World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
31415
World Ranking
2018
National Ranking
1101

Medicine

D-Index
94
Citations
31429
World Ranking
10506
National Ranking
5407

Overview

Shelly C. Lu is affiliated with Cedars-Sinai Medical Center in the United States and has a research focus spanning Medicine and Biochemistry, Genetics and Molecular Biology. Their work includes significant contributions to subfields such as Molecular Biology, Epidemiology, Hepatology, Oncology, and Cancer Research.

Major topics within Shelly C. Lu's research include:

  • Liver Disease Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Folate and B Vitamins Research
  • RNA modifications and cancer
  • Metabolomics and Mass Spectrometry Studies
  • Diet, Metabolism, and Disease
  • Alcohol Consumption and Health Effects

Their recent publications highlight diverse and impactful research areas. Selected papers include:

  • "Detection of Circulating Tumor Cells and Their Implications as a Biomarker for Diagnosis, Prognostication, and Therapeutic Monitoring in Hepatocellular Carcinoma" (2020), published in Hepatology
  • "SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum" (2020), published in iScience
  • "Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-2018" (2021), published in JAMA
  • "Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment" (2023), published in Cell Metabolism
  • "Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly" (2020), published in Cell Metabolism

Frequent coauthors in Shelly C. Lu's research include José M. Mato, Ju Dong Yang, Óscar Millet, Nicholas N. Nissen, and Ekihiro Seki.

The scientist's work is commonly published in venues such as Gastroenterology, Hepatology, Journal of Hepatology, SSRN Electronic Journal, and Nature Communications, reflecting a strong presence in journals focused on liver disease and related biomedical research.

Best Publications

  • REGULATION OF GLUTATHIONE SYNTHESIS

    Shelly C. Lu

  • Regulation of hepatic glutathione synthesis: current concepts and controversies

    Shelly C. Lu

  • Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes

    Javier Conde-Vancells;Eva Rodriguez-Suarez;Nieves Embade;David Gil

  • Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

    Shelly C. Lu;Luis Alvarez;Zong-Zhi Huang;Lixin Chen

  • S-Adenosylmethionine: a control switch that regulates liver function

    José M. Mato;Fernando J. Corrales;Shelly C. Lu;Matías A. Avila

  • S-adenosylmethionine in Liver Health, Injury, and Cancer

    Shelly C. Lu;José M. Mato

  • Current concepts in the pathogenesis of alcoholic liver injury

    Hidekazu Tsukamoto;Shelly C. Lu

  • NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances.

    Mazen Noureddin;Aarshi Vipani;Catherine Bresee;Tsuyoshi Todo

  • Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.

    Matías A Avila;Carmen Berasain;Luis Torres;Antonio Martín-Duce

  • Role of S‐adenosyl‐L‐methionine in liver health and injury

    José M. Mato;Shelly C. Lu

  • Methionine Metabolism and Liver Disease

    José M Mato;M Luz Martínez-Chantar;Shelly C Lu

  • Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice†

    M. Luz Martínez-Chantar;Mercedes Vázquez-Chantada;Usue Ariz;Nuria Martínez

  • Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

    Maria L. Martínez-Chantar;Fernando J. Corrales;L. Alfonso Martínez-Cruz;Elena R. García-Trevijano

  • Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes.

    Maria T. Runnegar;Shou-Ming Kong;Ya-Zhen Zhong;Shelly C. Lu

  • Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort.

    Veronica Wendy Setiawan;Daniel O. Stram;Jacqueline Porcel;Shelly C. Lu

  • Nrf1 and Nrf2 Regulate Rat Glutamate-Cysteine Ligase Catalytic Subunit Transcription Indirectly via NF-κB and AP-1

    Heping Yang;Nathaniel Magilnick;Candy Lee;Denise Kalmaz

  • S-adenosylmethionine stabilizes cystathionine β-synthase and modulates redox capacity

    Anna Prudova;Zachary Bauman;Aaron Braun;Victor Vitvitsky

  • Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration.

    Zong-Zhi Huang;Changjin Chen;Zhaohui Zeng;Heping Yang

  • S-Adenosylmethionine in cell growth, apoptosis and liver cancer

    Shelly C Lu;José M Mato

  • Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver

    Shelly C. Lu;Zong-Zhi Huang;Heping Yang;José M. Mato

Frequent Co-Authors

José M. Mato
José M. Mato CIC bioGUNE
Matías A. Avila
Matías A. Avila University of Navarra
Conrad Wagner
Conrad Wagner Vanderbilt University
Samuel W. French
Samuel W. French UCLA Medical Center
Hidekazu Tsukamoto
Hidekazu Tsukamoto University of Southern California
Neil Kaplowitz
Neil Kaplowitz University of Southern California
Juan Anguita
Juan Anguita Ikerbasque
Loic Le Marchand
Loic Le Marchand University of Hawaii at Manoa
Mario F. Fraga
Mario F. Fraga University of Oviedo

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