Timothy H. Murphy

Research.com Recognitions

• 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Plasticity during stroke recovery: from synapse to behaviour.

  Timothy H. Murphy;Dale Corbett

  2207
  Citations

• Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

  Timothy H. Murphy;Masaomi Miyamoto;Antonio Sastre;Ronald L. Schnaar

  1224
  Citations

• Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

  Andy Y. Shih;Delinda A. Johnson;Gloria Wong;Andrew D. Kraft

  925
  Citations

• Oxidative stress induces apoptosis in embryonic cortical neurons.

  Rajiv R. Ratan;Timothy H. Murphy;Jay M. Baraban

  882
  Citations

• A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs

  Masashi Umemiya;Nansheng Chen;Lynn A. Raymond;Timothy H. Murphy

  675
  Citations

• Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.

  Austen J. Milnerwood;Clare M. Gladding;Mahmoud A. Pouladi;Alexandra M. Kaufman

  609
  Citations

• L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes.

  Timothy H. Murphy;Paul F. Worley;Jay M. Baraban

  550
  Citations

• Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake.

  Timothy H. Murphy;Ronald L. Schnaar;Joseph T. Coyle

  520
  Citations

• A Small-Molecule-Inducible Nrf2-Mediated Antioxidant Response Provides Effective Prophylaxis against Cerebral Ischemia In Vivo

  Andy Y. Shih;Ping Li;Timothy H. Murphy

  510
  Citations

• Extensive Turnover of Dendritic Spines and Vascular Remodeling in Cortical Tissues Recovering from Stroke

  Craig E. Brown;Ping Li;Jamie D. Boyd;Kerry R. Delaney

  456
  Citations

• Spontaneous cortical activity alternates between motifs defined by regional axonal projections

  Majid H Mohajerani;Allen W Chan;Mostafa Mohsenvand;Jeffrey LeDue

  447
  Citations

• In vivo voltage-sensitive dye imaging in adult mice reveals that somatosensory maps lost to stroke are replaced over weeks by new structural and functional circuits with prolonged modes of activation within both the peri-infarct zone and distant sites.

  Craig E. Brown;Khatereh Aminoltejari;Heidi Erb;Ian R. Winship

  447
  Citations

• Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.

  Andy Y. Shih;Heidi Erb;Xiaojian Sun;Shigenobu Toda

  385
  Citations

• NF-E2-related Factor-2 Mediates Neuroprotection against Mitochondrial Complex I Inhibitors and Increased Concentrations of Intracellular Calcium in Primary Cortical Neurons

  Jong-Min Lee;Andy Y. Shih;Timothy H. Murphy;Jeffrey A. Johnson

  380
  Citations

• Induction of the Nrf2-driven Antioxidant Response Confers Neuroprotection during Mitochondrial Stress in Vivo

  Andy Y. Shih;Sophie Imbeault;Vilte Barakauskas;Heidi Erb

  320
  Citations

• Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

  Rajiv R. Ratan;Timothy H. Murphy;Jay M. Baraban

  320
  Citations

• Rapid Reversible Changes in Dendritic Spine Structure In Vivo Gated by the Degree of Ischemia

  Shengxiang Zhang;Jamie Boyd;Kerry Delaney;Timothy H. Murphy

  318
  Citations

• Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line.

  M Miyamoto;T H Murphy;R L Schnaar;J T Coyle

  317
  Citations

• Two-Photon Imaging of Stroke Onset In Vivo Reveals That NMDA-Receptor Independent Ischemic Depolarization Is the Major Cause of Rapid Reversible Damage to Dendrites and Spines

  Timothy H. Murphy;Ping Li;Kellen Betts;Richard Liu

  307
  Citations

• Mirrored Bilateral Slow-Wave Cortical Activity within Local Circuits Revealed by Fast Bihemispheric Voltage-Sensitive Dye Imaging in Anesthetized and Awake Mice

  Majid H. Mohajerani;David A. McVea;Matthew Fingas;Timothy H. Murphy

  297
  Citations