D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 95 Citations 25,506 469 World Ranking 4697 National Ranking 2670

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

Gianfranco Alpini spends much of his time researching Internal medicine, Endocrinology, Cholangiocyte, Cholangiocyte proliferation and Cell biology. As part of his studies on Internal medicine, Gianfranco Alpini often connects relevant areas like Cell growth. His biological study focuses on Secretin.

His Cholangiocyte study improves the overall literature in Pathology. His Cholangiocyte proliferation research is multidisciplinary, relying on both Epithelium, Biliary tract, Apoptosis, Secretion and Intrahepatic bile ducts. The various areas that Gianfranco Alpini examines in his Cell biology study include Cell and Cell type.

His most cited work include:

  • Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. (281 citations)
  • Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans (275 citations)
  • Human hepatic stem cell and maturational liver lineage biology. (243 citations)

What are the main themes of his work throughout his whole career to date?

Gianfranco Alpini mainly investigates Internal medicine, Endocrinology, Cholangiocyte, Cancer research and Cell biology. Cholangiocyte proliferation, Secretin, Cholestasis, Intrahepatic bile ducts and Bile duct are the core of his Internal medicine study. He interconnects Receptor, Signal transduction, Apoptosis and Biliary tract in the investigation of issues within Endocrinology.

His Cholangiocyte research incorporates themes from Hepatic stellate cell, Secretion, Bile acid, Primary sclerosing cholangitis and Fibrosis. His work carried out in the field of Hepatic stellate cell brings together such families of science as Inflammation and Angiogenesis. His Cancer research research focuses on Liver injury and how it connects with Alcoholic liver disease.

He most often published in these fields:

  • Internal medicine (79.01%)
  • Endocrinology (70.85%)
  • Cholangiocyte (57.46%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (79.01%)
  • Cancer research (30.56%)
  • Endocrinology (70.85%)

In recent papers he was focusing on the following fields of study:

Internal medicine, Cancer research, Endocrinology, Cholangiocyte and Fibrosis are his primary areas of study. Many of his studies involve connections with topics such as Gastroenterology and Internal medicine. His studies deal with areas such as Inflammation, Receptor and Nonalcoholic fatty liver disease as well as Endocrinology.

His Cholangiocyte research integrates issues from Cell signaling, Hepatic fibrosis, Cholangiocyte proliferation, Bile acid and Primary sclerosing cholangitis. The concepts of his Fibrosis study are interwoven with issues in Molecular biology and Hepatic stellate cell. His Hepatic stellate cell study combines topics from a wide range of disciplines, such as Cell culture, Liver injury, Cell and Cell biology.

Between 2018 and 2021, his most popular works were:

  • Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances. (73 citations)
  • Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances. (73 citations)
  • Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances. (73 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

His scientific interests lie mostly in Internal medicine, Cholangiocyte, Hepatic stellate cell, Endocrinology and Cancer research. His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology and Desloratadine. Gianfranco Alpini has researched Cholangiocyte in several fields, including Cell signaling, G protein-coupled bile acid receptor, Biliary epithelium, Primary sclerosing cholangitis and Fibrosis.

His work deals with themes such as Liver injury and Cell biology, which intersect with Hepatic stellate cell. His studies in Endocrinology integrate themes in fields like Inflammation and Receptor. His biological study spans a wide range of topics, including Secretin, Secretin receptor and Transforming growth factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules.

G. Alpini;Renato Lenzi;L. Sarkozi;N. Tavoloni.
Journal of Clinical Investigation (1988)

433 Citations

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Alessia Omenetti;Alessandro Porrello;Youngmi Jung;Liu Yang.
Journal of Clinical Investigation (2008)

380 Citations

The Pathophysiology of Biliary Epithelia

Gianfranco Alpini;James M. McGill;Nicholas F. LaRusso.
(2004)

364 Citations

Human hepatic stem cell and maturational liver lineage biology.

Rachael Turner;Oswaldo Lozoya;Yunfang Wang;Vincenzo Cardinale.
Hepatology (2011)

328 Citations

Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver

Gianfranco Alpini;Stuart Roberts;Susan M. Kuntz;Yoshiyuki Ueno.
Gastroenterology (1996)

305 Citations

Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver.

Domenico Alvaro;Maria Grazia Mancino;Shannon Glaser;Eugenio Gaudio.
Gastroenterology (2007)

293 Citations

Recent advances in the isolation of liver cells

Gianfranco Alpini;John O. Phillips;Benjamin Vroman;Nicholas F. Larusso.
Hepatology (1994)

245 Citations

Fate-Mapping Evidence that Hepatic Stellate Cells are Epithelial Progenitors in Adult Mouse Livers

Liu Yang;Youngmi Jung;Alessia Omenetti;Rafal P. Witek.
Stem Cells (2008)

236 Citations

The biliary tree-a reservoir of multipotent stem cells

Vincenzo Cardinale;Yunfang Wang;Guido Carpino;Gemma Mendel.
Nature Reviews Gastroenterology & Hepatology (2012)

220 Citations

Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis.

Gene Lesage;Shannon Glaser;Yoshiyuki Ueno;Domenico Alvaro.
American Journal of Physiology-gastrointestinal and Liver Physiology (2001)

214 Citations

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