Jean-Philippe Pin

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Best Publications

• The metabotropic glutamate receptors: structure and functions.

  J.-P. Pin;R. Duvoisin

  3647
  Citations

• Pharmacology and functions of metabotropic glutamate receptors.

  Unknown

  3251
  Citations

• Molecular tinkering of G protein‐coupled receptors: an evolutionary success

  Joël Bockaert;Jean Philippe Pin

  2072
  Citations

• Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.

  Jean-Philippe Pin;Thierry Galvez;Laurent Prézeau

  958
  Citations

• Glutamate stimulates inositol phosphate formation in striatal neurones

  Fritz Sladeczek;Jean-Philippe Pin;Max Récasens;Joël Bockaert

  930
  Citations

• International Union of Pharmacology. XLVI. G Protein-Coupled Receptor List

  Steven M. Foord;Tom I. Bonner;Richard R. Neubig;Edward M. Rosser

  791
  Citations

• NMDA receptors activate the arachidonic acid cascade system in striatal neurons

  A. Dumuis;M. Sebben;L. Haynes;J. P. Pin

  764
  Citations

• Metabotropic glutamate receptors: From the workbench to the bedside

  F Nicoletti;J Bockaert;Graham L Collingridge;PJ Conn

  741
  Citations

• Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4.

  Unknown

  620
  Citations

• G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

  Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola

  607
  Citations

• Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.

  Damien Maurel;Laëtitia Comps-Agrar;Laëtitia Comps-Agrar;Carsten Brock;Carsten Brock;Marie-Laure Rives;Marie-Laure Rives

  583
  Citations

• Generic GPCR residue numbers – aligning topology maps while minding the gaps

  Vignir Isberg;Chris de Graaf;Andrea Bortolato;Vadim Cherezov

  518
  Citations

• Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

  F. Ango;L. Prézeau;T. Muller;J. C. Tu

  488
  Citations

• CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.

  Stephane Litschig;Fabrizio Gasparini;Doris Rueegg;Natacha Stoehr

  488
  Citations

• Building a new conceptual framework for receptor heteromers

  Sergi Ferré;Ruben Baler;Michel Bouvier;Marc G. Caron

  479
  Citations

• Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function

  Thierry Galvez;Béatrice Duthey;Julie Kniazeff;Jaroslav Blahos

  464
  Citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

  Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  427
  Citations

• Closed state of both binding domains of homodimeric mGlu receptors is required for full activity

  Julie Kniazeff;Anne-Sophie Bessis;Damien Maurel;Hervé Ansanay

  415
  Citations

• The metabotropic glutamate receptors: structure, activation mechanism and pharmacology.

  Jean-Philippe Pin;Francine Acher

  405
  Citations

• Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

  Laura Albizu;Martin Cottet;Martin Cottet;Martin Cottet;Michaela Kralikova;Stoytcho Stoev

  394
  Citations

• The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors

  Adriana Pagano;Adriana Pagano;Doris Rüegg;Stephane Litschig;Natacha Stoehr

  393
  Citations

• Molecular determinants of metabotropic glutamate receptor signaling.

  Antonio De Blasi;Peter Jeffrey Conn;Jean Philippe Pin;Ferdinando Nicoletti

  372
  Citations