Her primary areas of study are Cell biology, Transcription factor, Biochemistry, Gene and KEAP1. Her Cell biology study combines topics in areas such as Autophagy, Oxidative phosphorylation, Carcinogenesis and Enzyme. The various areas that Hozumi Motohashi examines in her Transcription factor study include Regulation of gene expression and Downregulation and upregulation.
Hozumi Motohashi works mostly in the field of Biochemistry, limiting it down to topics relating to Cancer cell and, in certain cases, Anabolism, Signal transduction and Cytoprotection, as a part of the same area of interest. Her work in Gene tackles topics such as Molecular biology which are related to areas like Gene expression profiling. Her KEAP1 research is multidisciplinary, relying on both Phenotype and Cancer research.
Cell biology, Transcription factor, Molecular biology, KEAP1 and Biochemistry are her primary areas of study. Her biological study spans a wide range of topics, including Autophagy and Cell growth. Her Transcription factor study integrates concerns from other disciplines, such as Regulation of gene expression and Cellular differentiation.
The study incorporates disciplines such as Gene expression, Transgene, MafG Transcription Factor, Mutant and Transcription in addition to Molecular biology. Her work carried out in the field of Transgene brings together such families of science as Haematopoiesis and Immunology. Her studies deal with areas such as Cancer research, Endocrinology, Cytoprotection, Cancer cell and Internal medicine as well as KEAP1.
Hozumi Motohashi mostly deals with Cell biology, Cancer research, KEAP1, Carcinogenesis and Oxidative stress. Her Cell biology study combines topics from a wide range of disciplines, such as Regulation of gene expression, Oxidative phosphorylation and Transcription factor. Her Transcription factor research incorporates elements of Ubiquitin and Proteasome.
Her KEAP1 research focuses on Cytoprotection and how it connects with Hyperactivation and Cellular differentiation. Her Carcinogenesis research incorporates themes from Cancer cell and Cancer Model. The Oxidative stress study combines topics in areas such as Biogenesis, ATP synthase and Antioxidant.
Hozumi Motohashi mainly investigates Cell biology, Cancer research, Carcinogenesis, Cancer cell and Oxidative phosphorylation. Hozumi Motohashi frequently studies issues relating to Ubiquitin and Cell biology. Her research investigates the connection between Cancer research and topics such as Cancer that intersect with issues in Cytoprotection and Cell growth.
Her work on KEAP1 expands to the thematically related Carcinogenesis. She has researched Cancer cell in several fields, including Transcription factor, NRF1, Proteasome, HEK 293 cells and Beta-Transducin Repeat-Containing Proteins. Her Oxidative phosphorylation research integrates issues from Redox homeostasis, Thiol, Homeostasis, Keap1 nrf2 and Regulation of gene expression.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Masaaki Komatsu;Hirofumi Kurokawa;Satoshi Waguri;Keiko Taguchi.
Nature Cell Biology (2010)
Nrf2-Keap1 defines a physiologically important stress response mechanism.
Hozumi Motohashi;Masayuki Yamamoto.
Trends in Molecular Medicine (2004)
A promoter-level mammalian expression atlas
Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Keiko Taguchi;Hozumi Motohashi;Masayuki Yamamoto.
Genes to Cells (2011)
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Yoichiro Mitsuishi;Keiko Taguchi;Yukie Kawatani;Tatsuhiro Shibata.
Cancer Cell (2012)
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
Eri H. Kobayashi;Takafumi Suzuki;Ryo Funayama;Takeshi Nagashima.
Nature Communications (2016)
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
Nobunao Wakabayashi;Ken Itoh;Junko Wakabayashi;Hozumi Motohashi.
Nature Genetics (2003)
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Yoshinobu Ichimura;Satoshi Waguri;Yu shin Sou;Shun Kageyama.
Molecular Cell (2013)
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
Mi Kyoung Kwak;Nobunao Wakabayashi;Nobunao Wakabayashi;Ken Itoh;Hozumi Motohashi.
Journal of Biological Chemistry (2003)
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.
Tatsuya Oyake;Ken Itoh;Hozumi Motohashi;Norio Hayashi.
Molecular and Cellular Biology (1996)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: