2013 - Fellow of the American Association for the Advancement of Science (AAAS)
His scientific interests lie mostly in Genetics, Open reading frame, Genome, Gene and Ribosome. His study connects Computational biology and Genetics. He combines subjects such as Five prime untranslated region, Codon usage bias and Fungal protein with his study of Open reading frame.
Matthew S. Sachs works mostly in the field of Genome, limiting it down to topics relating to Neurospora crassa and, in certain cases, Schizosaccharomyces pombe. His Phylogenetics, Ribosomal RNA, Phylogenetic tree and 16S ribosomal RNA study in the realm of Gene connects with subjects such as Methanosarcinaceae. His Ribosome study integrates concerns from other disciplines, such as Stop codon, MRNA degradation and Cell biology.
Matthew S. Sachs focuses on Genetics, Neurospora crassa, Ribosome, Cell biology and Translation. His Genetics and Open reading frame, Genome, Stop codon, Five prime untranslated region and Fungal genetics investigations all form part of his Genetics research activities. His Neurospora crassa research is classified as research in Gene.
His study in Ribosome is interdisciplinary in nature, drawing from both Operon and Protein biosynthesis. His studies in Cell biology integrate themes in fields like Circadian clock, Gene expression and Translational frameshift. His research investigates the link between Translation and topics such as Transfer RNA that cross with problems in Nucleotide.
His primary areas of study are Cell biology, Ribosome, Genetics, Translation and Protein biosynthesis. His Cell biology research is multidisciplinary, relying on both Neurospora crassa, Gene and Anatomy. When carried out as part of a general Neurospora crassa research project, his work on Neurospora is frequently linked to work in Elongation Factor-2 Kinase, therefore connecting diverse disciplines of study.
His research investigates the connection between Ribosome and topics such as Operon that intersect with issues in Release factor, Ribosomal RNA, 23S ribosomal RNA and 5.8S ribosomal RNA. Matthew S. Sachs combines topics linked to Computational biology with his work on Genetics. Matthew S. Sachs has researched Protein biosynthesis in several fields, including Integrated stress response, Eukaryotic translation, Messenger RNA and Gene expression.
His primary scientific interests are in Cell biology, Ribosome, Biochemistry, Eukaryotic translation and Protein biosynthesis. The various areas that he examines in his Cell biology study include Translation, Messenger RNA, Molecular biology and Neurospora crassa. His Ribosome research is multidisciplinary, incorporating elements of Ribosomal RNA, Transfer RNA, Transcription Factor CHOP and Transcriptional attenuation.
His Eukaryotic translation study incorporates themes from Integrated stress response, Translation reinitiation and Coding region. To a larger extent, Matthew S. Sachs studies Genetics with the aim of understanding Coding region. Matthew S. Sachs has included themes like Ribosome profiling, Computational biology, Codon usage bias and Start codon in his Open reading frame study.
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The genome sequence of the filamentous fungus Neurospora crassa
James E. Galagan;Sarah E. Calvo;Katherine A. Borkovich;Eric U. Selker.
Nature (2003)
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
James E. Galagan;Sarah E. Calvo;Christina Cuomo;Li Jun Ma.
Nature (2005)
Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism
Katherine A. Borkovich;Lisa A. Alex;Oded Yarden;Michael Freitag.
Microbiology and Molecular Biology Reviews (2004)
Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding
Chien Hung Yu;Yunkun Dang;Zhipeng Zhou;Cheng Wu.
Molecular Cell (2015)
Early nonsense: mRNA decay solves a translational problem
Nadia Amrani;Matthew S. Sachs;Allan Jacobson.
Nature Reviews Molecular Cell Biology (2006)
Non-optimal codon usage affects expression, structure and function of clock protein FRQ
Mian Zhou;Jinhu Guo;Jinhu Guo;Joonseok Cha;Michael Chae.
Nature (2013)
Partial gene sequences for the A subunit of methyl-coenzyme M reductase (mcrI) as a phylogenetic tool for the family Methanosarcinaceae.
Erik Springer;Matthew S. Sachs;Carl R. Woese;David R. Boone.
International Journal of Systematic and Evolutionary Microbiology (1995)
The Neurospora Compendium: Chromosomal Loci
David D. Perkins;Alan Radford;Matthew S. Sachs.
(2000)
Redundancy of the Two Dicer Genes in Transgene-Induced Posttranscriptional Gene Silencing in Neurospora crassa
Caterina Catalanotto;Massimiliano Pallotta;Paul ReFalo;Matthew S. Sachs.
Molecular and Cellular Biology (2004)
Enabling a community to dissect an organism: overview of the Neurospora functional genomics project.
Jay C. Dunlap;Katherine A. Borkovich;Matthew R. Henn;Gloria E. Turner.
Advances in Genetics (2007)
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