World's Best Scientists 2026 revealed!
Hozumi Motohashi

Hozumi Motohashi

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
34882
World Ranking
1024
National Ranking
78

Hozumi Motohashi publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Hozumi Motohashi sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 188 publications — 54th percentile

54% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Hozumi Motohashi D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Hozumi Motohashi sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 79 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Hozumi Motohashi is affiliated with Tohoku University in Japan and has an extensive publication record in the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans several subfields, prominently including molecular biology, biochemistry, physiology, cancer research, and epidemiology.

The scientist's work covers multiple topics, with particular focus on:

  • Genomics, phytochemicals, and oxidative stress
  • Sulfur compounds in biology
  • Glutathione transferases and polymorphisms
  • RNA modifications and cancer
  • Redox biology and oxidative stress
  • Coenzyme Q10 studies and effects
  • Autophagy in disease and therapy

Hozumi Motohashi has contributed to research published in various scientific venues. The most frequent publication venues include:

  • Free Radical Biology and Medicine
  • Redox Biology
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Biochemistry

Recent representative publications by Motohashi include:

  • "p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response," 2021, Nature Communications
  • "Ferroptosis in health and disease," 2024, Redox Biology
  • "Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study," 2020, Journal of Epidemiology
  • "Sulfide catabolism ameliorates hypoxic brain injury," 2021, Nature Communications
  • "Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers," 2020, Nature Communications

The scientist has collaborated frequently with several researchers, including:

  • Takaaki Akaike
  • Hiroki Sekine
  • Masanobu Morita
  • Shohei Murakami
  • Tetsuro Matsunaga

Best Publications

  • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

    Masaaki Komatsu;Hirofumi Kurokawa;Satoshi Waguri;Keiko Taguchi

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Nrf2-Keap1 defines a physiologically important stress response mechanism.

    Hozumi Motohashi;Masayuki Yamamoto

  • Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.

    Keiko Taguchi;Hozumi Motohashi;Masayuki Yamamoto

  • Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

    Eri H. Kobayashi;Takafumi Suzuki;Ryo Funayama;Takeshi Nagashima

  • Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

    Yoichiro Mitsuishi;Keiko Taguchi;Yukie Kawatani;Tatsuhiro Shibata

  • The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

    Masayuki Yamamoto;Thomas W. Kensler;Hozumi Motohashi

  • Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

    Yoshinobu Ichimura;Satoshi Waguri;Yu shin Sou;Shun Kageyama

  • Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

    Nobunao Wakabayashi;Ken Itoh;Junko Wakabayashi;Hozumi Motohashi

  • Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.

    Tomoaki Ida;Tomohiro Sawa;Hideshi Ihara;Yukihiro Tsuchiya

  • Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

    Mi Kyoung Kwak;Nobunao Wakabayashi;Nobunao Wakabayashi;Ken Itoh;Hozumi Motohashi

  • Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.

    Tatsuya Oyake;Ken Itoh;Hozumi Motohashi;Norio Hayashi

  • Toward clinical application of the Keap1–Nrf2 pathway

    Takafumi Suzuki;Hozumi Motohashi;Masayuki Yamamoto

  • Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity.

    Tae Yamamoto;Takafumi Suzuki;Akira Kobayashi;Junko Wakabayashi

  • Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors.

    Hozumi Motohashi;Tania O'Connor;Fumiki Katsuoka;James Douglas Engel

  • Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

    Takaaki Akaike;Tomoaki Ida;Fan-Yan Wei;Motohiro Nishida;Motohiro Nishida

  • Keap1 degradation by autophagy for the maintenance of redox homeostasis

    Keiko Taguchi;Nanako Fujikawa;Masaaki Komatsu;Tetsuro Ishii

  • Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

    Hiromi Okawa;Hozumi Motohashi;Akira Kobayashi;Hiroyuki Aburatani

  • The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism

    Yoichiro Mitsuishi;Hozumi Motohashi;Masayuki Yamamoto

  • Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1–Nrf2 regulatory pathway

    Hozumi Motohashi;Fumiki Katsuoka;James Douglas Engel;Masayuki Yamamoto

Frequent Co-Authors

Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Takaaki Akaike
Takaaki Akaike Tohoku University
James Douglas Engel
James Douglas Engel University of Michigan–Ann Arbor
Kazuhiko Igarashi
Kazuhiko Igarashi Tohoku University
Masaaki Komatsu
Masaaki Komatsu Juntendo University
Motohiro Nishida
Motohiro Nishida Kyushu University
Satoru Takahashi
Satoru Takahashi University of Tsukuba
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Kengo Kinoshita
Kengo Kinoshita Tohoku University
Takashi Suzuki
Takashi Suzuki Tohoku University

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