World's Best Scientists 2026 revealed!

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Chemistry

D-Index
96
Citations
29281
World Ranking
1576
National Ranking
604

Biology and Biochemistry

D-Index
96
Citations
29718
World Ranking
1847
National Ranking
1015

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ruma Banerjee is affiliated with the University of Michigan-Ann Arbor in the United States and works primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Molecular Biology, Biochemistry, Rheumatology, Physiology, and Cancer Research.

The scientist's work focuses on topics such as Sulfur Compounds in Biology, Folate and B Vitamins Research, Porphyrin Metabolism and Disorders, Heme Oxygenase-1 and Carbon Monoxide, Cancer, Hypoxia, and Metabolism, Neuroscience of respiration and sleep, and Alcohol Consumption and Health Effects.

They have published extensively in various scientific journals, with frequent publication venues including:

  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Free Radical Biology and Medicine
  • Journal of the American Chemical Society

Notable recent papers include:

  • "HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron," 2021, Journal of Clinical Investigation
  • "Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer," 2022, Cell Metabolism
  • "Hydrogen Sulfide Oxidation by Sulfide Quinone Oxidoreductase," 2020, ChemBioChem
  • "A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H2S oxidation," 2021, Journal of Biological Chemistry
  • "Redox-Linked Coordination Chemistry Directs Vitamin B12 Trafficking," 2021, Accounts of Chemical Research

Frequent collaborators in their research include Eric R. Fearon, Lila M. Gierasch, F. Peter Guengerich, Roger Colbran, and Peter Cresswell. These collaborations reflect a network of interdisciplinary work, especially in biochemical and molecular studies.

Over the course of their career, Ruma Banerjee has contributed to 129 publications within the broad scope of Biochemistry, Genetics and Molecular Biology, indicating a significant research output. Their scientific inquiries intersect biochemical pathways, molecular mechanisms, and disease-related processes.

In recognition of their scientific contributions, they were awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Chemical Biology of H2S Signaling through Persulfidation.

    Milos R. Filipovic;Jasmina Zivanovic;Beatriz Alvarez;Ruma Banerjee

  • The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes.

    Ruma Banerjee;Stephen W. Ragsdale

  • Redox Biochemistry of Hydrogen Sulfide

    Omer Kabil;Ruma Banerjee

  • Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

    Sangita Singh;Dominique Padovani;Rachel A. Leslie;Taurai Chiku

  • The Quantitatively Important Relationship between Homocysteine Metabolism and Glutathione Synthesis by the Transsulfuration Pathway and Its Regulation by Redox Changes

    Eugene Mosharov;Matthew R. Cranford;Ruma Banerjee

  • Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

    Tatiana V Mishanina;Marouane Libiad;Ruma Banerjee

  • Cobalamin-dependent methionine synthase.

    Ruma V. Banerjee;Rowena G. Matthews

  • Chemistry and biochemistry of B12

    Ruma Banerjee

  • Selective fluorescent probes for live-cell monitoring of sulphide

    Yong Qian;Jason Karpus;Omer Kabil;Shu Yu Zhang;Shu Yu Zhang

  • H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

    Taurai Chiku;Dominique Padovani;Weidong Zhu;Sangita Singh;Sangita Singh

  • Enzymology of H2S biogenesis, decay and signaling.

    Omer Kabil;Ruma Banerjee

  • Radical carbon skeleton rearrangements: catalysis by coenzyme B12-dependent mutases.

    Ruma Banerjee

  • Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity.

    Shinichi Taoka;Sunil Ohja;Xiaoyin Shan;Warren D. Kruger

  • H2S and its role in redox signaling

    Omer Kabil;Nicole Motl;Ruma Banerjee

  • The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

    Omer Kabil;Victor Vitvitsky;Peter Xie;Ruma Banerjee

  • A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis

    Victor Vitvitsky;Mark Thomas;Mark Thomas;Anuja Ghorpade;Howard Eliot Gendelman;Howard Eliot Gendelman

  • Redox regulation and reaction mechanism of human cystathionine-β-synthase: a PLP-dependent hemesensor protein☆

    Ruma Banerjee;Cheng Gang Zou

  • S-adenosylmethionine stabilizes cystathionine β-synthase and modulates redox capacity

    Anna Prudova;Zachary Bauman;Aaron Braun;Victor Vitvitsky

  • Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase.

    Pramod Kumar Yadav;Kazuhiro Yamada;Taurai Chiku;Markos Koutmos

  • Decyanation of vitamin B12 by a trafficking chaperone

    Jihoe Kim;Carmen Gherasim;Ruma Banerjee

  • Characterization of NO binding to human cystathionine β-synthase:: Possible implications of the effects of CO and NO binding to the human enzyme

    Shinichi Taoka;Ruma Banerjee

  • Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease.

    N. M. J. Van Der Put;E. F. Van Der Molen;L. A. J. Kluijtmans;S. G. Heil

Frequent Co-Authors

David P. Ballou
David P. Ballou University of Michigan–Ann Arbor
Milos R. Filipovic
Milos R. Filipovic Leibniz Institute for Neurobiology
Donald W. Jacobsen
Donald W. Jacobsen Cleveland Clinic Lerner College of Medicine
Thomas C. Brunold
Thomas C. Brunold University of Wisconsin–Madison
Beatriz Alvarez
Beatriz Alvarez University of the Republic
Rowena G. Matthews
Rowena G. Matthews University of Michigan–Ann Arbor
Bernhard Kräutler
Bernhard Kräutler University of Innsbruck
Thomas G. Spiro
Thomas G. Spiro University of Washington
Janet L. Smith
Janet L. Smith University of Michigan–Ann Arbor
Howard E. Gendelman
Howard E. Gendelman University of Nebraska Medical Center

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