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Medicine

D-Index
94
Citations
27584
World Ranking
10598
National Ranking
5449

Overview

Hidekazu Tsukamoto is a researcher affiliated with the University of Southern California in the United States. Their work primarily focuses on medicine, with substantial contributions to biochemistry, genetics, and molecular biology. Their research spans a range of subfields including molecular biology, epidemiology, pathology and forensic medicine, immunology, and hepatology.

Tsukamoto's research topics cover several areas such as liver disease diagnosis and treatment, alcohol consumption and health effects, epigenetics and DNA methylation, liver physiology and pathology, lipid metabolism and biosynthesis, diet, metabolism and disease, as well as liver disease and transplantation.

Their recent publications reflect a significant engagement with hepatology and the biological impacts of alcohol consumption. Notable recent papers include:

  • "Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle" (2023, Proceedings of the National Academy of Sciences)
  • "Acetate reprograms gut microbiota during alcohol consumption" (2022, Nature Communications)
  • "Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis" (2020, Journal of Clinical Investigation)
  • "Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice" (2020, JCI Insight)
  • "Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice" (2020, Journal of Molecular Medicine)

Tsukamoto frequently publishes in several scientific journals, with multiple works appearing in iScience, UNC Libraries, Nature Communications, Journal of Clinical Investigation, and Hepatology Communications.

The scientist often collaborates with colleagues including Keigo Machida, Stanley M. Tahara, Stephanie Q. Pan, Yibu Chen, and Hye Yeon Choi. These coauthors have frequently contributed to the varied research outputs related to liver diseases and molecular biology.

Best Publications

  • Enteric dysbiosis associated with a mouse model of alcoholic liver disease

    Arthur W. Yan;Derrick E. Fouts;Johannes Brandl;Johannes Brandl;Peter Stärkel

  • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

    Tatiana Kisseleva;Min Cong;YongHan Paik;David Scholten

  • Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation

    Takeo Miyahara;Laura Schrum;Richard Rippe;Shigang Xiong

  • Experimental liver cirrhosis induced by alcohol and iron.

    Hidekazu Tsukamoto;Walter Horne;Seiichiro Kamimura;Onni Niemelä

  • Current concepts in the pathogenesis of alcoholic liver injury

    Hidekazu Tsukamoto;Shelly C. Lu

  • StellaTUM: current consensus and discussion on pancreatic stellate cell research

    Mert Erkan;Guido Adler;Minoti V. Apte;Max G. Bachem

  • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.

    Jelena Mann;David C.K. Chu;Aidan Maxwell;Fiona Oakley

  • Experimental models of hepatic fibrosis: a review.

    Hidekazu Tsukamoto;Masaki Matsuoka;Samuel W. French

  • Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.

    Junwei Gao;Juxing Chen;Maxwell Kramer;Hidekazu Tsukamoto;Hidekazu Tsukamoto

  • Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor β: Implication for a pathogenetic role in alcoholic liver fibrogenesis

    Masaki Matsuoka;Masaki Matsuoka;Hidekazu Tsukamoto

  • Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells

    Saswati Hazra;Shigang Xiong;Jiaohong Wang;Richard A. Rippe

  • Exacerbation of Alcoholic Liver Injury by Enteral Endotoxin in Rats

    Philippe Mathurin;Qing-Gao Deng;A. L. I. Keshavarzian;Sandeep Choudhary

  • Ethanol-induced liver fibrosis in rats fed high fat diet.

    H Tsukamoto;H Tsukamoto;H Tsukamoto;S J Towner;S J Towner;S J Towner;L M Ciofalo;L M Ciofalo;L M Ciofalo;S W French;S W French;S W French

  • Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis

    Jason H. Cheng;Hongyun She;Yuan-Ping Han;Jiaohong Wang

  • Adipogenic transcriptional regulation of hepatic stellate cells.

    Hongyun She;Hongyun She;Shigang Xiong;Saswati Hazra;Hidekazu Tsukamoto;Hidekazu Tsukamoto

  • Septum Transversum-Derived Mesothelium Gives Rise to Hepatic Stellate Cells and Perivascular Mesenchymal Cells in Developing Mouse Liver

    Kinji Asahina;Bin Zhou;Bin Zhou;William T. Pu;William T. Pu;Hidekazu Tsukamoto;Hidekazu Tsukamoto

  • Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

    Peng Chen;Manolito Torralba;Justin Tan;Mallory Embree

  • Inflammation in Alcoholic and Nonalcoholic Fatty Liver Disease: Friend or Foe?

    Bin Gao;Hidekazu Tsukamoto;Hidekazu Tsukamoto

  • Inflammatory pathways in alcoholic steatohepatitis.

    Bin Gao;Maleeha F. Ahmad;Laura E. Nagy;Laura E. Nagy;Hidekazu Tsukamoto

  • Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet

    Hidekazu Tsukamoto;Hidekazu Tsukamoto;Samuel W. French;Samuel W. French;Nancy Benson;Nancy Benson;George Delgado;George Delgado

Frequent Co-Authors

Samuel W. French
Samuel W. French UCLA Medical Center
David A. Brenner
David A. Brenner University of California, San Diego
Derek A. Mann
Derek A. Mann Newcastle University
Corey Largman
Corey Largman University of California, San Francisco
Bin Gao
Bin Gao National Institutes of Health
Caroline A. Enns
Caroline A. Enns Oregon Health & Science University
José C. Fernández-Checa
José C. Fernández-Checa University of Southern California
Gianfranco Alpini
Gianfranco Alpini Indiana University
Stephen J. Pandol
Stephen J. Pandol Cedars-Sinai Medical Center
Bernd Schnabl
Bernd Schnabl University of California, San Diego

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