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Genetics

D-Index
57
Citations
13056
World Ranking
3399
National Ranking
1469

Overview

Yi Liu is a researcher affiliated with The University of Texas Southwestern Medical Center in the United States. Their academic work is primarily situated within the field of Biochemistry, Genetics, and Molecular Biology, with a specific focus on Molecular Biology as well as Genetics and Plant Science. Their research contributions span multiple related subfields, including Endocrine and Autonomic Systems and Immunology.

Their publications often explore the molecular mechanisms underlying RNA and protein synthesis, epigenetics, and cancer biology. Key topics addressed in their work include:

  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Circadian rhythm and melatonin
  • Genomics and Phylogenetic Studies
  • Cancer-related gene regulation

Yi Liu has published extensively, with a strong presence in specific outlets such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), PubMed, Proceedings of the National Academy of Sciences, and Nucleic Acids Research. Notable recent papers include:

  • A code within the genetic code: codon usage regulates co-translational protein folding, 2020, Cell Communication and Signaling
  • Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding, 2021, Annual Review of Biochemistry

Frequent collaborators in their research group and joint publications have included Ying Xu, Qun He, Fangzhou Zhao, Pancheng Xie, and Zhongtao Gai. These collaborative efforts contribute to a broad understanding of genetic code regulation, protein folding, and translation dynamics.

Yi Liu's research not only engages with classical molecular biology questions but also addresses complex regulatory layers involving codon usage and its impact on protein synthesis and folding. Research outputs have garnered significant attention, with a number of papers highly cited within the scientific community.

Best Publications

  • White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter.

    Allan C. Froehlich;Yi Liu;Jennifer J. Loros;Jay C. Dunlap

  • Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding

    Chien Hung Yu;Yunkun Dang;Zhipeng Zhou;Cheng Wu

  • White Collar-1, a DNA Binding Transcription Factor and a Light Sensor

    Qiyang He;Ping Cheng;Yuhong Yang;Lixing Wang

  • Non-optimal codon usage affects expression, structure and function of clock protein FRQ

    Mian Zhou;Jinhu Guo;Jinhu Guo;Joonseok Cha;Michael Chae

  • Alternative Initiation of Translation and Time-Specific Phosphorylation Yield Multiple Forms of the Essential Clock Protein FREQUENCY

    Norman Y. Garceau;Yi Liu;Jennifer J. Loros;Jay C. Dunlap

  • Codon usage is an important determinant of gene expression levels largely through its effects on transcription

    Zhipeng Zhou;Yunkun Dang;Mian Zhou;Lin Li

  • Diverse Pathways Generate MicroRNA-like RNAs and Dicer-Independent Small Interfering RNAs in Fungi

    Heng Chi Lee;Liande Li;Weifeng Gu;Zhihong Xue

  • qiRNA is a new type of small interfering RNA induced by DNA damage

    Heng Chi Lee;Shwu Shin Chang;Swati Choudhary;Antti P. Aalto

  • Thermally Regulated Translational Control of FRQ Mediates Aspects of Temperature Responses in the Neurospora Circadian Clock

    Yi Liu;Norman Y Garceau;Jennifer J Loros;Jay C Dunlap

  • Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock

    Ping Cheng;Yuhong Yang;Yi Liu

  • Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

    Yi Liu;Jennifer Loros;Jay C. Dunlap

  • How Temperature Changes Reset a Circadian Oscillator

    Yi Liu;Martha Merrow;Martha Merrow;Jennifer J. Loros;Jay C. Dunlap

  • Regulation of the Neurospora circadian clock by an RNA helicase

    Ping Cheng;Qun He;Qiyang He;Lixin Wang

  • Molecular mechanism of light responses in Neurospora: from light-induced transcription to photoadaptation

    Qiyang He;Yi Liu

  • RNA Interference Pathways in Fungi: Mechanisms and Functions

    Shwu Shin Chang;Zhenyu Zhang;Yi Liu

  • CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop

    Qun He;Qun He;Joonseok Cha;Qiyang He;Qiyang He;Heng Chi Lee

  • The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex

    Qun He;Ping Cheng;Qiyang He;Yi Liu

  • RNA interference in fungi: pathways, functions, and applications.

    Yunkun Dang;Qiuying Yang;Zhihong Xue;Yi Liu

  • PAS Domain-Mediated WC-1/WC-2 Interaction Is Essential for Maintaining the Steady-State Level of WC-1 and the Function of Both Proteins in Circadian Clock and Light Responses of Neurospora

    Ping Cheng;Yuhong Yang;Kevin H. Gardner;Yi Liu

  • FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation

    Qun He;Ping Cheng;Yuhong Yang;Qiyang He

Frequent Co-Authors

Jay C. Dunlap
Jay C. Dunlap Dartmouth College
Jennifer J. Loros
Jennifer J. Loros Dartmouth College
Igor V. Grigoriev
Igor V. Grigoriev Lawrence Berkeley National Laboratory
Matthew S. Sachs
Matthew S. Sachs Texas A&M University
Oded Yarden
Oded Yarden Hebrew University of Jerusalem
Kevin H. Gardner
Kevin H. Gardner City University of New York
Xiang Gao
Xiang Gao Nanjing University
Dennis H. Bamford
Dennis H. Bamford University of Helsinki
Craig C. Mello
Craig C. Mello University of Massachusetts Chan Medical School
Carl Hirschie Johnson
Carl Hirschie Johnson Vanderbilt University

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