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Biology and Biochemistry

D-Index
54
Citations
14771
World Ranking
15417
National Ranking
333

Overview

Antonio Castrillo is affiliated with the Spanish National Research Council in Spain. Their research focuses primarily on medicine, with particular attention to immunology and microbiology.

The scientist's contributions span various subfields including immunology, surgery, cancer research, molecular biology, and genetics. The main topics addressed in their work revolve around cholesterol and lipid metabolism, immune cells in cancer, interferon and immune responses, immune cell function and interaction, immune response and inflammation, neuroinflammation and neurodegeneration mechanisms, and the intersection of cancer, lipids, and metabolism.

Antonio Castrillo has published extensively in several notable venues. Frequent publication outlets include Frontiers in Immunology, Cellular and Molecular Life Sciences, Frontiers in Endocrinology, Scientific Reports, and Research Square.

  • Frontiers in Immunology
  • Cellular and Molecular Life Sciences
  • Frontiers in Endocrinology
  • Scientific Reports
  • Research Square

Their recent significant papers showcase a range of investigative angles within their research fields. These include:

  • "A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart," 2020, Cell
  • "Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development," 2020, Seminars in Cancer Biology
  • "Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment," 2020, Cancer Research
  • "Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells," 2020, Frontiers in Immunology
  • "Unraveling the interplay between iron homeostasis, ferroptosis and extramedullary hematopoiesis," 2022, Pharmacological Research

Collaboration is a key element of their research approach. Frequent co-authors include Lisardo Boscá, Juan Vladimir de la Rosa, Victoria Fernández-García, Silvia González-Ramos, and Paloma Martín-Sanz.

Best Publications

  • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

    Peter J. Tontonoz;Sean B. Joseph;Antonio Castrillo

  • Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance

    María Casanova-Acebes;Christophe Pitaval;Linnea A. Weiss;César Nombela-Arrieta

  • A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

    José A. Nicolás-Ávila;Ana V. Lechuga-Vieco;Lorena Esteban-Martínez;María Sánchez-Díaz

  • LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

    Sean B. Joseph;Michelle N. Bradley;Antonio Castrillo;Kevin W. Bruhn

  • Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue.

    Bryan A. Laffitte;Lily C. Chao;Jing Li;Robert Walczak

  • Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

    Noelia A-Gonzalez;Steven J. Bensinger;Cynthia Hong;Susana Beceiro

  • Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism.

    Antonio Castrillo;Sean B Joseph;Sagar A Vaidya;Margaret Haberland

  • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages.

    Antonio Castrillo;Sean B. Joseph;Chaitra Marathe;David J. Mangelsdorf

  • NUCLEAR RECEPTORS IN MACROPHAGE BIOLOGY: At the Crossroads of Lipid Metabolism and Inflammation

    Antonio Castrillo;Peter Tontonoz

  • Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ12,14-Prostaglandin J2 in Activated Murine Macrophages

    Antonio Castrillo;María José Díaz-Guerra;Sonsoles Hortelano;Paloma Martín-Sanz

  • A role for the apoptosis inhibitory factor AIM/Spα/Api6 in atherosclerosis development

    Satoko Arai;John M. Shelton;Mingyi Chen;Michelle N. Bradley

  • Induction of NR4A Orphan Nuclear Receptor Expression in Macrophages in Response to Inflammatory Stimuli

    Liming Pei;Antonio Castrillo;Mingyi Chen;Alexander Hoffmann

  • Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection.

    Antonio Castrillo;Daniel J. Pennington;Florian Otto;Peter J. Parker

  • DEL-1 promotes macrophage efferocytosis and clearance of inflammation

    Ioannis Kourtzelis;Ioannis Kourtzelis;Xiaofei Li;Ioannis Mitroulis;Ioannis Mitroulis;Daniel Grosser

  • The Increase in TNF-α Levels Is Implicated in NF-κB Activation and Inducible Nitric Oxide Synthase Expression in Brain Cortex after Immobilization Stress

    José L M Madrigal;Olivia Hurtado;María A Moro;Ignacio Lizasoain

  • Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77.

    Liming Pei;Antonio Castrillo;Peter Tontonoz

  • Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144

    Cristina M. Ramírez;Noemi Rotllan;Alexander V. Vlassov;Alexander V. Vlassov;Alberto Dávalos

  • Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms.

    José L. M. Madrigal;María A. Moro;Ignacio Lizasoain;Pedro Lorenzo

  • Phagocytosis imprints heterogeneity in tissue-resident macrophages.

    Noelia A-Gonzalez;Juan A. Quintana;Susana García-Silva;Marina Mazariegos

  • SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity

    Noelia Keiran;Victoria Ceperuelo-Mallafré;Enrique Calvo;Maria Isabel Hernández-Alvarez

Frequent Co-Authors

Lisardo Boscá
Lisardo Boscá Autonomous University of Madrid
Peter Tontonoz
Peter Tontonoz University of California, Los Angeles
Angel L. Corbí
Angel L. Corbí Spanish National Research Council
María A. Moro
María A. Moro Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.): Madrid, ES
Andrés Hidalgo
Andrés Hidalgo Yale University
Ignacio Lizasoain
Ignacio Lizasoain Complutense University of Madrid
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center
Juan C. Leza
Juan C. Leza Complutense University of Madrid
Laszlo Nagy
Laszlo Nagy University of Debrecen
Genhong Cheng
Genhong Cheng University of California, Los Angeles

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