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Neuroscience

D-Index
71
Citations
15095
World Ranking
2449
National Ranking
34

Overview

Juan C. Leza is affiliated with the Complutense University of Madrid in Spain. Their research spans neuroscience, medicine, and psychology, with a focus on multiple subfields such as biological psychiatry, clinical psychology, social psychology, neurology, and molecular biology.

Their work extensively covers key topics including tryptophan and brain disorders, stress responses and cortisol, neuroendocrine regulation and behavior, neuroinflammation and neurodegeneration mechanisms, gut microbiota and health, schizophrenia research and treatment, and bipolar disorder and treatment.

Juan C. Leza has contributed to numerous publications across several scientific venues. Frequent journals for their work include:

  • Neuroscience Applied
  • European Neuropsychopharmacology
  • International Journal of Molecular Sciences
  • Journal of Psychiatric Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent notable papers authored or co-authored by Juan C. Leza are:

  • The Role of the Oral Microbiota Related to Periodontal Diseases in Anxiety, Mood and Trauma- and Stress-Related Disorders, 2022, Frontiers in Psychiatry
  • Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder, 2021, Translational Psychiatry
  • Severe mental illness and European COVID-19 vaccination strategies, 2021, The Lancet Psychiatry
  • Preclinical animal models of mental illnesses to translate findings from the bench to the bedside: Molecular brain mechanisms and peripheral biomarkers associated to early life stress or immune challenges, 2022, European Neuropsychopharmacology
  • Periodontal diseases and depression: A pre-clinical in vivo study, 2021, Journal Of Clinical Periodontology

Collaborations form an important part of Juan C. Leza's research. Frequent co-authors include:

  • Karina S. MacDowell
  • Borja García-Bueno
  • Javier R. Caso
  • Marina Díaz-Marsá
  • David Martín-Hernández

Best Publications

  • Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain.

    José L.M Madrigal;Raquel Olivenza;Marı́a A Moro;Ignacio Lizasoain

  • Role of nitric oxide after brain ischaemia.

    M.A Moro;A Cárdenas;O Hurtado;J.C Leza

  • Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical review

    Helena Palma-Gudiel;Aldo Córdova-Palomera;Juan Carlos Leza;Lourdes Fañanás

  • Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms.

    Borja García-Bueno;Javier R. Caso;Juan C. Leza

  • Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex.

    Raquel Olivenza;María A. Moro;Ignacio Lizasoain;Pedro Lorenzo

  • Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport.

    Olivia Hurtado;María A. Moro;Antonio Cárdenas;Verónica Sánchez

  • Stress-induced neuroinflammation: mechanisms and new pharmacological targets

    C D Munhoz;B García-Bueno;J L M Madrigal;L B Lepsch

  • The Increase in TNF-α Levels Is Implicated in NF-κB Activation and Inducible Nitric Oxide Synthase Expression in Brain Cortex after Immobilization Stress

    José L M Madrigal;Olivia Hurtado;María A Moro;Ignacio Lizasoain

  • Oxidative Stress and Inflammation in First-Episode Psychosis: A Systematic Review and Meta-analysis.

    David Fraguas;David Fraguas;Covadonga M Díaz-Caneja;Covadonga M Díaz-Caneja;Miriam Ayora;Miriam Ayora;Fabián Hernández-Álvarez

  • Toll-Like Receptor 4 Is Involved in Subacute Stress–Induced Neuroinflammation and in the Worsening of Experimental Stroke

    Javier R. Caso;Jesus M. Pradillo;Olivia Hurtado;Juan C. Leza

  • CCL2/MCP-1 modulation of microglial activation and proliferation

    Ara E Hinojosa;Borja Garcia-Bueno;Juan C Leza;Jose L M Madrigal

  • Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms.

    José L. M. Madrigal;María A. Moro;Ignacio Lizasoain;Pedro Lorenzo

  • Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway.

    Iciar Gárate;Borja Garcia-Bueno;Jose Luis Muñoz Madrigal;Javier Rubén Caso

  • Inflammation in schizophrenia: A question of balance.

    Juan C. Leza;Borja García-Bueno;Miquel Bioque;Celso Arango

  • Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

    Iciar Gárate;Borja García-Bueno;José L M Madrigal;Lidia Bravo

  • Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of Psychosis: Toward an Integrative Inflammatory Hypothesis of Schizophrenia

    Borja García-Bueno;Miquel Bioque;Karina S. Mac-Dowell;M. Fe Barcones

  • Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain

    José L M Madrigal;María A Moro;Ignacio Lizasoain;Pedro Lorenzo

  • The Effects of Physical and Psychological Stress on the Gastrointestinal Tract: Lessons from Animal Models

    Javier R. Caso;Juan C. Leza;Luis Menchen

  • In Vitro Ischemic Tolerance Involves Upregulation of Glutamate Transport Partly Mediated by the TACE/ADAM17-Tumor Necrosis Factor-α Pathway

    Cristina Romera;Olivia Hurtado;Sofia H. Botella;Ignacio Lizasoain

  • Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices

    M.A. Moro;J. De Alba;J.C. Leza;P. Lorenzo

  • Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions.

    Alejandra Vargas-Caraveo;Alejandra Vargas-Caraveo;Aline Sayd;Sandra R. Maus;Javier R. Caso

  • Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat.

    L.O. Uttenthal;D. Alonso;A.P. Fernández;R.O. Campbell

  • Astrocyte-Derived MCP-1 Mediates Neuroprotective Effects of Noradrenaline

    Jose L M Madrigal;Juan C Leza;Paul Polak;Sergey Kalinin

Frequent Co-Authors

Ignacio Lizasoain
Ignacio Lizasoain Complutense University of Madrid
María A. Moro
María A. Moro Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.): Madrid, ES
Ana González-Pinto
Ana González-Pinto University of the Basque Country
Celso Arango
Celso Arango Complutense University of Madrid
Esther Berrocoso
Esther Berrocoso University of Cádiz
Miguel Bernardo
Miguel Bernardo University of Barcelona
Julio Bobes
Julio Bobes University of Oviedo
J. Javier Meana
J. Javier Meana University of the Basque Country
Lourdes Fañanás
Lourdes Fañanás University of Barcelona
Josefina Castro-Fornieles
Josefina Castro-Fornieles University of Barcelona

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