World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
91
Citations
32369
World Ranking
1954
National Ranking
716

Biology and Biochemistry

D-Index
95
Citations
35175
World Ranking
1889
National Ranking
1039

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Craig W. Lindsley is affiliated with Vanderbilt University in the United States. Their research spans multiple disciplines, primarily focusing on molecular biology, cellular and molecular neuroscience, history and philosophy of science, organic chemistry, and pharmacology.

The scientist's work includes contributions in the following main topics:

  • Academic Writing and Publishing
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Nicotinic Acetylcholine Receptors Study
  • Computational Drug Discovery Methods
  • Neurotransmitter Receptor Influence on Behavior
  • Ion Channel Regulation and Function

Frequent collaborators associated with this research include Dennis C. Liotta, Courtney C. Aldrich, Gunda I. Georg, Shaomeng Wang, and Cynthia J. Burrows.

The scientist has published extensively in several prominent venues, including:

  • ACS Chemical Neuroscience
  • Journal of Medicinal Chemistry
  • ACS Medicinal Chemistry Letters
  • Bioorganic & Medicinal Chemistry Letters
  • ACS Pharmacology & Translational Science

Key recent publications include:

  • "Classics in Chemical Neuroscience: Baclofen," 2020, ACS Chemical Neuroscience
  • "Rational Molecular Editing: A New Paradigm in Drug Discovery," 2024, Journal of Medicinal Chemistry
  • "Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons," 2022, Neuron
  • "Molecular Skeleton Editing for New Drug Discovery," 2024, Journal of Medicinal Chemistry
  • "Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents," 2020, Biological Psychiatry

Craig W. Lindsley's contributions have been recognized by their election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2016 and as a Fellow of the National Academy of Inventors in 2018.

Best Publications

  • Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

    P. Jeffrey Conn;Arthur Christopoulos;Craig W. Lindsley;Craig W. Lindsley

  • Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

    Craig W. Lindsley;Zhijian Zhao;William H. Leister;Ronald G. Robinson

  • The Akt/PKB pathway : molecular target for cancer drug discovery

    Jin Q Cheng;Craig W Lindsley;George Z Cheng;Hua Yang

  • Efficient synthesis of imidazoles from aldehydes and 1,2-diketones using microwave irradiation.

    Scott E. Wolkenberg;David D. Wisnoski;William H. Leister;Yi Wang

  • In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.

    Jijun Hao;Joshua N. Ho;Jana A. Lewis;Kaleh A. Karim

  • Phospholipase D - enzymology, functionality, and chemical modulation

    Paige E. Selvy;Robert R. Lavieri;Craig W. Lindsley;H. Alex Brown

  • Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

    P. Jeffrey Conn;Craig W. Lindsley;Craig W. Lindsley;Carrie K. Jones

  • The Ecstasy and Agony of Assay Interference Compounds

    Courtney Aldrich;Carolyn Bertozzi;Gunda I. Georg;Laura Kiessling

  • A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models

    Gene G. Kinney;Julie A. O'Brien;Wei Lemaire;Maryann Burno

  • Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation

    Lei Ma;Matthew A. Seager;Marion Wittmann;Marlene Jacobson

  • A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.

    J. K. Shirey;A. E. Brady;P. J. Jones;A. A. Davis

  • General microwave-assisted protocols for the expedient synthesis of quinoxalines and heterocyclic pyrazines

    Zhijian Zhao;David D Wisnoski;Scott E Wolkenberg;William H Leister

  • Phospholipase D Signaling Pathways and Phosphatidic Acid as Therapeutic Targets in Cancer

    Ronald C. Bruntz;Craig W. Lindsley;H. Alex Brown

  • Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

    P. Jeffrey Conn;Carrie K. Jones;Craig W. Lindsley;Craig W. Lindsley

  • Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

    Sarah A Scott;Paige E Selvy;Jason R Buck;Hyekyung P Cho

  • Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders

    P. Jeffrey Conn;Craig W. Lindsley;Jens Meiler;Colleen M. Niswender

  • Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats

    Carrie K. Jones;Ashley E. Brady;Albert A. Davis;Zixiu Xiang

  • Drugs for Allosteric Sites on Receptors

    Cody J. Wenthur;Patrick R. Gentry;Thomas P. Mathews;Craig W. Lindsley

  • A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.

    Julie A. O'Brien;Wei Lemaire;Tsing-Bau Chen;Raymond S. L. Chang

  • M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

    Weixing Shen;Joshua L. Plotkin;Veronica Francardo;Wai Kin D. Ko;Wai Kin D. Ko

  • Application of combinatorial chemistry science on modern drug discovery.

    J. Phillip Kennedy;Lyndsey Williams;Thomas M. Bridges;R. Nathan Daniels

Frequent Co-Authors

P. Jeffrey Conn
P. Jeffrey Conn Vanderbilt University
Colleen M. Niswender
Colleen M. Niswender Vanderbilt University
Carrie K. Jones
Carrie K. Jones Vanderbilt University
Shaun R. Stauffer
Shaun R. Stauffer Cleveland Clinic
Dennis C. Liotta
Dennis C. Liotta Emory University
Gunda I. Georg
Gunda I. Georg University of Minnesota
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Alanna Schepartz
Alanna Schepartz University of California, Berkeley
Kenneth M. Merz
Kenneth M. Merz Michigan State University

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