2023 - Research.com Neuroscience in Canada Leader Award
1994 - Fellow of Alfred P. Sloan Foundation
His primary areas of study are Neuroscience, Glutathione, Biochemistry, Oxidative stress and Neuroprotection. His Neuroscience research incorporates themes from Stroke and Neurotransmission. His research investigates the connection between Glutathione and topics such as Glutamate receptor that intersect with issues in Intracellular.
Timothy H. Murphy works in the field of Biochemistry, namely Cystine. His Oxidative stress study combines topics in areas such as Antioxidant and Pharmacology. As a member of one scientific family, Timothy H. Murphy mostly works in the field of Neuroprotection, focusing on Cell biology and, on occasion, Programmed cell death, Gene expression, Microarray analysis techniques and Enhancer.
Timothy H. Murphy spends much of his time researching Neuroscience, Glutamate receptor, Cell biology, Biochemistry and Ischemia. His Neuroscience study is mostly concerned with Excitatory postsynaptic potential, Stimulation, Sensory system, Cortex and Somatosensory system. His Glutamate receptor study combines topics from a wide range of disciplines, such as NMDA receptor, Neurotoxicity and Premovement neuronal activity.
The concepts of his Cell biology study are interwoven with issues in Endocrinology, Internal medicine and Dendritic filopodia. His Ischemia research includes elements of Dendritic spine and Stroke. He works mostly in the field of Glutathione, limiting it down to concerns involving Oxidative stress and, occasionally, Neuroprotection.
The scientist’s investigation covers issues in Neuroscience, Cortex, Stroke, Optogenetics and Calcium imaging. His study focuses on the intersection of Neuroscience and fields such as Genetically modified mouse with connections in the field of Functional imaging. His Cortex research is multidisciplinary, incorporating perspectives in GCaMP and Anatomy.
The study incorporates disciplines such as Rehabilitation, Brain stimulation, Forelimb and Neuroprotection in addition to Stroke. The Optogenetics study combines topics in areas such as Motor cortex, Somatosensory system and Ischemia. He has included themes like Cerebral cortex, Voltage-sensitive dye and Nerve net in his Sensory system study.
Neuroscience, Optogenetics, Premovement neuronal activity, Glutamate receptor and Genetically modified mouse are his primary areas of study. His Neuroscience study frequently links to related topics such as Glutamatergic. His Optogenetics research is multidisciplinary, incorporating elements of Somatosensory system, Motor cortex, Voltage-sensitive dye, Cortex and Ischemia.
His research on Glutamate receptor concerns the broader Biochemistry. His work deals with themes such as Thalamus, Histology, Pathology, Small vessel and Hippocampus, which intersect with Genetically modified mouse. His studies in Neuroimaging integrate themes in fields like Cerebral cortex and Anatomy.
Plasticity during stroke recovery: from synapse to behaviour.
Timothy H. Murphy;Dale Corbett.
Nature Reviews Neuroscience (2009)
Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
Timothy H. Murphy;Masaomi Miyamoto;Antonio Sastre;Ronald L. Schnaar.
Oxidative stress induces apoptosis in embryonic cortical neurons.
Rajiv R. Ratan;Timothy H. Murphy;Jay M. Baraban.
Journal of Neurochemistry (2008)
Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress
Andy Y. Shih;Delinda A. Johnson;Gloria Wong;Andrew D. Kraft.
The Journal of Neuroscience (2003)
A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs
Masashi Umemiya;Nansheng Chen;Lynn A. Raymond;Timothy H. Murphy.
The Journal of Neuroscience (2001)
L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes.
Timothy H. Murphy;Paul F. Worley;Jay M. Baraban.
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.
Austen J. Milnerwood;Clare M. Gladding;Mahmoud A. Pouladi;Alexandra M. Kaufman.
Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake.
Timothy H. Murphy;Ronald L. Schnaar;Joseph T. Coyle.
The FASEB Journal (1990)
A Small-Molecule-Inducible Nrf2-Mediated Antioxidant Response Provides Effective Prophylaxis against Cerebral Ischemia In Vivo
Andy Y. Shih;Ping Li;Timothy H. Murphy.
The Journal of Neuroscience (2005)
In vivo voltage-sensitive dye imaging in adult mice reveals that somatosensory maps lost to stroke are replaced over weeks by new structural and functional circuits with prolonged modes of activation within both the peri-infarct zone and distant sites.
Craig E. Brown;Khatereh Aminoltejari;Heidi Erb;Ian R. Winship.
The Journal of Neuroscience (2009)
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