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2025

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Biology and Biochemistry

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Overview

Keywan Mortezaee is affiliated with Kurdistan University of Medical Sciences in Iran. Their research primarily spans Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these main fields, Mortezaee specializes in Oncology, Immunology, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

The scientist's research topics focus significantly on Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Immune cells in cancer, Extracellular vesicles in disease, and Cancer Cells and Metastasis.

Keywan Mortezaee has coauthored extensively with several researchers, including Jamal Majidpoor, Sajad Najafi, Masoud Najafi, Fardin Fathi, and Bagher Farhood. Collaboration with these coauthors has contributed to a significant body of work in their respective domains.

Frequent publication venues for Mortezaee include:

  • Biomedicine & Pharmacotherapy
  • Life Sciences
  • Medical Oncology
  • International Immunopharmacology
  • Cellular Oncology

Among the recent papers authored or coauthored by Keywan Mortezaee are:

  • "CXCL12/CXCR4 axis in the microenvironment of solid tumors: A critical mediator of metastasis" (2020) published in Life Sciences
  • "Immune escape: A critical hallmark in solid tumors" (2020) published in Life Sciences
  • "The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives" (2021) published in Clinical Immunology
  • "Steps in metastasis: an updated review" (2021) published in Medical Oncology
  • "Angiogenesis as a hallmark of solid tumors - clinical perspectives" (2021) published in Cellular Oncology

Mortezaee's body of work contains over one hundred publications in Medicine, with approximately fifty in Immunology and Microbiology and Biochemistry, Genetics and Molecular Biology. This reflects a consistent focus on cancer-related immunological mechanisms, metastasis, and tumor microenvironment dynamics.

Best Publications

  • CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review.

    Bagher Farhood;Masoud Najafi;Keywan Mortezaee

  • Cyclooxygenase-2 in cancer: A review.

    Nasser Hashemi Goradel;Masoud Najafi;Eniseh Salehi;Bagher Farhood

  • Extracellular matrix (ECM) stiffness and degradation as cancer drivers.

    Masoud Najafi;Bagher Farhood;Keywan Mortezaee

  • Cancer stem cells (CSCs) in cancer progression and therapy.

    Masoud Najafi;Bagher Farhood;Keywan Mortezaee

  • Macrophage polarity in cancer: A review.

    Masoud Najafi;Nasser Hashemi Goradel;Bagher Farhood;Eniseh Salehi

  • Cancer stem cell (CSC) resistance drivers.

    Masoud Najafi;Keywan Mortezaee;Jamal Majidpoor

  • Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy.

    Keywan Mortezaee;Ensieh Salehi;Hanifeh Mirtavoos‐mahyari;Elahe Motevaseli

  • Inflammasome: its role in traumatic brain and spinal cord injury†

    Keywan Mortezaee;Neda Khanlarkhani;Cordian Beyer;Adib Zendedel

  • Curcumin as an anti-inflammatory agent: Implications to radiotherapy and chemotherapy.

    Bagher Farhood;Keywan Mortezaee;Nasser Hashemi Goradel;Neda Khanlarkhani

  • Steps in metastasis: an updated review.

    Jamal Majidpoor;Keywan Mortezaee

  • Tumor microenvironment: Interactions and therapy.

    Masoud Najafi;Nasser Hashemi Goradel;Bagher Farhood;Eniseh Salehi

  • Angiogenesis as a hallmark of solid tumors - clinical perspectives

    Jamal Majidpoor;Keywan Mortezaee

  • Contribution of regulatory T cells to cancer: A review.

    Masoud Najafi;Bagher Farhood;Keywan Mortezaee

  • The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives.

    Jamal Majidpoor;Keywan Mortezaee

  • Fusobacterium nucleatum and colorectal cancer: A mechanistic overview

    Nasser Hashemi Goradel;Siamak Heidarzadeh;Samira Jahangiri;Bagher Farhood

  • Melatonin as an adjuvant in radiotherapy for radioprotection and radiosensitization

    B Farhood;N H Goradel;K Mortezaee;N Khanlarkhani

  • Transforming growth factor-β signaling: Tumorigenesis and targeting for cancer therapy.

    Amirhossein Ahmadi;Masoud Najafi;Bagher Farhood;Keywan Mortezaee

  • Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review.

    Keywan Mortezaee;Masoud Najafi;Hadi Samadian;Hamed Barabadi

  • Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review

    Keywan Mortezaee;Masoud Najafi;Bagher Farhood;Amirhossein Ahmadi

  • CXCL12/CXCR4 axis in the microenvironment of solid tumors: A critical mediator of metastasis.

    Keywan Mortezaee

Frequent Co-Authors

Masoud Najafi
Masoud Najafi Kermanshah University of Medical Sciences
Amirhossein Sahebkar
Amirhossein Sahebkar Mashhad University of Medical Sciences
Cordian Beyer
Cordian Beyer RWTH Aachen University
Ahmad Reza Dehpour
Ahmad Reza Dehpour Tehran University of Medical Sciences

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