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Vincent Giguère

Vincent Giguère

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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
40595
World Ranking
1250
National Ranking
32

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2009 - Fellow of the Royal Society of Canada Academy of Science

Overview

Vincent Giguère is affiliated with McGill University in Canada and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Their research spans various subfields including Molecular Biology, Physiology, Genetics, Epidemiology, and Pulmonary and Respiratory Medicine.

Their work has addressed multiple topics, notably Estrogen and related hormone effects, Adipose Tissue and Metabolism, Genomics, phytochemicals, and oxidative stress, Prostate Cancer Treatment and Research, Liver Disease Diagnosis and Treatment, Retinoids in leukemia and cellular processes, and Antioxidant Activity and Oxidative Stress.

Among their recent publications are:

  • Transcriptional control of energy metabolism by nuclear receptors, 2022, Nature Reviews Molecular Cell Biology
  • Estrogen-related receptors are targetable ROS sensors, 2020, Genes & Development
  • Aging, senescence and mitochondria: the PGC-1/ERR axis, 2020, Journal of Molecular Endocrinology
  • ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP, 2022, Nature Metabolism
  • Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4, 2020, Oncogene

Vincent Giguère has collaborated frequently with several co-authors, including Catherine R. Dufour, Charlotte Scholtes, Mathieu Vernier, Hui Xia, and Étienne Audet-Walsh.

Their work has been published in multiple venues repeatedly, such as bioRxiv (Cold Spring Harbor Laboratory), Molecular Metabolism, Journal of Molecular Endocrinology, Oncogene, and Genes & Development.

In recognition of their scientific contributions, Vincent Giguère was named a Fellow of the Royal Society of Canada in 2009, cited by the Academy of Science.

Best Publications

  • Identification of a receptor for the morphogen retinoic acid.

    Vincent Giguere;Estelita S. Ong;Prudimar Segui;Ronald M. Evans

  • Functional domains of the human glucocorticoid receptor

    Vincent Giguère;Stanley M. Hollenberg;Michael G. Rosenfeld;Ronald M. Evans

  • Orphan nuclear receptors: from gene to function.

    Vincent Giguère

  • Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor β

    Gilles B. Tremblay;André Tremblay;Neal G. Copeland;Debra J. Gilbert

  • A unified nomenclature system for the nuclear receptor superfamily

    J. Auwerx;E. Baulieu;M. Beato;M. Becker-Andre

  • Identification of a new class of steroid hormone receptors

    Vincent Giguère;Na Yang;Na Yang;Prudimar Segui;Ronald M. Evans

  • Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors

    Fabienne Guillaumond;Hugues Dardente;Vincent Giguère;Nicolas Cermakian

  • Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis.

    J Rossant;R Zirngibl;D Cado;M Shago

  • Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling.

    Vincent Giguère

  • Retinoic acid and thyroid hormone induce gene expression through a common responsive element

    Kazuhiko Umesono;Vincent Giguere;Christopher K. Glass;Michael G. Rosenfeld;Michael G. Rosenfeld

  • Ligand-Independent Recruitment of SRC-1 to Estrogen Receptor β through Phosphorylation of Activation Function AF-1

    André Tremblay;Gilles B Tremblay;Fernand Labrie;Vincent Giguère;Vincent Giguère

  • Transcriptional control of energy homeostasis by the estrogen-related receptors.

    Vincent Giguère

  • Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor.

    Stanley M Hollenberg;Vincent Giguere;Prudimar Segui;Ronald M Evans

  • Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

    Vincent Giguere;Mark Tini;Grace Flock;Estelita Ong

  • Estrogen-Related Receptor α Directs Peroxisome Proliferator-Activated Receptor α Signaling in the Transcriptional Control of Energy Metabolism in Cardiac and Skeletal Muscle

    Janice M. Huss;Inés Pineda Torra;Bart Staels;Vincent Giguère

  • International Union of Pharmacology. LXV. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Glucocorticoid, Mineralocorticoid, Progesterone, and Androgen Receptors

    Nick Z. Lu;Suzanne E. Wardell;Kerry L. Burnstein;Donald Defranco

  • From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response.

    Josée Laganière;Geneviève Deblois;Céline Lefebvre;Alain R. Bataille

  • To ERR in the estrogen pathway.

    Vincent Giguére

  • Genome-wide Orchestration of Cardiac Functions by the Orphan Nuclear Receptors ERRα and γ

    Catherine R. Dufour;Brian J. Wilson;Janice M. Huss;Daniel P. Kelly

  • Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta

    Jiangming Luo;Robert Sladek;Jo-Ann Bader;Annie Matthyssen

Frequent Co-Authors

Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Fernand Labrie
Fernand Labrie Université Laval
Kazuhiko Umesono
Kazuhiko Umesono Kyoto University
Julie St-Pierre
Julie St-Pierre McGill University
Janet Rossant
Janet Rossant University of Toronto
William J. Muller
William J. Muller McGill University
Tso-Pang Yao
Tso-Pang Yao Duke University
Robert Sladek
Robert Sladek McGill University
Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Guillaume Bourque
Guillaume Bourque McGill University

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