Jan P. Kraus

Overview

Best Publications

• Cystathionine β‐synthase mutations in homocystinuria

  Jan P. Kraus;Miroslav Janošík;Viktor Kožich;Roseann Mandell

  408
  Citations

• Structure of human cystathionine β-synthase: a unique pyridoxal 5′-phosphate-dependent heme protein

  Markus Meier;Miroslav Janosik;Vladimir Kery;Jan P. Kraus

  378
  Citations

• Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA.

  Eleanor K. Spicer;Renata Horton;Laura Bloem;Ronald Bach

  367
  Citations

• Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.

  Arthur L. Horwich;Wayne A. Fenton;Kenneth R. Williams;Frantisek Kalousek

  347
  Citations

• Cystathionine β-Synthase: Structure, Function, Regulation, and Location of Homocystinuria-causing Mutations

  Edith Wilson Miles;Jan P. Kraus

  326
  Citations

• Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.

  V Kery;G Bukovska;J P Kraus

  251
  Citations

• The molecular basis of homocystinuria due to cystathionine beta-synthase deficiency in Italian families, and report of four novel mutations.

  G Sebastio;M P Sperandeo;M Panico;R de Franchis

  238
  Citations

• Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.

  Y Matsubara;Y Indo;E Naito;H Ozasa

  218
  Citations

• Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region.

  Miroslav Janošík;Vladimír Kery;Mette Gaustadnes;Kenneth N. Maclean

  216
  Citations

• Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

  Katheleen Gardiner;Michel Horisberger;Jan Kraus;Umadevi Tantravahi

  213
  Citations

• Propionic acidemia: clinical course and outcome in 55 pediatric and adolescent patients

  Sarah C. Grünert;Stephanie Müllerleile;Linda De Silva;Michael Barth

  202
  Citations

• Trypsin Cleavage of Human Cystathionine β-Synthase into an Evolutionarily Conserved Active Core: Structural and Functional Consequences

  Vladimir Kery;Loelle Poneleit;Jan P. Kraus

  195
  Citations

• Hormonal Regulation of Cystathionine β-Synthase Expression in Liver

  Shobhitha Ratnam;Kenneth N. Maclean;Rene L. Jacobs;Margaret E. Brosnan

  190
  Citations

• Rat cystathionine beta-synthase. Gene organization and alternative splicing.

  M Swaroop;K Bradley;T Ohura;T Tahara

  180
  Citations

• Identification of Cystathionine β‐Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe

  Megan K. Thorson;Tomas Majtan;Jan P. Kraus;Amy M. Barrios

  174
  Citations

• The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17.

  M Münke;J P Kraus;T Ohura;U Francke

  173
  Citations

• The human cystathionine β-synthase (CBS) gene : complete sequence, alternative splicing, and polymorphisms

  Jan P. Kraus;Jana Oliveriusová;Jana Oliveriusová;Jitka Sokolová;Eva Kraus

  164
  Citations

• Identification and tissue distribution of human cystathionine beta-synthase mRNA isoforms.

  Liming Bao;Čestmı́r Vlček;Václav Pačes;Jan P. Kraus

  155
  Citations

• Homocystinuria. Evidence for three distinct classes of cystathionine beta-synthase mutants in cultured fibroblasts.

  Brian Fowler;Jan Kraus;Seymour Packman;Leon E. Rosenberg

  148
  Citations

• Human cystathionine β-synthase cDNA: sequence, alternative splicing and expression in cultured cells

  J P Kraus;K Le;M Swaroop;T Ohura

  144
  Citations