World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
104
Citations
50303
World Ranking
6947
National Ranking
3658

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Daniel P. Kelly is affiliated with the University of Pennsylvania in the United States. Their research spans across several fields of study, predominantly focusing on Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader fields, their work delves into subfields such as Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Surgery, and Cancer Research.

Their main research topics reflect a strong emphasis on metabolic and cardiovascular processes. These include diet and metabolism studies, cardiovascular function and risk factors, adipose tissue and metabolism, mitochondrial function and pathology, cancer, hypoxia, and metabolism, metabolomics and mass spectrometry studies, as well as heart failure treatment and management.

Daniel P. Kelly has contributed notably to peer-reviewed journals, with frequent publications in prominent venues including:

  • Circulation
  • Circulation Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JACC Basic to Translational Science
  • Journal of the American College of Cardiology

Their recent scholarly articles highlight ongoing investigations in cardiovascular metabolism and heart failure. Selected recent papers include:

  • Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction, 2023, Circulation
  • Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease, 2021, Journal of the American College of Cardiology
  • Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure, 2020, Circulation
  • Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure, 2020, Circulation Heart Failure
  • A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation, 2020, Circulation Research

The scientist has collaborated extensively with several frequent co-authors, including Kenneth B. Margulies, Zoltàn Arany, Tomoya Sakamoto, Timothy Matsuura, and Teresa C. Leone. These collaborations underline a network of research in cardiovascular and molecular biology topics.

Among their recognitions, Daniel P. Kelly is a member of the Association of American Physicians. This affiliation reflects their professional engagement within the medical research community.

Best Publications

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Kerstin Howe;Matthew D. Clark;Carlos F. Torroja;Carlos F. Torroja;James Torrance

  • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

    Brian N. Finck;Daniel P. Kelly

  • Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis

    John J. Lehman;Philip M. Barger;Attila Kovacs;Jeffrey E. Saffitz

  • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

    Daniel P. Kelly;Richard C. Scarpulla

  • The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes.

    Rick B. Vega;Janice M. Huss;Daniel P. Kelly

  • Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1

    Keith Baar;Adam R. Wende;Terry E. Jones;Matthew Marison

  • PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

    Teresa C Leone;John J Lehman;Brian N Finck;Paul J Schaeffer

  • The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

    Brian N. Finck;John J. Lehman;Teresa C. Leone;Michael J. Welch

  • A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders.

    Teresa C. Leone;Carla J. Weinheimer;Daniel P. Kelly

  • Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1

    Laura F. Michael;Zhidan Wu;R. Bentley Cheatham;Pere Puigserver

  • Transcriptional integration of mitochondrial biogenesis.

    Richard C. Scarpulla;Rick B. Vega;Daniel P. Kelly

  • Fatty Acid Oxidation Enzyme Gene Expression Is Downregulated in the Failing Heart

    Michael N. Sack;Toni A. Rader;Sonhee Park;Jean Bastin

  • THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR REGULATES MITOCHONDRIAL FATTY ACID OXIDATIVE ENZYME GENE EXPRESSION

    Tod Gulick;Sharon Cresci;Teresa Caira;David D. Moore

  • Peroxisome Proliferator-activated Receptor Coactivator-1α (PGC-1α) Coactivates the Cardiac-enriched Nuclear Receptors Estrogen-related Receptor-α and -γ IDENTIFICATION OF NOVEL LEUCINE-RICH INTERACTION MOTIF WITHIN PGC-1α

    Janice M. Huss;Ryan P. Kopp;Daniel P. Kelly

  • Mitochondrial energy metabolism in heart failure: a question of balance

    Janice M. Huss;Daniel P. Kelly

  • Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway

    Brian N. Finck;Matthew C. Gropler;Zhouji Chen;Teresa C. Leone

  • A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content

    Brian N. Finck;Xianlin Han;Michael Courtois;Franck Aimond

  • The Failing Heart Relies on Ketone Bodies as a Fuel

    Gregory Aubert;Ola J. Martin;Julie L. Horton;Ling Lai

  • Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy

    Víctor G. Dávila-Román;Giridhar Vedala;Pilar Herrero;Lisa de las Fuentes

  • PPAR signaling in the control of cardiac energy metabolism.

    Philip M Barger;Daniel P Kelly

Frequent Co-Authors

Brian N. Finck
Brian N. Finck Washington University in St. Louis
Arnold W. Strauss
Arnold W. Strauss Cincinnati Children's Hospital Medical Center
Xianlin Han
Xianlin Han The University of Texas Health Science Center at San Antonio
Deborah M. Muoio
Deborah M. Muoio Duke University
Gary D. Lopaschuk
Gary D. Lopaschuk University of Alberta
Kenneth B. Margulies
Kenneth B. Margulies University of Pennsylvania
Clay F. Semenkovich
Clay F. Semenkovich Washington University in St. Louis
Vincent Giguère
Vincent Giguère McGill University
Gerald W. Dorn
Gerald W. Dorn Washington University in St. Louis
Zoltan Arany
Zoltan Arany University of Pennsylvania

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The landscape of medical education is evolving rapidly to include more flexible study options. For those exploring alternatives to traditional medical school pathways, there are high-quality online degrees that open doors to rewarding healthcare careers.

Aspiring healthcare administrators may consider cahme accredited online Master of Healthcare Administration (MHA) programs. These programs provide rigorous training in healthcare leadership while offering the flexibility of online study.

Registered nurses looking to advance their qualifications without relocating or taking time off work can benefit from the rn to bsn online no clinicals accredited options. These degrees allow RNs to complete their baccalaureate entirely online, with no additional clinical hours required.

Nurses aiming for the highest practice roles may seek doctoral-level credentials through the shortest online dnp program or explore the easiest dnp program online for streamlined pathways to a Doctor of Nursing Practice (DNP) degree.

These online options provide diverse paths for healthcare professionals to grow their careers and make a broader impact in medicine and patient care.

Best Scientists Citing Daniel P. Kelly

Trending Scientists

Recently Published Articles