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Neuroscience

D-Index
72
Citations
14758
World Ranking
2351
National Ranking
210

Overview

Cordian Beyer is affiliated with RWTH Aachen University in Germany and is active in research areas bridging biochemistry, genetics, molecular biology, medicine, and neuroscience. Their work spans multiple interconnected fields, with a substantial focus on molecular biology and neurology.

Their recent publications illustrate a concentration on neuroinflammation, neurodegeneration, and immune-related mechanisms explored through molecular and cellular pathways. Examples of recent papers include:

  • Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells, 2021, published in Cells
  • Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model, 2022, published in Journal of Neuroinflammation
  • Gonadal Hormones E2 and P Mitigate Cerebral Ischemia-Induced Upregulation of the AIM2 and NLRC4 Inflammasomes in Rats, 2020, published in International Journal of Molecular Sciences
  • Gut microbiota and brain alterations in a translational anorexia nervosa rat model, 2020, published in Journal of Psychiatric Research
  • Presence of The NLRP3 Inflammasome Components in Semen of Varicocele Patients, 2020, published in PubMed

Beyer's research often revolves around the study of inflammasomes and neuroinflammation, microRNA's role in disease regulation, and the influence of gut microbiota on health. This focus aligns with primary topics associated with their work, which include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • MicroRNA in disease regulation
  • Eating Disorders and Behaviors
  • Inflammasome and immune disorders
  • Diet and metabolism studies
  • Circular RNAs in diseases
  • Gut microbiota and health

Their publications have appeared frequently in several scientific journals and venues, reflecting interdisciplinary reach. Prominent publication venues include:

  • Annals of Anatomy - Anatomischer Anzeiger
  • International Journal of Molecular Sciences
  • Molecular Neurobiology
  • Journal of Molecular Neuroscience
  • Adipositas - Ursachen Folgeerkrankungen Therapie

Collaborations constitute an important aspect of their research, featuring frequent coauthors such as:

  • Clara Voelz
  • Adib Zendedel
  • Jochen Seitz
  • Stefanie Trinh
  • Nima Sanadgol

Their expertise extends into specialized subfields including molecular biology, neurology, cancer research, physiology, and clinical psychology. The interplay of these scientific domains supports their comprehensive approach to understanding molecular mechanisms that underpin neurological and metabolic disorders.

Best Publications

  • The cuprizone animal model: new insights into an old story

    Markus Kipp;Tim Clarner;Jon Dang;Sjef Copray

  • NLRP3 Inflammasome Is Expressed by Astrocytes in the SOD1 Mouse Model of ALS and in Human Sporadic ALS Patients

    Sonja Johann;Marius Heitzer;Mithila Kanagaratnam;Anand Goswami

  • IKK mediates ischemia-induced neuronal death.

    Oliver Herrmann;Bernd Baumann;Rossana de Lorenzi;Sajjad Muhammad

  • Inflammasome: its role in traumatic brain and spinal cord injury†

    Keywan Mortezaee;Neda Khanlarkhani;Cordian Beyer;Adib Zendedel

  • Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen

    Justyna Pawlak;Veronica Brito;Eva Küppers;Cordian Beyer

  • 17β‐estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice

    Peter Acs;Markus Kipp;Akvile Norkute;Sonja Johann

  • Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control.

    Unknown

  • Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model

    Adib Zendedel;Adib Zendedel;Sonja Johann;Soraya Mehrabi;Mohammad-taghi Joghataei

  • Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions.

    Tim Clarner;Felix Diederichs;Katharina Berger;Bernd Denecke

  • Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis

    J. Prause;A. Goswami;I. Katona;A. Roos

  • Neuroprotective effects of argon in an in vivo model of transient middle cerebral artery occlusion in rats

    Yu-Mi Ryang;Astrid V. Fahlenkamp;Rolf Rossaint;Dominik Wesp

  • Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: sex differences and effects of sex steroids

    Unknown

  • CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

    Tim Clarner;Katharina Janssen;Lara Nellessen;Martin Stangel

  • Progesterone therapy induces an M1 to M2 switch in microglia phenotype and suppresses NLRP3 inflammasome in a cuprizone-induced demyelination mouse model.

    Roya Aryanpour;Parichehr Pasbakhsh;Kazem Zibara;Zeinab Namjoo

  • Regulation of brain microglia by female gonadal steroids

    Pardes Habib;Cordian Beyer

  • Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores

    Unknown

  • Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats

    Jon Dang;Bhimashankar Mitkari;Markus Kipp;Cordian Beyer

  • Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia.

    Sonja Johann;Cordian Beyer

  • Estrogen receptor-alpha is associated with the plasma membrane of astrocytes and coupled to the MAP/Src-kinase pathway.

    Justyna Pawlak;Magdalena Karolczak;Andre Krust;P. Chambon

  • Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling

    Unknown

  • TTC staining of damaged brain areas after MCA occlusion in the rat does not constrict quantitative gene and protein analyses.

    Martin Kramer;Jon Dang;Fabian Baertling;Bernd Denecke

  • Inflammatory Response and Chemokine Expression in the White Matter Corpus Callosum and Gray Matter Cortex Region During Cuprizone-Induced Demyelination

    J. P. Buschmann;K. Berger;H. Awad;T. Clarner

  • Dopamine regulates brain-derived neurotrophic factor (BDNF) expression in cultured embryonic mouse striatal cells.

    Eva Küppers;Cordian Beyer

  • Rapid Stimulation of the PI3‐Kinase/Akt Signalling Pathway in Developing Midbrain Neurones by Oestrogen

    T. Ivanova;Pablo Méndez;Luis M. García-Segura;C. Beyer

  • Effect of hypoxia on the transcription pattern of subunit isoforms and the kinetics of cytochrome c oxidase in cortical astrocytes and cerebellar neurons

    Susann Horvat;Cordian Beyer;Susanne Arnold

  • Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus.

    Akvile Norkute;Andrea Hieble;Alena Braun;Sonja Johann

  • Neuroprotection by estrogen in the brain: the mitochondrial compartment as presumed therapeutic target.

    Susanne Arnold;Cordian Beyer

Frequent Co-Authors

Markus Kipp
Markus Kipp University of Rostock
Beate Herpertz-Dahlmann
Beate Herpertz-Dahlmann RWTH Aachen University
Kerstin Konrad
Kerstin Konrad RWTH Aachen University
Martien J H Kas
Martien J H Kas University of Groningen
Keywan Mortezaee
Keywan Mortezaee Kurdistan University of Medical Sciences
Ute Habel
Ute Habel RWTH Aachen University
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Cornelia Exner
Cornelia Exner Leipzig University
Michael D. Wilson
Michael D. Wilson University of Toronto
Victor P.M.G. Rutten
Victor P.M.G. Rutten University of Pretoria

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