World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
98
Citations
34088
World Ranking
1400
National Ranking
540

Biology and Biochemistry

D-Index
105
Citations
39375
World Ranking
1201
National Ranking
712

Overview

P. Jeffrey Conn is affiliated with Vanderbilt University in the United States. Their research primarily addresses key areas within neuroscience and biochemistry, genetics, and molecular biology.

The scientist's main fields of study include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their subfields of study are:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Genetics
  • Neurology

The primary topics covered in their publications focus on:

  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Memory and Neural Mechanisms
  • Nicotinic Acetylcholine Receptors Study
  • Neurotransmitter Receptor Influence on Behavior
  • Neural dynamics and brain function
  • Genetics and Neurodevelopmental Disorders

Their recent papers include:

  • "Targeting muscarinic receptors to treat schizophrenia", 2021, Behavioural Brain Research
  • "Metabotropic Glutamate Receptors As Emerging Targets for the Treatment of Schizophrenia", 2022, Molecular Pharmacology
  • "Targeting metabotropic glutamate receptors for the treatment of depression and other stress-related disorders", 2021, Neuropharmacology
  • "D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning", 2023, Neuron
  • "Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking", 2020, Neuropharmacology

Frequent coauthors in their work are:

  • Craig W. Lindsley
  • Colleen M. Niswender
  • Alice L. Rodriguez
  • Sichen Chang
  • Olivier Boutaud

The venues where P. Jeffrey Conn most often publishes their work include:

  • Bioorganic & Medicinal Chemistry Letters
  • ACS Chemical Neuroscience
  • ACS Medicinal Chemistry Letters
  • Biological Psychiatry
  • Journal of Pharmacology and Experimental Therapeutics

Best Publications

  • Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

    Colleen M. Niswender;P. Jeffrey Conn

  • Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

    P. Jeffrey Conn;Arthur Christopoulos;Craig W. Lindsley;Craig W. Lindsley

  • Metabotropic glutamate receptors in brain function and pathology

    Darryle D. Schoepp;P.Jeffrey Conn

  • Metabotropic glutamate receptors: From the workbench to the bedside

    F Nicoletti;J Bockaert;Graham L Collingridge;PJ Conn

  • Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

    Huixian Wu;Chong Wang;Karen J. Gregory;Karen J. Gregory;Gye Won Han

  • Metabotropic Glutamate Receptors 1 and 5 Differentially Regulate CA1 Pyramidal Cell Function

    G Mannaioni;M J Marino;O Valenti;O Valenti;S F Traynelis

  • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

    Hazar Awad;George W. Hubert;Yoland Smith;Allan I. Levey

  • Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

    P. Jeffrey Conn;Craig W. Lindsley;Craig W. Lindsley;Carrie K. Jones

  • Metabotropic glutamate receptors in the basal ganglia motor circuit

    P. Jeffrey Conn;Giuseppe Battaglia;Michael J. Marino;Ferdinando Nicoletti

  • A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models

    Gene G. Kinney;Julie A. O'Brien;Wei Lemaire;Maryann Burno

  • N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-d-aspartate receptor activity

    Cyrille Sur;Pierre J. Mallorga;Marion Wittmann;Marlene A. Jacobson

  • Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

    Unknown

  • Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-d-aspartate (NMDA) receptor currents in hippocampal pyramidal cells

    M J Marino;S T Rouse;A I Levey;L T Potter

  • A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.

    J. K. Shirey;A. E. Brady;P. J. Jones;A. A. Davis

  • Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

    P. Jeffrey Conn;Carrie K. Jones;Craig W. Lindsley;Craig W. Lindsley

  • Glutamate receptors as therapeutic targets for Parkinson's disease.

    Kari A. Johnson;P. Jeffrey Conn;Colleen M. Niswender

  • Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment.

    Michael J. Marino;David L. Williams;Julie A. O'Brien;Ornella Valenti

  • Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders

    P. Jeffrey Conn;Craig W. Lindsley;Jens Meiler;Colleen M. Niswender

  • Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats

    Carrie K. Jones;Ashley E. Brady;Albert A. Davis;Zixiu Xiang

  • A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity.

    Ruggero Galici;Nicholas G. Echemendia;Alice L. Rodriguez;P. Jeffrey Conn

  • A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.

    Julie A. O'Brien;Wei Lemaire;Tsing-Bau Chen;Raymond S. L. Chang

Frequent Co-Authors

Craig W. Lindsley
Craig W. Lindsley Vanderbilt University
Colleen M. Niswender
Colleen M. Niswender Vanderbilt University
Carrie K. Jones
Carrie K. Jones Vanderbilt University
Shaun R. Stauffer
Shaun R. Stauffer Cleveland Clinic
C. David Weaver
C. David Weaver Vanderbilt University
Michael Bubser
Michael Bubser Vanderbilt University
Danny G. Winder
Danny G. Winder Vanderbilt University
Yoland Smith
Yoland Smith Emory University
Jens Meiler
Jens Meiler Vanderbilt University
Richard A Williams
Richard A Williams Heriot-Watt University

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