2023 - Research.com Biology and Biochemistry in France Leader Award
Jean-Philippe Pin spends much of his time researching Metabotropic glutamate receptor, G protein-coupled receptor, Receptor, Biochemistry and Metabotropic glutamate receptor 1. His Metabotropic glutamate receptor research focuses on Metabotropic receptor and how it connects with Binding domain. The study incorporates disciplines such as Protein subunit, Inverse agonist, G protein, Protein structure and Computational biology in addition to G protein-coupled receptor.
His biological study spans a wide range of topics, including Signal transduction and Stereochemistry. His research in Biochemistry tackles topics such as Biophysics which are related to areas like Förster resonance energy transfer. His study in Metabotropic glutamate receptor 7 is interdisciplinary in nature, drawing from both Metabotropic glutamate receptor 4, Neuroscience, Long-term depression and Metabotropic glutamate receptor 2.
His primary areas of investigation include Receptor, Metabotropic glutamate receptor, G protein-coupled receptor, Biochemistry and Cell biology. His work in Receptor addresses subjects such as Biophysics, which are connected to disciplines such as Transmembrane domain and HEK 293 cells. As part of one scientific family, Jean-Philippe Pin deals mainly with the area of Metabotropic glutamate receptor, narrowing it down to issues related to the Stereochemistry, and often Glutamic acid and Binding site.
His work carried out in the field of G protein-coupled receptor brings together such families of science as Heterotrimeric G protein, G protein, Computational biology and Förster resonance energy transfer. His Cell biology research incorporates elements of Enzyme-linked receptor and Immune receptor. His study looks at the relationship between Metabotropic glutamate receptor 1 and topics such as Metabotropic glutamate receptor 7, which overlap with Metabotropic glutamate receptor 3.
His main research concerns Receptor, G protein-coupled receptor, Metabotropic glutamate receptor, Allosteric regulation and Biophysics. His Receptor research incorporates themes from Signal transduction, Cell biology and Förster resonance energy transfer. His research integrates issues of Glutamate receptor, Oligomer, HEK 293 cells, G protein and Computational biology in his study of G protein-coupled receptor.
Biochemistry and Agonist are the main topics of his Metabotropic glutamate receptor study. His Biophysics study deals with Transmembrane domain intersecting with Transmembrane protein. As a part of the same scientific family, Jean-Philippe Pin mostly works in the field of Metabotropic glutamate receptor 5, focusing on Metabotropic glutamate receptor 1 and, on occasion, Metabotropic glutamate receptor 7.
Jean-Philippe Pin mainly investigates Receptor, G protein-coupled receptor, Metabotropic glutamate receptor, Allosteric regulation and Cell biology. His Receptor research is multidisciplinary, relying on both Signal transduction, Fluorescent tag and Förster resonance energy transfer. Jean-Philippe Pin has included themes like HEK 293 cells, Protein structure, Ligand binding assay and Computational biology in his G protein-coupled receptor study.
Jean-Philippe Pin studied Metabotropic glutamate receptor and Neuroscience that intersect with Psychopharmacology. His studies deal with areas such as Agonist, Intrinsic activity, Metabotropic receptor and Biophysics as well as Allosteric regulation. His work in Metabotropic glutamate receptor 2 tackles topics such as Metabotropic glutamate receptor 1 which are related to areas like Metabotropic glutamate receptor 6 and Metabotropic glutamate receptor 7.
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Pharmacology and functions of metabotropic glutamate receptors.
Conn Pj;Pin Jp.
Annual Review of Pharmacology and Toxicology (1997)
The metabotropic glutamate receptors: structure and functions.
J.-P. Pin;R. Duvoisin.
Molecular tinkering of G protein‐coupled receptors: an evolutionary success
Joël Bockaert;Jean Philippe Pin.
The EMBO Journal (1999)
Glutamate stimulates inositol phosphate formation in striatal neurones
Fritz Sladeczek;Jean-Philippe Pin;Max Récasens;Joël Bockaert.
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin;Thierry Galvez;Laurent Prézeau.
Pharmacology & Therapeutics (2003)
NMDA receptors activate the arachidonic acid cascade system in striatal neurons
A. Dumuis;M. Sebben;L. Haynes;J. P. Pin.
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4.
Nicolas Triballeau;Francine Acher;Isabelle Brabet;Jean-Philippe Pin.
Journal of Medicinal Chemistry (2005)
Metabotropic glutamate receptors: From the workbench to the bedside
F Nicoletti;J Bockaert;Graham L Collingridge;PJ Conn.
G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives
Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola.
Pharmacological Reviews (2014)
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.
Damien Maurel;Laëtitia Comps-Agrar;Laëtitia Comps-Agrar;Carsten Brock;Carsten Brock;Marie-Laure Rives;Marie-Laure Rives.
Nature Methods (2008)
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