Jeffrey A. Johnson

Research.com Recognitions

• 2019 - ACM Distinguished Member
• 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2006 - Fellow of Alfred P. Sloan Foundation
• 1963 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Best Publications

• Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis

  Jong-Min Lee;Marcus J. Calkins;Kaimin Chan;Yuet Wai Kan

  1096
  Citations

• Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

  Andy Y. Shih;Delinda A. Johnson;Gloria Wong;Andrew D. Kraft

  925
  Citations

• The Nrf2–ARE Pathway

  Jeffrey A. Johnson;Delinda A. Johnson;Andrew D. Kraft;Marcus J. Calkins

  768
  Citations

• Nuclear Factor E2-Related Factor 2-Dependent Antioxidant Response Element Activation by tert-Butylhydroquinone and Sulforaphane Occurring Preferentially in Astrocytes Conditions Neurons against Oxidative Insult

  Andrew D. Kraft;Delinda A. Johnson;Jeffrey A. Johnson

  764
  Citations

• Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease : Critical role for the astrocyte

  Pei Chun Chen;Marcelo R. Vargas;Amar K. Pani;Richard J. Smeyne

  665
  Citations

• Nrf2, a multi-organ protector?

  Jong Min Lee;Jiang Li;Delinda A. Johnson;Thor D. Stein

  598
  Citations

• The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

  Marcus J. Calkins;Delinda A. Johnson;Jessica A. Townsend;Marcelo R. Vargas

  576
  Citations

• Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.

  Marcelo R. Vargas;Delinda A. Johnson;Daniel W. Sirkis;Albee Messing

  524
  Citations

• Inhibition of 7,12-Dimethylbenz(a)anthracene- and N-Nitrosomethylurea-induced Rat Mammary Cancer by Dietary Flavonol Quercetin

  Ajit K. Verma;Jeffrey A. Johnson;Michael N. Gould;Martin A. Tanner

  492
  Citations

• Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways.

  Thor D. Stein;Jeffrey A. Johnson

  422
  Citations

• Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

  Thor D. Stein;Nicholas J. Anders;Charles DeCarli;Sic L. Chan

  417
  Citations

• NF-E2-related Factor-2 Mediates Neuroprotection against Mitochondrial Complex I Inhibitors and Increased Concentrations of Intracellular Calcium in Primary Cortical Neurons

  Jong-Min Lee;Andy Y. Shih;Timothy H. Murphy;Jeffrey A. Johnson

  380
  Citations

• Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.

  Delinda A. Johnson;Jeffrey A. Johnson

  377
  Citations

• The Nrf2-ARE cytoprotective pathway in astrocytes.

  Marcelo R. Vargas;Jeffrey A. Johnson

  360
  Citations

• Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

  Marcus J. Calkins;Rebekah J. Jakel;Delinda A. Johnson;Kaimin Chan

  355
  Citations

• Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes

  Melinda S. Yates;Masafumi Tauchi;Fumiki Katsuoka;Kathleen C. Flanders

  348
  Citations

• Phosphatidylinositol 3-Kinase, Not Extracellular Signal-regulated Kinase, Regulates Activation of the Antioxidant-Responsive Element in IMR-32 Human Neuroblastoma Cells

  Jong-Min Lee;Janean M. Hanson;Waihei A. Chu;Jeffrey A. Johnson

  341
  Citations

• Nrf2-mediated protection against 6-hydroxydopamine.

  Rebekah J. Jakel;Jessica A. Townsend;Andrew D. Kraft;Jeffrey A. Johnson

  332
  Citations

• Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.

  Jiang Li;Delinda Johnson;Marcus Calkins;Lynda Wright

  321
  Citations

• Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases.

  Li Gan;Jeffrey A. Johnson

  300
  Citations