World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
56
Citations
14070
World Ranking
4472
National Ranking
389

Overview

Chao Zhao is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple interconnected fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Zhao's work explores various subfields, including Molecular Biology, Developmental Neuroscience, Pathology and Forensic Medicine, Neurology, and Cancer Research.

The main topics covered in Zhao's research include:

  • Neurogenesis and neuroplasticity mechanisms
  • Gut microbiota and health
  • Multiple Sclerosis Research Studies
  • MicroRNA in disease regulation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Research and Splicing
  • Extracellular vesicles in disease

Zhao has published extensively in a range of scientific journals. The frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Glia, eLife, Research Square (Research Square), and Acta Neuropathologica.

Their recent papers illustrate a focus on neurological and cellular mechanisms, with topics covering neuroprotection, differentiation of oligodendrocytes, and autophagy in disease contexts. Notable recent papers include:

  • Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis, 2020, Acta Neuropathologica
  • Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence, 2021, Cell Reports
  • Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis, 2020, Cell stem cell
  • Activation of Pancreatic Acinar FXR Protects against Pancreatitis via Osgin1-Mediated Restoration of Efficient Autophagy, 2022, Research
  • Myc determines the functional age state of oligodendrocyte progenitor cells, 2021, Nature Aging

Zhao collaborates frequently with a group of coauthors, including Robin J.M. Franklin, David H. Rowitch, Miaomiao Pan, Zhenming Xiao, and Amar Sharma. Cooperation with these researchers has resulted in multiple joint publications, with Robin J.M. Franklin being the most frequent coauthor.

Best Publications

  • Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation.

    Mark R. Kotter;Wen-Wu Li;Chao Zhao;Robin J. M. Franklin

  • CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

    Malgorzata Zawadzka;Malgorzata Zawadzka;Leanne E. Rivers;Stephen P.J. Fancy;Stephen P.J. Fancy;Chao Zhao

  • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

    Stephen P.J. Fancy;Sergio E. Baranzini;Chao Zhao;Dong-In Yuk

  • The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation

    Fraser J. Sim;Chao Zhao;Jacques Penderis;Jacques Penderis;Robin J. M. Franklin

  • Retinoid X receptor gamma signaling accelerates CNS remyelination

    Jeffrey K Huang;Andrew A Jarjour;Brahim Nait Oumesmar;Christophe Kerninon

  • Regulatory T cells promote myelin regeneration in the central nervous system.

    Yvonne Dombrowski;Thomas O'Hagan;Marie Dittmer;Rosana Penalva

  • bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

    Heather A. Arnett;Stephen P. J. Fancy;John A. Alberta;Chao Zhao

  • Niche stiffness underlies the ageing of central nervous system progenitor cells.

    Michael Segel;Björn Neumann;Myfanwy F. E. Hill;Isabell P. Weber

  • Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

    Björn Neumann;Roey Baror;Chao Zhao;Michael Segel

  • Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression

    Mark R. Kotter;Chao Zhao;Nico van Rooijen;Robin J.M. Franklin

  • Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

    Stephen P J Fancy;Emily P Harrington;Tracy J Yuen;John C Silbereis

  • Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS

    Stephen P.J. Fancy;Chao Zhao;Robin J.M. Franklin

  • Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

    S. Y Christin Chong;Sheila S. Rosenberg;Stephen P J Fancy;Chao Zhao

  • Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

    Josephine M. J. Stoffels;Jenny C. de Jonge;Mirjana Stancic;Anita Nomden

  • LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination

    Dingya Sun;Zhongwang Yu;Xue Fang;Mingdong Liu

  • Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.

    E. K. Ainscow;Chao Zhao;G. A. Rutter

  • Overcoming remyelination failure in multiple sclerosis and other myelin disorders.

    Stephen P.J. Fancy;Mark R. Kotter;Emily P. Harrington;Jeffrey K. Huang

  • Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells.

    Anna Setzu;Justin D. Lathia;Justin D. Lathia;Chao Zhao;Karen Wells

  • The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain.

    D.W Hampton;K.E Rhodes;C Zhao;R.J.M Franklin

  • Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination

    Wen-Wu Li;Anna Setzu;Chao Zhao;Robin J.M. Franklin

  • Secretory-granule dynamics visualized in vivo with a phogrin–green fluorescent protein chimaera

    Aristea E. Pouli;Evaggelia Emmanouilidou;Chao Zhao;Christina Wasmeier

  • Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination.

    Emily P. Harrington;Chao Zhao;Stephen P. J. Fancy;Sovann Kaing

  • Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination.

    Chao Zhao;Wen-Wu Li;Robin J.M. Franklin

  • Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis

    Jessica L. Zambonin;Chao Zhao;Nobuhiko Ohno;Graham R. Campbell

Frequent Co-Authors

Stephen P.J. Fancy
Stephen P.J. Fancy University of California, San Francisco
Wia Baron
Wia Baron University Medical Center Groningen
Klaus-Armin Nave
Klaus-Armin Nave Max Planck Society
Ragnhildur Thóra Káradóttir
Ragnhildur Thóra Káradóttir University of Cambridge
Jonah R. Chan
Jonah R. Chan University of California, San Francisco
Sebastien Couillard-Despres
Sebastien Couillard-Despres Paracelsus Medical University
Ludwig Aigner
Ludwig Aigner Paracelsus Medical University
James W. Fawcett
James W. Fawcett University of Cambridge
Markus Kipp
Markus Kipp University of Rostock
Markus M. Heimesaat
Markus M. Heimesaat Charité - University Medicine Berlin

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