repeat-Containing Proteins.
Her Oxidative phosphorylation research integrates issues from Redox homeostasis, Thiol, Homeostasis, Keap1 nrf2 and Regulation of gene expression.
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