World's Best Scientists 2026 revealed!

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Molecular Biology

D-Index
66
Citations
13100
World Ranking
1630
National Ranking
823

Overview

David A. Foster is affiliated with City University of New York in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with notable contributions to subfields such as Molecular Biology, Cancer Research, Biotechnology, Oncology, and Plant Science.

The main topics covered in their work include:

  • PI3K/AKT/mTOR signaling in cancer
  • Metabolism, Diabetes, and Cancer
  • Protein Kinase Regulation and GTPase Signaling
  • Cancer, Hypoxia, and Metabolism
  • ATP Synthase and ATPases Research
  • Cancer Research and Treatments
  • Cancer-related Molecular Pathways

Foster's recent papers showcase a focus on cellular and molecular mechanisms related to cancer and metabolism. These publications include:

  • "Regulation of mTOR by phosphatidic acid," 2023, Trends in Endocrinology and Metabolism
  • "Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin," 2021, Cancer Letters
  • "Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells," 2022, PLoS ONE
  • "Albumin promotes the progression of fibroblasts through late G1 into S-phase in the absence of growth factors," 2020, Cell Cycle

Frequent coauthors regularly collaborating with Foster include María A. Frías, Ahmet Hatipoğlu, Deepak Menon, Talia Levy, and Sohag Chakraborty.

Their research has been published across multiple venues, including:

  • Trends in Endocrinology and Metabolism
  • PLoS ONE
  • Cancer Letters
  • Cell Cycle

Best Publications

  • Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

    Debabrata Mukhopadhyay;Leonidas Tsiokas;Xiao Mai Zhou;David Foster

  • Signal transduction through lipid second messengers

    Sarah Spiegel;David Foster;Richard Kolesnick

  • Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation

    Zhimin Lu;David Liu;Armand Hornia;Wayne Devonish

  • Phospholipase D in cell proliferation and cancer.

    David A. Foster;Lizhong Xu

  • Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

    Alfredo Toschi;Evan Lee;Limei Xu;Avalon Garcia

  • Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2

    Alfredo Toschi;Evan Lee;Noga Gadir;Michael Ohh

  • Involvement of Ral GTPase in v-Src-induced phospholipase D activation

    Hong Jiang;Jing-Qing Luo;Takeshi Urano;Paul Frankel

  • Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s).

    David A. Foster;Paige Yellen;Limei Xu;Mahesh Saqcena

  • Tumor promotion by depleting cells of protein kinase C delta.

    Zhimin Lu;Armand Hornia;You Wei Jiang;You Wei Jiang;Qun Zang

  • Regulation of mTOR by Phosphatidic Acid

    David A. Foster

  • Role for phospholipase D in receptor-mediated endocytosis.

    Yingjie Shen;Lizhong Xu;David A. Foster

  • Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.

    L Hui;Y Zheng;Y Yan;J Bargonetti

  • Phospholipase D confers rapamycin resistance in human breast cancer cells

    Yuhong Chen;Yang Zheng;David A Foster

  • Protein Kinase Cδ Mediates Neurogenic but Not Mitogenic Activation of Mitogen-Activated Protein Kinase in Neuronal Cells

    Kevin C. Corbit;David A. Foster;Marsha Rich Rosner

  • Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.

    David A. Foster

  • Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells.

    Xin Chen;Li Hui;David A. Foster;Charles Michael Drain

  • The enigmatic protein kinase Cδ: complex roles in cell proliferation and survival

    Desmond N. Jackson;David A. Foster

  • Phospholipase D couples survival and migration signals in stress response of human cancer cells.

    Yang Zheng;Vanessa Rodrik;Alfredo Toschi;Ming Shi

  • Targeting mTOR with rapamycin: One dose does not fit all

    David A. Foster;Alfredo Toschi

  • An EGF receptor/Ral-GTPase signaling cascade regulates c–Src activity and substrate specificity

    Takanori Goi;Michail Shipitsin;Zhimin Lu;David A. Foster

Frequent Co-Authors

Zhimin Lu
Zhimin Lu Zhejiang University
Larry A. Feig
Larry A. Feig Tufts University
Vikas P. Sukhatme
Vikas P. Sukhatme Emory University
Hong Jiang
Hong Jiang Central South University
Michael Ohh
Michael Ohh University of Toronto
Ulf R. Rapp
Ulf R. Rapp Max Planck Society
Charles Michael Drain
Charles Michael Drain City University of New York
Sangram S. Sisodia
Sangram S. Sisodia University of Chicago
Huaxi Xu
Huaxi Xu Xiamen University
Joan S. Brugge
Joan S. Brugge Harvard University

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