Kay Tanaka

Overview

Best Publications

• Isovaleric acidemia: a new genetic defect of leucine metabolism.

  K Tanaka;M A Budd;M L Efron;K J Isselbacher

  464
  Citations

• Medium-chain acyl-CoA dehydrogenase deficiency.

  Piero Rinaldo;John J. O'Shea;Paul M. Coates;Daniel E. Hale

  292
  Citations

• Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme.

  Y Ikeda;K Okamura-Ikeda;K Tanaka

  291
  Citations

• Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.

  Y Matsubara;Y Indo;E Naito;H Ozasa

  218
  Citations

• Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients.

  Toshifumi Aoyama;Masayoshi Souri;Seiichi Ushikubo;Takehiko Kamijo

  181
  Citations

• Identification of very-long-chain acyl-CoA dehydrogenase deficiency in three patients previously diagnosed with long-chain acyl-CoA dehydrogenase deficiency

  Seiji Yamaguchi;Yasuhiro Indo;Paul M Coates;Takashi Hashimoto

  160
  Citations

• Ethylmalonic-Adipic Aciduria: IN VIVO AND IN VITRO STUDIES INDICATING DEFICIENCY OF ACTIVITIES OF MULTIPLE ACYL-CoA DEHYDROGENASES

  Stephanos Mantagos;Myron Genel;Kay Tanaka

  145
  Citations

• Prenatal therapy of a patient with vitamin-B12-responsive methylmalonic acidemia.

  Mary G. Ampola;Maurice J. Mahoney;Eiichi Nakamura;Kay Tanaka

  141
  Citations

• Molecular survey of a prevalent mutation, 985A-to-G transition, and identification of five infrequent mutations in the medium-chain Acyl-CoA dehydrogenase (MCAD) gene in 55 patients with MCAD deficiency.

  Ichiro Yokota;Paul M. Coates;Daniel E. Hale;Piero Rinaldo

  132
  Citations

• Molecular basis of medium chain acyl-coenzyme A dehydrogenase deficiency. An A to G transition at position 985 that causes a lysine-304 to glutamate substitution in the mature protein is the single prevalent mutation.

  I Yokota;Y Indo;P M Coates;K Tanaka

  129
  Citations

• FAD-dependent regulation of transcription, translation, post-translational processing, and post-processing stability of various mitochondrial acyl-CoA dehydrogenases and of electron transfer flavoprotein and the site of holoenzyme formation.

  M Nagao;K Tanaka

  124
  Citations

• Developmental, nutritional, and hormonal regulation of tissue-specific expression of the genes encoding various acyl-CoA dehydrogenases and alpha-subunit of electron transfer flavoprotein in rat.

  M Nagao;B Parimoo;K Tanaka

  121
  Citations

• Isovaleric and α-Methylbutyric Acidemias Induced by Hypoglycin A: Mechanism of Jamaican Vomiting Sickness

  Kay Tanaka;Kurt J. Isselbacher;Vivian Shih

  118
  Citations

• Association of SIGNR1 with TLR4–MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria

  Koji Nagaoka;Kazuhiko Takahara;Kay Tanaka;Hideo Yoshida

  114
  Citations

• Purification and properties of short-chain acyl-CoA, medium-chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver.

  Finocchiaro G;Ito M;Tanaka K

  107
  Citations

• Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene.

  K. Tanaka;I. Yokota;P. M. Coates;A. W. Strauss

  102
  Citations

• Molecular cloning and nucleotide sequence of complementary DNAs encoding human short chain acyl-coenzyme A dehydrogenase and the study of the molecular basis of human short chain acyl-coenzyme A dehydrogenase deficiency.

  E Naito;H Ozasa;Y Ikeda;K Tanaka

  101
  Citations

• Identification of two variant short chain acyl-coenzyme A dehydrogenase alleles, each containing a different point mutation in a patient with short chain acyl-coenzyme A dehydrogenase deficiency.

  Etsuo Naito;Yasuhiro Indo;Kay Tanaka

  101
  Citations

• Demonstration of a specific mitochondrial isovaleryl-CoA dehydrogenase deficiency in fibroblasts from patients with isovaleric acidemia

  William J. Rhead;Kay Tanaka

  100
  Citations

• Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients.

  T Aoyama;M Souri;I Ueno;T Kamijo

  100
  Citations