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Molecular Biology
UK
2026
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Biology and Biochemistry
UK
2023

D-Index & Metrics

Molecular Biology

D-Index
158
Citations
155368
World Ranking
68
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2025 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2022 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2017 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

David C. Rubinsztein is affiliated with the University of Cambridge in the United Kingdom. Their research spans across multiple fields, including Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on subfields such as Epidemiology, Molecular Biology, Cell Biology, Physiology, and Neurology.

The main topics of their research include:

  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Cellular transport and secretion
  • Parkinson's Disease Mechanisms and Treatments
  • Lysosomal Storage Disorders Research
  • Alzheimer's disease research and treatments
  • Ubiquitin and proteasome pathways

Frequent co-authors collaborating with David C. Rubinsztein are:

  • Sung Min Son
  • Lidia Wróbel
  • Angeleen Fleming
  • Cansu Karabiyik
  • Claudia Puri

The scientist often publishes in venues such as:

  • Autophagy
  • Developmental Cell
  • Neuron
  • Nature Communications
  • Nature Cell Biology

Notable recent papers include:

  • "Autophagy in major human diseases", 2021, The EMBO Journal
  • "Autophagy in healthy aging and disease", 2021, Nature Aging
  • "The different autophagy degradation pathways and neurodegeneration", 2022, Neuron
  • "Mechanisms of autophagy-lysosome dysfunction in neurodegenerative diseases", 2024, Nature Reviews Molecular Cell Biology
  • "VCP/p97 regulates Beclin-1-dependent autophagy initiation", 2021, Nature Chemical Biology

David C. Rubinsztein has received several honors including:

  • Fellow of the Royal Society, United Kingdom (2017)
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • TFEB links autophagy to lysosomal biogenesis.

    Carmine Settembre;Chiara Di Malta;Vinicia Assunta Polito;Vinicia Assunta Polito;Moises Garcia Arencibia

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

    Brinda Ravikumar;Coralie Vacher;Zdenek Berger;Janet E Davies

  • Autophagy and Aging

    David C. Rubinsztein;Guillermo Mariño;Guillermo Mariño;Guillermo Mariño;Guido Kroemer

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Regulation of Mammalian Autophagy in Physiology and Pathophysiology

    Brinda Ravikumar;Sovan Sarkar;Janet E. Davies;Marie Futter

  • The roles of intracellular protein-degradation pathways in neurodegeneration

    David C. Rubinsztein

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • α-Synuclein Is Degraded by Both Autophagy and the Proteasome *

    Julie L. Webb;Brinda Ravikumar;Jane Atkins;Jeremy N. Skepper

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy modulation as a potential therapeutic target for diverse diseases

    David C. Rubinsztein;Patrice Codogno;Beth Levine

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

Frequent Co-Authors

Carol Brayne
Carol Brayne University of Cambridge
Fiona M. Menzies
Fiona M. Menzies University of Cambridge
Sovan Sarkar
Sovan Sarkar University of Birmingham
Julie Williams
Julie Williams Cardiff University
Simon Lovestone
Simon Lovestone University of Oxford
Michael John Owen
Michael John Owen Cardiff University
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Michael Gill
Michael Gill Trinity College Dublin
Cahir J. O'Kane
Cahir J. O'Kane University of Cambridge
Brian A. Lawlor
Brian A. Lawlor Trinity College Dublin

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