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D-Index & Metrics

Neuroscience

D-Index
94
Citations
30988
World Ranking
950
National Ranking
510

Research.com Recognitions

  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2010 - National Institutes of Health Director's Pioneer Award

Overview

David Kleinfeld is a researcher affiliated with the University of California, San Diego in the United States. Their work primarily spans the fields of Neuroscience and Medicine, with a specific focus on subfields including Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging, Cellular and Molecular Neuroscience, Molecular Biology, and Neurology.

Their research topics cover a variety of specialized areas such as:

  • Neural dynamics and brain function
  • Neuroscience of respiration and sleep
  • Advanced MRI Techniques and Applications
  • Neuroscience and Neuropharmacology Research
  • Photoreceptor and optogenetics research
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications

David Kleinfeld has authored numerous publications, with frequent appearances in several scientific journals. The venues where their work is often published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Current Biology
  • Nature Methods
  • Nature

Among the recent papers contributed to or co-authored by David Kleinfeld are:

  • Cerebrospinal fluid influx drives acute ischemic tissue swelling (2020, Science)
  • Ultra-slow Oscillations in fMRI and Resting-State Connectivity: Neuronal and Vascular Contributions and Technical Confounds (2020, Neuron)
  • Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon (2021, Neuron)
  • Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission (2023, Nature Methods)
  • Brain microvasculature has a common topology with local differences in geometry that match metabolic load (2021, Neuron)

Kleinfeld frequently collaborates with a number of co-authors, including Rui Liu, Beth Friedman, Céline Matéo, Martin Deschênes, and Xin Yu.

Over the course of their career, David Kleinfeld has received recognition through various awards such as the National Institutes of Health Director's Pioneer Award (2010), Fellowship of the American Association for the Advancement of Science (AAAS) in 2012, and Fellowship of the American Academy of Arts and Sciences in 2015.

Best Publications

  • In vivo dendritic calcium dynamics in neocortical pyramidal neurons

    Karel Svoboda;Winfried Denk;David Kleinfeld;David Kleinfeld;David W. Tank

  • Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex

    David Kleinfeld;Partha P. Mitra;Fritjof Helmchen;Winfried Denk

  • ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

    John Y Lin;Per Magne Knutsen;Arnaud Muller;David Kleinfeld

  • Controlled outgrowth of dissociated neurons on patterned substrates

    D Kleinfeld;KH Kahler;PE Hockberger

  • 'Where' and 'what' in the whisker sensorimotor system.

    Mathew E. Diamond;Mathew E. Diamond;Moritz von Heimendahl;Moritz von Heimendahl;Per Magne Knutsen;David Kleinfeld

  • Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels.

    Philbert S. Tsai;John P. Kaufhold;Pablo Blinder;Beth Friedman

  • The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow

    Pablo Blinder;Philbert S Tsai;John P Kaufhold;John P Kaufhold;Per M Knutsen

  • Traveling Electrical Waves in Cortex: Insights from Phase Dynamics and Speculation on a Computational Role

    G.Bard Ermentrout;David Kleinfeld

  • Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain

    Andy Y Shih;Jonathan D Driscoll;Patrick J Drew;Nozomi Nishimura

  • Anatomical and functional imaging of neurons using 2-photon laser scanning microscopy

    W. Denk;K. R. Delaney;A. Gelperin;D. Kleinfeld

  • Quality metrics to accompany spike sorting of extracellular signals.

    Daniel N. Hill;Samar B. Mehta;David Kleinfeld

  • Automatic sorting of multiple unit neuronal signals in the presence of anisotropic and non-Gaussian variability.

    Michale S. Fee;Partha P. Mitra;David Kleinfeld

  • Rhythmic whisking by rat: retraction as well as protraction of the vibrissae is under active muscular control.

    Rune W. Berg;David Kleinfeld

  • Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.

    Chris B Schaffer;Beth Friedman;Beth Friedman;Nozomi Nishimura;Lee F Schroeder

  • Active sensation: insights from the rodent vibrissa sensorimotor system.

    David Kleinfeld;Ehud Ahissar;Mathew E Diamond

  • Chronic optical access through a polished and reinforced thinned skull

    Patrick James Drew;Andy Y. Shih;Jonathan D. Driscoll;Per Magne Knutsen

  • Suppressed Neuronal Activity and Concurrent Arteriolar Vasoconstriction May Explain Negative Blood Oxygenation Level-Dependent Signal

    Anna Devor;Peifang Tian;Nozomi Nishimura;Ivan C. Teng

  • Cerebrospinal fluid influx drives acute ischemic tissue swelling

    Humberto Mestre;Ting Du;Ting Du;Amanda M Sweeney;Guojun Liu;Guojun Liu

  • Penetrating arterioles are a bottleneck in the perfusion of neocortex.

    Nozomi Nishimura;Chris B. Schaffer;Beth Friedman;Patrick D. Lyden

  • Sequential state generation by model neural networks

    David Kleinfeld

  • Visual stimuli induce waves of electrical activity in turtle cortex

    J. C. Prechtl;L. B. Cohen;L. B. Cohen;B. Pesaran;P. P. Mitra

  • The smallest stroke: Occlusion of one penetrating vessel leads to infarction and a cognitive deficit

    Andy Y Shih;Pablo Blinder;Pablo Blinder;Philbert S Tsai;Beth Friedman

  • Correction: In the artide Suppressed Neuronal Activity and Concurrent Arteriolar Vasoconstriction May Explain Negative Blood Oxygenation Level-Dependent Signal

    Anna Devor;Peifang Tian;Nozomi Nishimura;Ivan C. Teng

Frequent Co-Authors

Martin Deschênes
Martin Deschênes Université Laval
Anna Devor
Anna Devor Boston University
Patrick J. Drew
Patrick J. Drew Pennsylvania State University
David A. Boas
David A. Boas Boston University
Anders M. Dale
Anders M. Dale J. Craig Venter Institute
Klaus Scheffler
Klaus Scheffler Max Planck Society
Harvey J. Karten
Harvey J. Karten University of California, San Diego
Ehud Ahissar
Ehud Ahissar Weizmann Institute of Science

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