World's Best Scientists 2026 revealed!
Edward S. Boyden

Edward S. Boyden

D-Index & Metrics

Neuroscience

D-Index
103
Citations
52342
World Ranking
679
National Ranking
378

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences
  • 2019 - Warren Alpert Foundation Prize For the development of optogenetics as a way to control the activity of specific circuits in the nervous system, to determine their function and ultimately to control them to treat neurological and psychiatric disorders.
  • 2018 - Canada Gairdner International Award
  • 2017 - Fellow, National Academy of Inventors
  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2016 - Breakthrough Prize in Life Sciences for the development and implementation of optogenetics – the programming of neurons to express light-activated ion channels and pumps, so that their electrical activity can be controlled by light.
  • 2015 - BBVA Foundation Frontiers of Knowledge Award
  • 2013 - National Institutes of Health Director's Pioneer Award
  • 2013 - The Brain Prize, Lundbeck Foundation For their invention and refinement of optogenetics. This revolutionary technique allows genetically specified populations of neurons to be turned on or off with light, offering not only the ability to elucidate the characteristics of normal and abnormal neural circuitry but also new approaches to treatment of brain disorders
  • 2011 - Perl-UNC Prize, University of North Carolina at Chapel Hill Development and Application of Optogenetics for Studying Neural Circuit Functions.
  • 2008 - Fellow of Alfred P. Sloan Foundation

Overview

Edward S. Boyden is affiliated with MIT in the United States. Their research contributions span the fields of Biochemistry, Genetics and Molecular Biology as well as Neuroscience. Key subfields include Molecular Biology, Cellular and Molecular Neuroscience, Biophysics, Cognitive Neuroscience, and Structural Biology.

The scientist's work covers a range of topics, notably:

  • Advanced Fluorescence Microscopy Techniques
  • Cell Image Analysis Techniques
  • Neuroscience and Neural Engineering
  • Neural dynamics and brain function
  • Photoreceptor and optogenetics research
  • Advanced Electron Microscopy Techniques and Applications
  • Single-cell and spatial transcriptomics

Edward S. Boyden has published in several frequent venues, among them:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • eLife
  • Nature
  • Neuron

Recent papers include:

  • "Autism genes converge on asynchronous development of shared neuron classes", 2022, Nature
  • "Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems", 2021, Science
  • "Multisensory gamma stimulation promotes glymphatic clearance of amyloid", 2024, Nature
  • "In situ genome sequencing resolves DNA sequence and structure in intact biological samples", 2021, Science
  • "Non-invasive temporal interference electrical stimulation of the human hippocampus", 2023, Nature Neuroscience

Frequent co-authors in their research collaborations are:

  • Kiryl D. Piatkevich
  • Demian Park
  • Daniel Goodwin
  • Fei Chen
  • Li-Huei Tsai

Awards received by Edward S. Boyden include:

  • Warren Alpert Foundation Prize (2019) for developing optogenetics to control neural circuit activity and its applications in neurological and psychiatric disorders
  • Member of the National Academy of Sciences (2019)
  • Canada Gairdner International Award (2018)
  • Fellow, National Academy of Inventors (2017)
  • Fellow of the American Academy of Arts and Sciences (2017)
  • Breakthrough Prize in Life Sciences (2016) for the development and implementation of optogenetics
  • BBVA Foundation Frontiers of Knowledge Award (2015)
  • The Brain Prize, Lundbeck Foundation (2013) for invention and refinement of optogenetics
  • National Institutes of Health Director's Pioneer Award (2013)
  • Perl-UNC Prize, University of North Carolina at Chapel Hill (2011) for work in optogenetics
  • Fellow of Alfred P. Sloan Foundation (2008)

Best Publications

  • Millisecond-timescale, genetically targeted optical control of neural activity.

    Edward S Boyden;Feng Zhang;Ernst Bamberg;Georg Nagel

  • Independent optical excitation of distinct neural populations

    Nathan C Klapoetke;Yasunobu Murata;Sung Soo Kim;Stefan R Pulver

  • A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

    Linda Madisen;Tianyi Mao;Tianyi Mao;Henner Koch;Jia Min Zhuo

  • High-performance genetically targetable optical neural silencing by light-driven proton pumps

    Brian Y. Chow;Xue Han;Xue Han;Allison S. Dobry;Allison S. Dobry;Xiaofeng Qian;Xiaofeng Qian

  • Gamma frequency entrainment attenuates amyloid load and modifies microglia

    Hannah F. Iaccarino;Annabelle C. Singer;Anthony J. Martorell;Anthony J. Martorell;Andrii Rudenko;Andrii Rudenko

  • Cell diversity and network dynamics in photosensitive human brain organoids

    Giorgia Quadrato;Giorgia Quadrato;Tuan Nguyen;Tuan Nguyen;Evan Z. Macosko;Evan Z. Macosko;John L. Sherwood;John L. Sherwood

  • Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.

    Linda Madisen;Aleena R. Garner;Daisuke Shimaoka;Amy S. Chuong

  • Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

    Nir Grossman;David Bono;Nina Dedic;Suhasa B. Kodandaramaiah

  • Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

    Robert Prevedel;Young-Gyu Yoon;Maximilian Hoffmann;Maximilian Hoffmann;Maximilian Hoffmann;Nikita Pak

  • Channelrhodopsin-2 and optical control of excitable cells

    Feng Zhang;Li-Ping Wang;Edward S Boyden;Karl Deisseroth

  • A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

    Tanya L. Daigle;Linda Madisen;Travis A. Hage;Matthew T. Valley

  • All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

    Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Nathan Klapoetke

  • Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution.

    Xue Han;Edward S. Boyden

  • Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

    Anthony J. Martorell;Anthony J. Martorell;Abigail L. Paulson;Ho Jun Suk;Ho Jun Suk;Fatema Abdurrob;Fatema Abdurrob

  • Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

    Paul W Tillberg;Fei Chen;Kiryl D Piatkevich;Yongxin Zhao

  • Drug discovery: a jump-start for electroceuticals.

    Kristoffer Famm;Brian Litt;Kevin J. Tracey;Edward S. Boyden

  • Activation of specific interneurons improves V1 feature selectivity and visual perception

    Seung-Hee Lee;Alex C. Kwan;Siyu Zhang;Victoria Phoumthipphavong

  • Noninvasive optical inhibition with a red-shifted microbial rhodopsin

    Amy S. Chuong;Mitra L. Miri;Volker Busskamp;Gillian A.C. Matthews

  • A High-Light Sensitivity Optical Neural Silencer: Development and Application to Optogenetic Control of Non-Human Primate Cortex

    Xue Han;Brian Y. Chow;Huihui Zhou;Nathan C. Klapoetke

  • Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain.

    Xue Han;Xiaofeng Qian;Jacob G. Bernstein;Hui-hui Zhou

  • All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

    Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Christopher A Werley

  • A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

    Linda Madisen;Tianyi Mao;Henner Koch;Jia-min Zhuo

Frequent Co-Authors

George M. Church
George M. Church Harvard University
Konrad P. Kording
Konrad P. Kording University of Pennsylvania
Karl Deisseroth
Karl Deisseroth Stanford University
Nancy Kopell
Nancy Kopell Boston University
Joshua S. Shimony
Joshua S. Shimony Washington University in St. Louis
Gane Ka-Shu Wong
Gane Ka-Shu Wong University of Alberta

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Edward S. Boyden

Trending Scientists