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Ken Itoh

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
47422
World Ranking
2271
National Ranking
139

Ken Itoh publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Ken Itoh sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 207 publications — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Ken Itoh D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Ken Itoh sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 91 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Ken Itoh is affiliated with Hirosaki University in Japan and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Physiology, Public Health, Environmental and Occupational Health, Cell Biology, and Nutrition and Dietetics.

Their research covers a variety of main topics, such as:

  • Genomics, phytochemicals, and oxidative stress
  • Nutritional Studies and Diet
  • Gut microbiota and health
  • Glutathione Transferases and Polymorphisms
  • Adipose Tissue and Metabolism
  • Endoplasmic Reticulum Stress and Disease
  • Advanced Glycation End Products research

Ken Itoh has collaborated frequently with co-authors including Tatsuya Mikami, Shuya Kasai, Koichi Murashita, Yota Tatara, and Shigeyuki Nakaji.

Their recent papers include:

  • "Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology," 2020, Biomolecules
  • "Mitochondrial Reactive Oxygen Species, Insulin Resistance, and Nrf2-Mediated Oxidative Stress Response-Toward an Actionable Strategy for Anti-Aging," 2023, Biomolecules
  • "Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice," 2020, PLoS Genetics
  • "Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction," 2021, Molecular and Cellular Biology
  • "Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness," 2020, Nutrients

Their publications are frequently featured in journals such as Scientific Reports, Nutrients, International Journal of Molecular Sciences, Biomolecules, and PLoS Genetics.

Best Publications

  • AN NRF2/SMALL MAF HETERODIMER MEDIATES THE INDUCTION OF PHASE II DETOXIFYING ENZYME GENES THROUGH ANTIOXIDANT RESPONSE ELEMENTS

    Ken Itoh;Tomoki Chiba;Satoru Takahashi;Tetsuro Ishii

  • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

    Ken Itoh;Nobunao Wakabayashi;Yasutake Katoh;Tetsuro Ishii

  • Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

    Albena T. Dinkova-Kostova;W. David Holtzclaw;Robert N. Cole;Ken Itoh

  • Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

    Tetsuro Ishii;Ken Itoh;Satoru Takahashi;Hideyo Sato

  • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

    Minerva Ramos-Gomez;Mi Kyoung Kwak;Patrick M. Dolan;Ken Itoh

  • Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

    Michael McMahon;Ken Itoh;Masayuki Yamamoto;John D. Hayes

  • Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles

    Ken Itoh;Kit I Tong;Masayuki Yamamoto

  • High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes.

    Akiko Enomoto;Ken Itoh;Eiko Nagayoshi;Junko Haruta

  • Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

    Nobunao Wakabayashi;Ken Itoh;Junko Wakabayashi;Hozumi Motohashi

  • Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles.

    Ken Itoh;Nobunao Wakabayashi;Yasutake Katoh;Tetsuro Ishii

  • Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

    Mi Kyoung Kwak;Nobunao Wakabayashi;Nobunao Wakabayashi;Ken Itoh;Hozumi Motohashi

  • Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.

    Mi Kyoung Kwak;Ken Itoh;Masayuki Yamamoto;Thomas W. Kensler

  • Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.

    Kit I. Tong;Yasutake Katoh;Hideki Kusunoki;Ken Itoh

  • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

    Yasutake Katoh;Ken Itoh;Eisaku Yoshida;Makoto Miyagishi

  • Discovery of the negative regulator of Nrf2, keap1: A historical overview

    Ken Itoh;Junsei Mimura;Masayuki Yamamoto

  • Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

    Paul Nioi;Michael McMahon;Ken Itoh;Masayuki Yamamoto

  • Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

    Simon A Chanas;Qing Jiang;Michael McMahon;Gail K McWalter

  • Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression.

    Hiromi Sasaki;Hideyo Sato;Kazumi Kuriyama-Matsumura;Kanako Sato

  • Transcription Factor Nrf2 Regulates Inflammation by Mediating the Effect of 15-Deoxy-Δ12,14-Prostaglandin J2

    Ken Itoh;Mie Mochizuki;Yukio Ishii;Tetsuro Ishii

  • Dimerization of Substrate Adaptors Can Facilitate Cullin-mediated Ubiquitylation of Proteins by a “Tethering” Mechanism A TWO-SITE INTERACTION MODEL FOR THE Nrf2-Keap1 COMPLEX

    Michael J. McMahon;Nerys Thomas;Ken Itoh;Masayuki Yamamoto

Frequent Co-Authors

Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Junsei Mimura
Junsei Mimura Hirosaki University
Tetsuro Ishii
Tetsuro Ishii University of Tsukuba
Satoru Takahashi
Satoru Takahashi University of Tsukuba
John D. Hayes
John D. Hayes University of Dundee
Tadaatsu Imaizumi
Tadaatsu Imaizumi Hirosaki University
Koichi Wakabayashi
Koichi Wakabayashi Hirosaki University
Koji Uchida
Koji Uchida University of Tokyo
Kei Satoh
Kei Satoh Hirosaki University
Akira Kobayashi
Akira Kobayashi Doshisha University

External Links

Personal website of Ken Itoh

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Best Scientists Citing Ken Itoh

Masayuki Yamamoto

Masayuki Yamamoto

Tohoku University

Publications: 349

Albena T. Dinkova-Kostova

Albena T. Dinkova-Kostova

University of Dundee

Publications: 155

Thomas W. Kensler

Thomas W. Kensler

Johns Hopkins University

Publications: 108

Donna D. Zhang

Donna D. Zhang

University of Arizona

Publications: 86

Hozumi Motohashi

Hozumi Motohashi

Tohoku University

Publications: 82

Shyam Biswal

Shyam Biswal

Johns Hopkins University

Publications: 74

John D. Hayes

John D. Hayes

University of Dundee

Publications: 72

Ah-Ng Tony Kong

Ah-Ng Tony Kong

Rutgers, The State University of New Jersey

Publications: 64

Jingbo Pi

Jingbo Pi

China Medical University

Publications: 63

Antonio Cuadrado

Antonio Cuadrado

Autonomous University of Madrid

Publications: 58

Kazuhiko Igarashi

Kazuhiko Igarashi

Tohoku University

Publications: 56

Jeffrey A. Johnson

Jeffrey A. Johnson

University of Wisconsin–Madison

Publications: 54

Xiao-Qiu Zhou

Xiao-Qiu Zhou

Sichuan Agricultural University

Publications: 51

Young-Joon Surh

Young-Joon Surh

Seoul National University

Publications: 51

Curtis D. Klaassen

Curtis D. Klaassen

University of Kansas

Publications: 49

Jefferson Y. Chan

Jefferson Y. Chan

University of Illinois at Urbana-Champaign

Publications: 44

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