2018 - Fellow, National Academy of Inventors
2016 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary areas of study are Allosteric regulation, Pharmacology, Stereochemistry, Neuroscience and Allosteric modulator. His work carried out in the field of Allosteric regulation brings together such families of science as Muscarinic acetylcholine receptor, G protein-coupled receptor and Metabotropic glutamate receptor. His studies in G protein-coupled receptor integrate themes in fields like Allosteric enzyme, Computational biology and Drug discovery.
His research in Pharmacology tackles topics such as Metabotropic glutamate receptor 4 which are related to areas like Metabotropic glutamate receptor 7. His Stereochemistry research is multidisciplinary, relying on both Selectivity, Structure–activity relationship, Chemical synthesis and Antagonist. His work deals with themes such as Long-term potentiation, Schizophrenia and Long-Term Synaptic Depression, which intersect with Neuroscience.
Craig W. Lindsley mainly focuses on Allosteric regulation, Pharmacology, Stereochemistry, Neuroscience and Allosteric modulator. Craig W. Lindsley has included themes like Glutamate receptor, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor and Muscarinic acetylcholine receptor in his Allosteric regulation study. Craig W. Lindsley focuses mostly in the field of Metabotropic glutamate receptor 5, narrowing it down to matters related to Metabotropic glutamate receptor 2 and, in some cases, Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 3.
His work in Pharmacology tackles topics such as In vivo which are related to areas like In vitro. His Stereochemistry research includes elements of Selectivity, Structure–activity relationship, Chemical synthesis and Drug discovery. In most of his Neuroscience studies, his work intersects topics such as Long-term potentiation.
The scientist’s investigation covers issues in Racism, Publishing, Inclusion, Commit and Workforce. Viewpoints, Diversity, Solidarity and Public relations are fields of study that overlap with his Publishing research.
Craig W. Lindsley focuses on Allosteric regulation, Neuroscience, Allosteric modulator, Pharmacology and Muscarinic acetylcholine receptor. His Allosteric regulation research incorporates elements of In vivo, Stereochemistry, Carboxamide and Metabotropic glutamate receptor. His research in Neuroscience intersects with topics in Synaptic plasticity, Postsynaptic potential and Metabotropic receptor.
His Allosteric modulator research integrates issues from Computational biology, Cooperativity, Metabotropic glutamate receptor 7 and Drug discovery. His research integrates issues of Hyperpolarization, Membrane potential, Kir6.2, Ion channel and Hyperinsulinism in his study of Pharmacology. The Muscarinic acetylcholine receptor study combines topics in areas such as Electrophysiology, Cholinergic, Agonist, Self-administration and Dopamine.
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Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn;Arthur Christopoulos;Craig W. Lindsley;Craig W. Lindsley.
Nature Reviews Drug Discovery (2009)
Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.
Craig W. Lindsley;Zhijian Zhao;William H. Leister;Ronald G. Robinson.
Bioorganic & Medicinal Chemistry Letters (2005)
The Akt/PKB pathway : molecular target for cancer drug discovery
Jin Q Cheng;Craig W Lindsley;George Z Cheng;Hua Yang.
Efficient synthesis of imidazoles from aldehydes and 1,2-diketones using microwave irradiation.
Scott E. Wolkenberg;David D. Wisnoski;William H. Leister;Yi Wang.
Organic Letters (2004)
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
P. Jeffrey Conn;Craig W. Lindsley;Craig W. Lindsley;Carrie K. Jones.
Trends in Pharmacological Sciences (2009)
In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.
Jijun Hao;Joshua N. Ho;Jana A. Lewis;Kaleh A. Karim.
ACS Chemical Biology (2010)
A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models
Gene G. Kinney;Julie A. O'Brien;Wei Lemaire;Maryann Burno.
Journal of Pharmacology and Experimental Therapeutics (2005)
Phospholipase D - enzymology, functionality, and chemical modulation
Paige E. Selvy;Robert R. Lavieri;Craig W. Lindsley;H. Alex Brown.
Chemical Reviews (2011)
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation
Lei Ma;Matthew A. Seager;Marion Wittmann;Marlene Jacobson.
Proceedings of the National Academy of Sciences of the United States of America (2009)
General microwave-assisted protocols for the expedient synthesis of quinoxalines and heterocyclic pyrazines
Zhijian Zhao;David D Wisnoski;Scott E Wolkenberg;William H Leister.
Tetrahedron Letters (2004)
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