What is he best known for?
The fields of study he is best known for:
Michael A. Frohman mainly focuses on Cell biology, Phospholipase D, PLD2, Phosphatidic acid and Biochemistry.
Michael A. Frohman interconnects Phospholipase and Lipid signaling in the investigation of issues within Cell biology.
A large part of his Phospholipase D studies is devoted to Phospholipase D1.
His work carried out in the field of PLD2 brings together such families of science as Phosphatidylinositol, Protein kinase A and Second messenger system.
His studies in Phosphatidic acid integrate themes in fields like Vesicle, Chemotaxis, Brefeldin A and Pleckstrin homology domain.
His Biochemistry research integrates issues from Dentate gyrus and Mossy fiber.
His most cited work include:
- Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer (4311 citations)
- REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons (926 citations)
- Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation (727 citations)
What are the main themes of his work throughout his whole career to date?
Michael A. Frohman mainly investigates Cell biology, Phospholipase D, Biochemistry, PLD2 and Phosphatidic acid.
His Cell biology study incorporates themes from Cell and Vesicle.
Michael A. Frohman studies Phospholipase D, namely Phospholipase D1.
His studies deal with areas such as Protein kinase A, Cancer cell, ADP ribosylation factor, MAPK/ERK pathway and Gene isoform as well as PLD2.
His research on Phosphatidic acid also deals with topics like
- Second messenger system that connect with fields like Lipid signaling,
- Diacylglycerol kinase and related Lysophosphatidic acid.
The study incorporates disciplines such as Complementary DNA, Genetics and Gene in addition to Molecular biology.
He most often published in these fields:
- Cell biology (57.47%)
- Phospholipase D (53.45%)
- Biochemistry (28.16%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (57.47%)
- Phospholipase D (53.45%)
- Phosphatidic acid (24.71%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Phospholipase D, Phosphatidic acid, Phospholipase D1 and PLD2.
His Cell biology research is multidisciplinary, relying on both Phospholipase, Molecular biology, Cardiolipin and Membrane lipids.
His Phospholipase D study contributes to a more complete understanding of Signal transduction.
His biological study spans a wide range of topics, including Knockout mouse, Lipid signaling and Second messenger system.
His work investigates the relationship between Phospholipase D1 and topics such as Tumor microenvironment that intersect with problems in Metastasis.
Michael A. Frohman has included themes like Cancer research, Cancer cell, Toxicity, Alzheimer's disease and Isozyme in his PLD2 study.
Between 2013 and 2021, his most popular works were:
- The phospholipase D superfamily as therapeutic targets. (115 citations)
- Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division (91 citations)
- Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2 (91 citations)
In his most recent research, the most cited papers focused on:
Mitochondrion, Cell biology, Phospholipase D, Phosphatidic acid and Cardiolipin are his primary areas of study.
His work on Cytochrome c oxidase and Cytochrome c as part of his general Mitochondrion study is frequently connected to Glomerulosclerosis and Kidney metabolism, thereby bridging the divide between different branches of science.
The various areas that Michael A. Frohman examines in his Cell biology study include Phospholipase and Membrane, Phospholipid.
Phospholipase D is a subfield of Enzyme that he tackles.
His study in Phosphatidic acid is interdisciplinary in nature, drawing from both Lipid signaling, Phenotype, RNA interference, Knockout mouse and Signal transduction.
Michael A. Frohman has researched Cardiolipin in several fields, including Mitochondrial apoptosis-induced channel, ATP–ADP translocase and Inner mitochondrial membrane.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
