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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
37611
World Ranking
8023
National Ranking
3634

Overview

Tso-Pang Yao is affiliated with Duke University in the United States and has made contributions primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses several subfields including molecular biology, epidemiology, cell biology, oncology, and neurology.

The main topics addressed in their work include:

  • Autophagy in Disease and Therapy
  • Histone Deacetylase Inhibitors Research
  • Lipid metabolism and biosynthesis
  • Hippo pathway signaling and YAP/TAZ
  • Cancer-related Molecular Pathways
  • Cell death mechanisms and regulation
  • Parkinson's Disease Mechanisms and Treatments

Their recent papers cover a range of research areas and have been published in recognized scientific journals. Notable papers include:

  • "RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence," 2020, Cell Death and Differentiation
  • "Parkin coordinates mitochondrial lipid remodeling to execute mitophagy," 2022, EMBO Reports
  • "Discovery of the First Irreversible HDAC6 Isoform Selective Inhibitor with Potent Anti-Multiple Myeloma Activity," 2023, Journal of Medicinal Chemistry
  • "Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype," 2023, Advanced Science
  • "Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway-implications for Parkinson's disease," 2022, Human Molecular Genetics

Throughout their publications, several collaborators have frequently worked with Tso-Pang Yao. These co-authors include:

  • Chao-Chieh Lin
  • Jen-Tsan Chi
  • Meghan Kapur
  • Kah-Leong Lim
  • Jin Yan

The preferred publication venues where their work appears are diverse and include:

  • Cell Death and Differentiation
  • EMBO Reports
  • Journal of Medicinal Chemistry
  • Advanced Science
  • Human Molecular Genetics

The focus in many studies involves cellular mechanisms such as autophagy and lipid metabolism, as well as therapeutic targets such as histone deacetylase inhibitors. Their research also explores molecular pathways linked to cancer and neurological conditions such as Parkinson's disease.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • HDAC6 is a microtubule-associated deacetylase

    Charlotte Hubbert;Amaris Guardiola;Rong Shao;Yoshiharu Kawaguchi

  • The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress

    Yoshiharu Kawaguchi;Jeffrey J. Kovacs;Adam McLaurin;Jeffery M. Vance

  • HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

    Udai Bhan Pandey;Zhiping Nie;Yakup Batlevi;Brett A. McCray

  • HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

    Jeffrey J. Kovacs;Patrick J.M. Murphy;Stéphanie Gaillard;Xuan Zhao

  • Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

    David No;Tso-Pang Yao;Ronald M. Evans

  • Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

    Tso Pang Yao;Suk P. Oh;Miriam Fuchs;Nai Dong Zhou

  • Role of T-bet in Commitment of TH1 Cells Before IL-12-Dependent Selection

    Alan C. Mullen;Frances A. High;Anne S. Hutchins;Hubert W. Lee

  • Functional Ecdysone Receptor Is the Product of EcR and Ultraspiracle Genes

    Tso-Pang Yao;B. M. Forman;Zeyu Jiang;L. Cherbas

  • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

    Tso Pang Yao;William A. Segraves;Anthony E. Oro;Anthony E. Oro;Michael McKeown

  • HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

    Joo Yong Lee;Hiroshi Koga;Yoshiharu Kawaguchi;Waixing Tang

  • HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin

    Xiaohong Zhang;Zhigang Yuan;Yingtao Zhang;Sarah Yong

  • p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2

    Akihiro Ito;Chun‐Hsiang Lai;Chun‐Hsiang Lai;Xuan Zhao;Xuan Zhao;Shin'ichi Saito

  • MDM2–HDAC1-mediated deacetylation of p53 is required for its degradation

    Akihiro Ito;Yoshiharu Kawaguchi;Chun-Hsiang Lai;Jeffrey J. Kovacs

  • The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

    Tso-Pang Yao;Gregory Ku;Naidong Zhou;Ralph Scully

  • Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

    Joo-Yong Lee;Yoshito Nagano;J. Paul Taylor;Kah Leong Lim

  • Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

    Andrew L. Kung;Vivienne I. Rebel;Roderick T. Bronson;Lian Ee Ch'ng

  • VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.

    Emilie Tresse;Florian A. Salomons;Jouni Vesa;Laura C. Bott

  • Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.

    R Eckner;T P Yao;E Oldread;D M Livingston

  • Short Article HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

    Jeffrey J. Kovacs;Stéphanie Gaillard;Xuan Zhao;June-Tai Wu

Frequent Co-Authors

Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Anthony E. Oro
Anthony E. Oro Stanford University
J. Paul Taylor
J. Paul Taylor St. Jude Children's Research Hospital
Kah-Leong Lim
Kah-Leong Lim Nanyang Technological University
Vincent Giguère
Vincent Giguère McGill University
David M. Livingston
David M. Livingston Harvard University
Minoru Yoshida
Minoru Yoshida University of Tokyo
Edward Seto
Edward Seto George Washington University
Jen-Tsan Chi
Jen-Tsan Chi Duke University
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center

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