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Neuroscience

D-Index
55
Citations
9124
World Ranking
4787
National Ranking
72

Overview

J. Javier Meana is affiliated with the University of the Basque Country in Spain. Their research primarily spans neuroscience and biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, cellular and molecular neuroscience, biological psychiatry, clinical psychology, and neurology.

The scientist has authored numerous papers focusing on various aspects of brain function and neuropharmacology, including serotonin receptor involvement, receptor mechanisms, and the influence of neurotransmitters on behavior. Key recent publications include the following:

  • Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response (2022) in Biomedicine & Pharmacotherapy
  • Adrenergic Modulation With Photochromic Ligands (2020) in Angewandte Chemie International Edition
  • Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex (2020) in European Neuropsychopharmacology
  • Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia (2020) in Frontiers in Pharmacology
  • The Role of α-Synuclein in the Regulation of Serotonin System: Physiological and Pathological Features (2023) in Biomedicines

Their frequent coauthors highlight ongoing collaborative relationships, including researchers such as Luís F. Callado, Igor Horrillo, Rebeca Díez-Alarcia, Jorge E. Ortega, and Itziar Muneta-Arrate.

Meana has published extensively in several scientific journals. The most frequent venues for their work include:

  • European Neuropsychopharmacology
  • Neuroscience Applied
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pharmacological Reports
  • Translational Psychiatry

Their research topics cover a range of areas in neuroscience and molecular biology, focusing on:

  • Tryptophan and brain disorders
  • Neurotransmitter receptor influence on behavior
  • Receptor mechanisms and signaling
  • Psychedelics and drug studies
  • Neuroscience and neuropharmacology research
  • Neuropeptides and animal physiology
  • Epigenetics and DNA methylation

Best Publications

  • Identification of a serotonin/glutamate receptor complex implicated in psychosis

    Javier González-Maeso;Rosalind L. Ang;Tony Yuen;Pokman Chan

  • HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

    Mitsumasa Kurita;Terrell Holloway;Aintzane García-Bea;Aintzane García-Bea;Alexey Kozlenkov

  • Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review.

    P. Molero;J. A. Ramos-Quiroga;R. Martin-Santos;E. Calvo-Sánchez

  • α2-Adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression

    J. Javier Meana;Fernando Barturen;Jesús A. Garcia-Sevilla

  • On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis.

    M Herrera-Marschitz;Z-B You;M Goiny;J J Meana

  • Chronic pain leads to concomitant noradrenergic impairment and mood disorders.

    Cristina Alba-Delgado;Cristina Alba-Delgado;Meritxell Llorca-Torralba;Igor Horrillo;Igor Horrillo;Jorge E. Ortega;Jorge E. Ortega

  • Selective Increase of α2A‐Adrenoceptor Agonist Binding Sites in Brains of Depressed Suicide Victims

    Luis F. Callado;J. Javier Meana;Bernardo Grijalba;Angel Pazos

  • Increased density of mu-opioid receptors in the postmortem brain of suicide victims.

    Ane M. Gabilondo;J. Javier Meana;Jesús A. García-Sevilla;Jesús A. García-Sevilla

  • Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment

    Leyre Urigüen;M. Julia García-Fuster;M. Julia García-Fuster;Luis F. Callado;Benito Morentin

  • Somatodendritic α2-Adrenoceptors in the Locus Coeruleus Are Involved in the In Vivo Modulation of Cortical Noradrenaline Release by the Antidepressant Desipramine

    Yolanda Mateo;Joseba Pineda;J. Javier Meana

  • Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus.

    Eva Martisova;Maite Solas;Igor Horrillo;Jorge E. Ortega

  • Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function

    José L. Moreno;Carolina Muguruza;Adrienne Umali;Steven Mortillo

  • Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia

    José L. Moreno;José L. Moreno;Patricia Miranda-Azpiazu;Aintzane García-Bea;Aintzane García-Bea;Jason Younkin

  • Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of α2A-adrenoceptors

    J González-Maeso;R Rodríguez-Puertas;J J Meana;J J Meana;J A García-Sevilla

  • Increased alpha 2-adrenoceptor density in the frontal cortex of depressed suicide victims.

    J. J. Meana;J. A. García-Sevilla

  • Autoradiographic Demonstration of Increased α2‐Adrenoceptor Agonist Binding Sites in the Hippocampus and Frontal Cortex of Depressed Suicide Victims

    Antonio M. González;Julio Pascual;J. Javier Meana;Fernando Barturen

  • Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response.

    Unknown

  • Distribution of prolyl endopeptidase activities in rat and human brain.

    Jon Irazusta;Gorka Larrinaga;Javier González-Maeso;Javier Gil

  • Dysregulated 5-HT2A receptor binding in postmortem frontal cortex of schizophrenic subjects

    Carolina Muguruza;José L. Moreno;Adrienne Umali;Luis F. Callado

  • Characterization of receptor-mediated [35S]GTPγS binding to cortical membranes from postmortem human brain

    Javier González-Maeso;Rafael Rodrı́guez-Puertas;Ane M Gabilondo;J.Javier Meana

  • Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects.

    Daisuke Ibi;Daisuke Ibi;Daisuke Ibi;Mario de la Fuente Revenga;Nebojsa Kezunovic;Carolina Muguruza

  • mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts.

    Ane M. Gabilondo;J. Javier Meana;Fernando Barturen;Magdalena Sastre

Frequent Co-Authors

Javier González-Maeso
Javier González-Maeso Virginia Commonwealth University
Angel Pazos
Angel Pazos University of Cantabria
Michel Goiny
Michel Goiny Karolinska Institute
Juan C. Leza
Juan C. Leza Complutense University of Madrid
Esther Berrocoso
Esther Berrocoso University of Cádiz
Ernst Brodin
Ernst Brodin Karolinska Institute
Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Lars Terenius
Lars Terenius Karolinska Institute
Bruno Giros
Bruno Giros McGill University
Ana González-Pinto
Ana González-Pinto University of the Basque Country

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