Edward S. Boyden

Research.com Recognitions

• 2019 - Member of the National Academy of Sciences
• 2019 - Warren Alpert Foundation Prize For the development of optogenetics as a way to control the activity of specific circuits in the nervous system, to determine their function and ultimately to control them to treat neurological and psychiatric disorders.
• 2018 - Canada Gairdner International Award
• 2017 - Fellow, National Academy of Inventors
• 2017 - Fellow of the American Academy of Arts and Sciences
• 2016 - Breakthrough Prize in Life Sciences for the development and implementation of optogenetics – the programming of neurons to express light-activated ion channels and pumps, so that their electrical activity can be controlled by light.
• 2015 - BBVA Foundation Frontiers of Knowledge Award
• 2013 - National Institutes of Health Director's Pioneer Award
• 2013 - The Brain Prize, Lundbeck Foundation For their invention and refinement of optogenetics. This revolutionary technique allows genetically specified populations of neurons to be turned on or off with light, offering not only the ability to elucidate the characteristics of normal and abnormal neural circuitry but also new approaches to treatment of brain disorders
• 2011 - Perl-UNC Prize, University of North Carolina at Chapel Hill Development and Application of Optogenetics for Studying Neural Circuit Functions.
• 2008 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Millisecond-timescale, genetically targeted optical control of neural activity.

  Edward S Boyden;Feng Zhang;Ernst Bamberg;Georg Nagel

  5909
  Citations

• Independent optical excitation of distinct neural populations

  Nathan C Klapoetke;Yasunobu Murata;Sung Soo Kim;Stefan R Pulver

  2531
  Citations

• A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

  Linda Madisen;Tianyi Mao;Tianyi Mao;Henner Koch;Jia Min Zhuo

  1531
  Citations

• High-performance genetically targetable optical neural silencing by light-driven proton pumps

  Brian Y. Chow;Xue Han;Xue Han;Allison S. Dobry;Allison S. Dobry;Xiaofeng Qian;Xiaofeng Qian

  1432
  Citations

• Gamma frequency entrainment attenuates amyloid load and modifies microglia

  Hannah F. Iaccarino;Annabelle C. Singer;Anthony J. Martorell;Anthony J. Martorell;Andrii Rudenko;Andrii Rudenko

  1301
  Citations

• Cell diversity and network dynamics in photosensitive human brain organoids

  Giorgia Quadrato;Giorgia Quadrato;Tuan Nguyen;Tuan Nguyen;Evan Z. Macosko;Evan Z. Macosko;John L. Sherwood;John L. Sherwood

  1301
  Citations

• Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.

  Linda Madisen;Aleena R. Garner;Daisuke Shimaoka;Amy S. Chuong

  1200
  Citations

• Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

  Nir Grossman;David Bono;Nina Dedic;Suhasa B. Kodandaramaiah

  1026
  Citations

• Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

  Robert Prevedel;Young-Gyu Yoon;Maximilian Hoffmann;Maximilian Hoffmann;Maximilian Hoffmann;Nikita Pak

  933
  Citations

• Channelrhodopsin-2 and optical control of excitable cells

  Feng Zhang;Li-Ping Wang;Edward S Boyden;Karl Deisseroth

  918
  Citations

• A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

  Tanya L. Daigle;Linda Madisen;Travis A. Hage;Matthew T. Valley

  878
  Citations

• All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

  Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Nathan Klapoetke

  870
  Citations

• Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution.

  Xue Han;Edward S. Boyden

  845
  Citations

• Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

  Anthony J. Martorell;Anthony J. Martorell;Abigail L. Paulson;Ho Jun Suk;Ho Jun Suk;Fatema Abdurrob;Fatema Abdurrob

  728
  Citations

• Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

  Paul W Tillberg;Fei Chen;Kiryl D Piatkevich;Yongxin Zhao

  722
  Citations

• Drug discovery: a jump-start for electroceuticals.

  Kristoffer Famm;Brian Litt;Kevin J. Tracey;Edward S. Boyden

  718
  Citations

• Activation of specific interneurons improves V1 feature selectivity and visual perception

  Seung-Hee Lee;Alex C. Kwan;Siyu Zhang;Victoria Phoumthipphavong

  707
  Citations

• Noninvasive optical inhibition with a red-shifted microbial rhodopsin

  Amy S. Chuong;Mitra L. Miri;Volker Busskamp;Gillian A.C. Matthews

  651
  Citations

• A High-Light Sensitivity Optical Neural Silencer: Development and Application to Optogenetic Control of Non-Human Primate Cortex

  Xue Han;Brian Y. Chow;Huihui Zhou;Nathan C. Klapoetke

  618
  Citations

• Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain.

  Xue Han;Xiaofeng Qian;Jacob G. Bernstein;Hui-hui Zhou

  608
  Citations

• All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

  Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Christopher A Werley

  0
  Citations

• A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

  Linda Madisen;Tianyi Mao;Henner Koch;Jia-min Zhuo

  0
  Citations